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NCT06815237 · ClinicalTrials.gov registry record · Phase 2
Effects Ketone Supplement and Alcohol on Brain Metabolism
A Phase 2 study of Alcohol Drinking and MRI, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06815237: Recruiting Phase 2 study of Alcohol Drinking and MRI, sponsored by University of Pennsylvania.
NCT06815237 is a Phase 2 study of Alcohol Drinking and MRI that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 20 participants, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06815237, a Phase 2 study of Alcohol Drinking and MRI, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholic beverage, (3) no intervention. These interventions will be randomly assigned (meaning everyone receives all 3 interventions, but in different orders).
Primary Outcome
Use MRI imaging to measure the amount of Nicotinamide adenine dinucleotide levels in the brain measured in mmol/L in participants after receiving ketone supplement intervention compared to no intervention.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Kenetik
- OTHER Alcohol beverage
Study Locations (1)
Pennsylvania
- Center for Studies of Addiction - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-05-13 |
| Est. Completion | 2029-02 |
| Phase | Phase 2 |
What NCT06815237 shows while recruiting
NCT06815237 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Alcohol Drinking appearing as the primary indexed condition, and to 2 interventions - of which Kenetik is the first listed.
NCT06815237 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06815237 about?
NCT06815237 is a clinical study titled "Effects Ketone Supplement and Alcohol on Brain Metabolism". The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visits after three single-dose interventions: (1) drink a ketone supplement drink, (2) drink an alcoholic...
What is the current status of trial NCT06815237?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2025-05-13. Estimated completion is 2029-02.
What conditions does trial NCT06815237 study?
This clinical trial studies the following conditions: Alcohol Drinking, MRI, Ketosis.
What interventions are being tested in trial NCT06815237?
The interventions under investigation include: Kenetik (DIETARY_SUPPLEMENT), Alcohol beverage (OTHER).
Who is sponsoring clinical trial NCT06815237?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06815237 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alcohol Drinking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06815237's enrollment target sits among peer trials
20 76th of 85 higher than 6 of 85 other Alcohol Drinking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Drinking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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