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Postural Tachycardia Syndrome
Open-data reference.
20 US clinical trials · 4 currently recruiting
Active & Recent Trials
Inappropriate Sinus Tachycardia Registry
AtriCure
NCT05107635
Autoimmune Basis for Postural Tachycardia Syndrome
University of Oklahoma
NCT05043051
A Study of Pyridostigmine in Postural Tachycardia Syndrome
Mayo Clinic
NCT00409435
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
Virginia Commonwealth University
NCT05618054
POTS NET mRNA Functional Correlation With NET Activity
Vanderbilt University Medical Center
NCT03218761
Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening
Vanderbilt University
NCT01783288
Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)
Satish R. Raj
NCT00692471
Autonomic Determinants of POTS - Pilot 2
Vanderbilt University Medical Center
NCT04140721
Autonomic Determinants of POTS - Pilot1
Vanderbilt University Medical Center
NCT04050410
Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)
Vanderbilt University Medical Center
NCT01000350
Acute Salt Handling in Orthostatic Intolerance
Vanderbilt University
NCT00581633
Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
Alfredo Gamboa
NCT00962728
Phenotyping Mitochondrial and Immune Dysfunction in POTS With Targeted Clinical Intervention.
University of California, San Diego
NCT05409651
fMRI in Postural Tachycardia Syndrome
Milton S. Hershey Medical Center
NCT04137757
Modafinil and Cognitive Function in POTS
Vanderbilt University Medical Center
NCT01988883
Vagal Stimulation in POTS
Vanderbilt University Medical Center
NCT03124355
Qualitative Sweat Distribution During Tilt Table Procedure
Nationwide Children's Hospital
NCT02329548
Cognitive Dysfunction in Postural Tachycardia Syndrome
Vanderbilt University
NCT01366963
Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)
Mayo Clinic
NCT06268288
Assessment of Vascular Endothelial Function in Postural Tachycardia Syndrome
Vanderbilt University Medical Center
NCT01308099
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 4 |
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Postural Tachycardia Syndrome Trial Landscape
ClinicalTrials.gov lists 20 US studies indexed under Postural Tachycardia Syndrome, and 4 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Postural Tachycardia Syndrome shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Postural Tachycardia Syndrome is led by Vanderbilt University Medical Center with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Postural Tachycardia Syndrome?
PlainTrial tracks 20 US clinical trials for Postural Tachycardia Syndrome, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Postural Tachycardia Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.