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NCT06842745 · ClinicalTrials.gov registry record · Phase 2

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

A Phase 2 study of Stroke and Aphasia, sponsored by University of Pennsylvania.

Recruiting
Registry status
Phase 2
Development phase
24
Enrollment target
1
Study location

NCT06842745 is a Phase 2 study of Stroke and Aphasia that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 24 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06842745, a Phase 2 study of Stroke and Aphasia, is actively recruiting participants, sponsored by University of Pennsylvania.

RECRUITING
Registry status
Phase 2
Development phase
24 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke. The main questions this study aims to answer are: 1. Can TMS combined with SLT improve conversational speech and comprehension? 2. Can we identify specific behavioral and biological characteristics that would benefit most from the TMS and SLT treatment? Researchers will compare real TMS to sham (fake) TMS to see whether TMS can treat post-stroke mild aphasia. Participants will: * Complete a screening and medical intake to determine eligibility * Undergo a MRI * Participate in 10 consecutive sessions (Monday-Friday) of TMS and SLT treatment * Complete follow-up assessments 2 and 4 months after treatment

Conditions Studied

Stroke Aphasia Aphasia, Acquired Aphasia Following Cerebral Infarction

Interventions

  • BEHAVIORAL Speech-Language Therapy (SLT)
  • DEVICE Transcranial Magnetic Stimulation (TMS)

Study Locations (1)

Pennsylvania

  • University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2025-02-11
Est. Completion 2026-08-31
Phase Phase 2

Sponsor

University of Pennsylvania

1,423 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06842745

The ClinicalTrials.gov registry entry for NCT06842745 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Speech-Language Therapy (SLT) is the first listed.

NCT06842745 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06842745 about?

NCT06842745 is a clinical study titled "Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia". The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke. The main questions this study aims to answer are: 1. Can TMS combined with SLT improve c...

What is the current status of trial NCT06842745?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2025-02-11. Estimated completion is 2026-08-31.

What conditions does trial NCT06842745 study?

This clinical trial studies the following conditions: Stroke, Aphasia, Aphasia, Acquired, Aphasia Following Cerebral Infarction.

What interventions are being tested in trial NCT06842745?

The interventions under investigation include: Speech-Language Therapy (SLT) (BEHAVIORAL), Transcranial Magnetic Stimulation (TMS) (DEVICE).

Who is sponsoring clinical trial NCT06842745?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06842745 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.