University of Pennsylvania
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, University of Pennsylvania sits in the top decile of US sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count).
University of Pennsylvania: 1,423 sponsored US clinical trials, 199 recruiting.
University of Pennsylvania sponsors 1,423 registered US clinical trials on ClinicalTrials.gov, 199 of them currently recruiting, and 982 completed. 130 of these trials are in Phase 3-4 (later-stage) and 339 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.
Top-decile sponsor footprint
University of Pennsylvania ranks in the top decile of sponsors by registered trial count (#15 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Open and recent trials
1,423 total, page 1 of 29
CD45BE-HSPC + CART-45 Cells
NCT07451054
TCR1188-ABC Cells in KRAS-mutated Cancers
NCT07594067
A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)
NCT07071935
Reward Sensitivity Digital Intervention for Suicide Risk
NCT07661901
huCART19-IL18-eDHFR Cells in Relapsed/Refractory Follicular Lymphoma
NCT07343934
Effects of Ketogenic Diet on Alcohol Intoxication
NCT07602270
Patient Navigation to Improve Surgical Access in Primary Hyperparathyroidism
NCT06562881
Intervention to Improve Parent Communication About Sexuality
NCT07672067
A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
NCT07542756
Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
NCT07548099
In-Shoe Loadsol Force Analysis Study LC1 Fractures
NCT07608107
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
NCT07042347
Conversational AI Platform for Early Pregnancy Care City-wide Recruitment: A Feasibility Study
NCT07197892
Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study
NCT07334418
Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine
NCT06788249
Virtual Reality in End Stage Kidney Disease
NCT06356168
Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships
NCT07246057
Kidney Transplant Improvement Through New Exercise Training to Increase Capacity
NCT07446296
OCD LIFU Target Engagement
NCT07558148
Sense4Safety Intervention
NCT07220668
A Pilot Trial of "Just ASK™" to Increase Discussions About Breast Cancer Clinical Trials
NCT07040891
Light Therapy in End Stage Kidney Disease
NCT06310161
Supraglottic Airway for Resuscitation in Preemies
NCT07419438
Click & Pick Study
NCT07422922
A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized Patients
NCT06954129
Stress Management and Mindfulness Intervention for Patients With Sickle Cell Disease
NCT07316478
Hysteroscopy for the Diagnosis and Treatment of Pregnancy of Unknown Location
NCT07469605
External Drainage of Thoracic Duct Lymph to Reduce Inflammatory Cytokines in Septic Shock Patients
NCT04855786
Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT
NCT06969261
Novel Endoscopic Bite Block
NCT06958250
Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease
NCT07085039
B.Brilliant Revelation Comparision Study
NCT07067788
Menstrual Cycle TMS Plasticity Pilot
NCT07180654
Structured Handoff Using Intelligent Framework for Transitions Trial
NCT07251907
Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy
NCT06904911
Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders
NCT06848530
Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM
NCT07209241
Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer
NCT07199764
Neurofeedback to Treat Depression - 2
NCT07159061
Transformative Research in Diabetic Nephropathy 2.0
NCT07444203
Use of Transcutaneous Electrical Nerve Stimulation Device, Reletex Reliefband, With Current ERAS (Enhanced Recovery After Surgery) Protocol to Further Decrease Postoperative Nausea and Vomiting in the Bariatric Surgical Patient Within the First 24 Hours Postoperatively.
NCT07063979
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
NCT06995651
The GRoceries Aimed at Increasing Nutrition Study
NCT07167004
18f-ftha Imaging OF THE Intestinal AND Central Lymphatic System
NCT07645573
MOv19-BBz CAR T Cells in FRa+ Cancers
NCT07116057
MethaLoad Dose-Finding Study
NCT06877858
Autobiographical Memory in Opioid Use Disorder
NCT06643988
Genicular Nerve Block for Knee Pain in the ED
NCT07158736
An Open-Label Study of Effectiveness of Immunomodulatory Medications for Patients With Relapsing Polychondritis
NCT06941376
Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder
NCT06559995
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 182 |
| Phase 2 | 157 |
| Phase 3 | 43 |
| Phase 4 | 87 |
Therapeutic Areas
What is open in the University of Pennsylvania pipeline
199 recruiting of 1,423 indexed (14% open); 982 completed (69%).
Phase mix: 130 late (III/IV) vs 339 early (I/II) (early-phase heavy).
Top condition: Obesity (17 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.