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NCT06539741 · ClinicalTrials.gov registry record
Variability in Analgesic Response to Ibuprofen
A clinical trial of Pain, Acute and Impacted Third Molar Tooth, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 200
- Enrollment target
- 1
- Study location
NCT06539741: Recruiting study of Pain, Acute and Impacted Third Molar Tooth, sponsored by University of Pennsylvania.
NCT06539741 is a study of Pain, Acute and Impacted Third Molar Tooth that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 200 participants, above the 95-participant average among 31 other Pain, Acute trials with a reported enrollment target (111% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06539741, a study of Pain, Acute and Impacted Third Molar Tooth, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain. However, there is variability in analgesic response, and some patients require supplemental opioids for adequate pain relief. The goal of this study is to identify the factors that contribute to the need for opioid after third molar extraction to help limit unnecessary opioid prescriptions in patients who will have good pain relief with ibuprofen alone.
Primary Outcome
Use of oxycodone in addition to ibuprofen + acetaminophen
Conditions Studied
Study Locations (1)
Pennsylvania
- University of Pennsylvania School of Dental Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-01-03 |
| Est. Completion | 2027-09 |
What NCT06539741 shows while recruiting
NCT06539741 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 95-participant average among 31 other Pain, Acute trials with a reported enrollment target (111% higher).
The record links to 2 conditions, with Pain, Acute appearing as the primary indexed condition, and to 0 interventions.
NCT06539741 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06539741 about?
NCT06539741 is a clinical study titled "Variability in Analgesic Response to Ibuprofen". Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, are recommended as first-line treatment for post-surgical dental pain. However, there is variability in analgesic response, and some patients require supplemental opioids for adequate pain relief. The goal of this study is to identify th...
What is the current status of trial NCT06539741?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2025-01-03. Estimated completion is 2027-09.
What conditions does trial NCT06539741 study?
This clinical trial studies the following conditions: Pain, Acute, Impacted Third Molar Tooth.
Who is sponsoring clinical trial NCT06539741?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06539741 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06539741's enrollment target sits among peer trials
200 3rd of 31 higher than 27 of 31 other Pain, Acute trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Acute trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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