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NCT06496646 · ClinicalTrials.gov registry record · NA

Antidepressant Adherence for Depressed Adults in Primary Care

A NA study of Depression, sponsored by University of Pennsylvania.

Recruiting
Registry status
NA
Development phase
525
Enrollment target
1
Study location

NCT06496646: Recruiting NA study of Depression, sponsored by University of Pennsylvania.

NCT06496646 is a NA study of Depression that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 525 participants, below the 785-participant average among 679 other Depression trials with a reported enrollment target (33% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT06496646, a NA study of Depression, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
NA
Development phase
525 participants
Enrollment target
1
Study location

Study Summary

The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

Primary Outcome

A reduction of 50% in depression score from baseline as assessed by PHQ-9

Conditions Studied

Interventions

  • BEHAVIORAL Arm 2 Intervention
  • BEHAVIORAL Arm 1 intervention

Study Locations (1)

Pennsylvania

  • University of Pennsylvania Health System - Philadelphia

Trial Details

FieldValue
Enrollment Target 525 participants
Start Date 2025-03-19
Est. Completion 2029-03-31
Phase NA
University of Pennsylvania

1,423 total trials

What NCT06496646 shows while recruiting

NCT06496646 is an interventional study that assigns participants to a tested intervention. The registered 525 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 679 other Depression trials with a reported enrollment target (33% lower).

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Arm 2 Intervention is the first listed.

NCT06496646 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06496646 about?

NCT06496646 is a clinical study titled "Antidepressant Adherence for Depressed Adults in Primary Care". The goal of this study is to test ways to help people improve their health and manage their medication for depression. This study will measure both medication adherence and depression outcomes.

What is the current status of trial NCT06496646?

This trial is currently recruiting. It is a NA study. The enrollment target is 525 participants. The study started on 2025-03-19. Estimated completion is 2029-03-31.

What conditions does trial NCT06496646 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT06496646?

The interventions under investigation include: Arm 2 Intervention (BEHAVIORAL), Arm 1 intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT06496646?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06496646 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06496646's enrollment target sits among peer trials

525 74th of 679 higher than 606 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06496646, the US trial registry maintained by the National Library of Medicine. NCT06496646 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.