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NCT06529575 · ClinicalTrials.gov registry record
Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children
A clinical trial of Pediatric ALL and Cardiac Defect, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 650
- Enrollment target
- 3
- Study locations
NCT06529575: Recruiting study of Pediatric ALL and Cardiac Defect, sponsored by University of Pennsylvania.
NCT06529575 is a study of Pediatric ALL and Cardiac Defect that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 650 participants, below the 1,617-participant average among 21 other Pediatric ALL trials with a reported enrollment target (60% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06529575, a study of Pediatric ALL and Cardiac Defect, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 650 participants
- Enrollment target
- 3
- Study locations
Study Summary
This multisite study seeks to understand whether and how pulse oximeter accuracy varies across children with different skin colors in real world clinical settings. Many factors can affect how well pulse oximeters work; for example, movement and even fingernail polish. Some studies in adults show that skin color may also affect the pulse oximeter reading. In this study, we will explore pulse oximeter accuracy in children of all skin colors who are undergoing cardiac catheterizations. The study will address limitations of prior work by objectively measuring skin color across multiple dimensions of color and comparing the the pulse oximeter reading to the "gold standard" blood sample measurement.
Primary Outcome
Pulse oximeter bias is the difference between the pulse oximeter value (estimated % oxygen saturation measured via pulse oximeter) and the gold standard measure of arterial oxygen saturation (% oxygen saturation in blood sample measured via co-oximeter).
Conditions Studied
Study Locations (3)
New York
- Columbia University Medical Center - New York
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Texas
- Texas Children's Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 650 participants |
| Start Date | 2024-08-14 |
| Est. Completion | 2028-12 |
What NCT06529575 shows while recruiting
NCT06529575 is an observational study that tracks outcomes without assigning an intervention. The registered 650 participants enrollment target is mid-sized for trials with a published cap, below the 1,617-participant average among 21 other Pediatric ALL trials with a reported enrollment target (60% lower).
The record links to 2 conditions, with Pediatric ALL appearing as the primary indexed condition, and to 0 interventions.
NCT06529575 reports a single indexed study location in New York, Pennsylvania, Texas.
Frequently Asked Questions
What is clinical trial NCT06529575 about?
NCT06529575 is a clinical study titled "Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children". This multisite study seeks to understand whether and how pulse oximeter accuracy varies across children with different skin colors in real world clinical settings. Many factors can affect how well pulse oximeters work; for example, movement and even fingernail polish. Some studies in adults show tha...
What is the current status of trial NCT06529575?
This trial is currently recruiting. The enrollment target is 650 participants. The study started on 2024-08-14. Estimated completion is 2028-12.
What conditions does trial NCT06529575 study?
This clinical trial studies the following conditions: Pediatric ALL, Cardiac Defect.
Who is sponsoring clinical trial NCT06529575?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06529575 being conducted?
This trial has 3 study locations across New York, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06529575's enrollment target sits among peer trials
650 3rd of 21 higher than 19 of 21 other Pediatric ALL trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pediatric ALL trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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