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NCT06545084 · ClinicalTrials.gov registry record
Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)
A clinical trial of Apical Periodontitis, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT06545084 is a study of Apical Periodontitis that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 50 participants, below the 66-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (24% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06545084, a study of Apical Periodontitis, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to evaluate peri-radicular healing after root-end surgery using Leukocyte and Platelet Rich Fibrin. The study population includes patients diagnosed with persistent periapical pathology and scheduled for Endodontic Microsurgery at the University of Pennsylvania School of Dental Medicine, Department of Endodontics. Patients undergoing routine endodontic microsurgery and who meet the inclusion criteria will be given the opportunity to opt in to receive L-PRF in the osteotomy site to promote bone formation. Healing will be assessed radiographically and clinically at six, twelve, eighteen, and twenty-four months.
Conditions Studied
Interventions
- PROCEDURE Leukocyte and Platelet Rich Fibrin
Study Locations (1)
Pennsylvania
- Penn Dental Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-08-01 |
| Est. Completion | 2026-06-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06545084
The ClinicalTrials.gov registry entry for NCT06545084 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 66-participant average among 4 other Apical Periodontitis trials with a reported enrollment target (24% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Apical Periodontitis appearing as the primary indexed condition, and to 1 intervention - of which Leukocyte and Platelet Rich Fibrin is the first listed.
NCT06545084 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06545084 about?
NCT06545084 is a clinical study titled "Evaluation of Periapical Healing Following Endodontic Microsurgery With Leukocyte and Platelet Rich Fibrin (L-PRF)". The purpose of the study is to evaluate peri-radicular healing after root-end surgery using Leukocyte and Platelet Rich Fibrin. The study population includes patients diagnosed with persistent periapical pathology and scheduled for Endodontic Microsurgery at the University of Pennsylvania School of ...
What is the current status of trial NCT06545084?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-08-01. Estimated completion is 2026-06-30.
What conditions does trial NCT06545084 study?
This clinical trial studies the following conditions: Apical Periodontitis.
What interventions are being tested in trial NCT06545084?
The interventions under investigation include: Leukocyte and Platelet Rich Fibrin (PROCEDURE).
Who is sponsoring clinical trial NCT06545084?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06545084 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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