Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06789770 · ClinicalTrials.gov registry record
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
A clinical trial of Sleep Apnea, Obstructive, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT06789770: Recruiting study of Sleep Apnea, Obstructive, sponsored by University of Pennsylvania.
NCT06789770 is a study of Sleep Apnea, Obstructive that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 50 participants, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06789770, a study of Sleep Apnea, Obstructive, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.
Primary Outcome
Participants will be classified as oral breathers if more than 50% of their total breaths during DISE occur through the oral route; otherwise, they will be classified as nasal breathers. The pattern of upper airway collapse will be characterized using the VOTE classification system, a standardized DISE scoring tool assessing the Velum (V), Oropharynx (O), Tongue Base (T), and Epiglottis (E). Each anatomical site is graded on a 0-2 scale, where 0 = no obstruction, 1 = partial obstruction, and 2 =
Conditions Studied
Study Locations (1)
Pennsylvania
- Hospital at the University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-11-20 |
| Est. Completion | 2026-12 |
What NCT06789770 shows while recruiting
NCT06789770 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Sleep Apnea, Obstructive appearing as the primary indexed condition, and to 0 interventions.
NCT06789770 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06789770 about?
NCT06789770 is a clinical study titled "Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep". This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.
What is the current status of trial NCT06789770?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2024-11-20. Estimated completion is 2026-12.
What conditions does trial NCT06789770 study?
This clinical trial studies the following conditions: Sleep Apnea, Obstructive.
Who is sponsoring clinical trial NCT06789770?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06789770 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep Apnea, Obstructive
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06789770's enrollment target sits among peer trials
50 27th of 45 higher than 19 of 45 other Sleep Apnea, Obstructive trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep Apnea, Obstructive trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Do Endotypes Predict Response and Sequelae in OSA Patients
RECRUITING · Phase 2
-
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
RECRUITING · NA
-
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
RECRUITING · Phase 1
-
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
RECRUITING · Phase 3
-
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
RECRUITING · Phase 2
-
Home Apnea Testing in CHildren Trial
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI