Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Postural Tachycardia Syndrome: early-phase trial registry
4 of 20 indexed Postural Tachycardia Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #848 of 28,707 conditions by registered trial count.
20 US clinical trials · 4 currently recruiting · #848 of 28,707 conditions by registered trial count
Postural Tachycardia Syndrome: 20 US clinical trials tracked, 4 recruiting.
Postural Tachycardia Syndrome is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University Medical Center, running 7 of these trials.
Enrollment posture brief
Registry condition postural-tachycardia-syndrome
OPEN 4 | RECR 20% | LATE 0 | EARLY 5 | RANK #848 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (20% recruiting · 10 trials)
Postural Tachycardia Syndrome lists 4 open slots (20% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Postural Tachycardia Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Postural Tachycardia Syndrome is recruiting below its size-band peers.
4 of 20 indexed trials (20%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Postural Tachycardia Syndrome research.
Vanderbilt University Medical Center accounts for 7 of 20 trials (35%). 11 distinct sponsors appear on at least one study for this condition label.
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Most Postural Tachycardia Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 48 among the 20 trials that report a genuine target (sentinel values excluded). 16 of those (80%) plan for fewer than 100 participants.
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Postural Tachycardia Syndrome research is mostly interventional.
15 interventional and 5 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
20 total, page 1 of 1
Inappropriate Sinus Tachycardia Registry
AtriCure
NCT05107635
Autoimmune Basis for Postural Tachycardia Syndrome
University of Oklahoma
NCT05043051
A Study of Pyridostigmine in Postural Tachycardia Syndrome
Mayo Clinic
NCT00409435
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
Virginia Commonwealth University
NCT05618054
POTS NET mRNA Functional Correlation With NET Activity
Vanderbilt University Medical Center
NCT03218761
Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening
Vanderbilt University
NCT01783288
Sleep Actigraphy in Postural Tachycardia Syndrome (POTS)
Satish R. Raj
NCT00692471
Autonomic Determinants of POTS - Pilot 2
Vanderbilt University Medical Center
NCT04140721
Autonomic Determinants of POTS - Pilot1
Vanderbilt University Medical Center
NCT04050410
Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)
Vanderbilt University Medical Center
NCT01000350
Acute Salt Handling in Orthostatic Intolerance
Vanderbilt University
NCT00581633
Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
Alfredo Gamboa
NCT00962728
Phenotyping Mitochondrial and Immune Dysfunction in POTS With Targeted Clinical Intervention.
University of California, San Diego
NCT05409651
fMRI in Postural Tachycardia Syndrome
Milton S. Hershey Medical Center
NCT04137757
Modafinil and Cognitive Function in POTS
Vanderbilt University Medical Center
NCT01988883
Vagal Stimulation in POTS
Vanderbilt University Medical Center
NCT03124355
Qualitative Sweat Distribution During Tilt Table Procedure
Nationwide Children's Hospital
NCT02329548
Cognitive Dysfunction in Postural Tachycardia Syndrome
Vanderbilt University
NCT01366963
Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)
Mayo Clinic
NCT06268288
Assessment of Vascular Endothelial Function in Postural Tachycardia Syndrome
Vanderbilt University Medical Center
NCT01308099
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Postural Tachycardia Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Postural Tachycardia Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Postural Tachycardia Syndrome page
20 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Postural Tachycardia Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University Medical Center sponsors the most Postural Tachycardia Syndrome trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Postural Tachycardia Syndrome condition card totals 20 registered trials; most-linked intervention Placebo; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.