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NCT06968663 · ClinicalTrials.gov registry record · Phase 2
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
A Phase 2 study of Stroke and Aphasia, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 63
- Enrollment target
- 1
- Study location
NCT06968663 is a Phase 2 study of Stroke and Aphasia that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 63 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06968663, a Phase 2 study of Stroke and Aphasia, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 63 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke. The main questions this study aims to answer are: 1. Can TMS combined with mCILT improve overall speech? 2. Can we identify specific behavioral and biological characteristics that would benefit most from the TMS and mCILT treatment? Researchers will compare real TMS to sham (fake) TMS to see whether TMS can treat subacute aphasia. Importantly, this trial will use electric field guided TMS to identify optimal and individualized stimulation intensity and site targeting. Participants will: * Complete a screening and medical intake to determine eligibility * Undergo MRI scans * Participate in 10 consecutive sessions (Monday-Friday) of TMS and mCILT treatment * Complete follow-up assessments immediately and 4 months after treatment
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation (TMS)
- BEHAVIORAL Modified Constraint Induced Language Therapy (mCILT)
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 63 participants |
| Start Date | 2024-08-01 |
| Est. Completion | 2029-07-31 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06968663
The ClinicalTrials.gov registry entry for NCT06968663 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The listed sponsor is University of Pennsylvania, which has 1,423 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Transcranial Magnetic Stimulation (TMS) is the first listed.
NCT06968663 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06968663 about?
NCT06968663 is a clinical study titled "Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia". The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with modified Constraint Induced Language Therapy (mCILT) is an effective treatment for aphasia when delivered in the subacute stage after stroke. The main questions this study aims to answer are: 1...
What is the current status of trial NCT06968663?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 63 participants. The study started on 2024-08-01. Estimated completion is 2029-07-31.
What conditions does trial NCT06968663 study?
This clinical trial studies the following conditions: Stroke, Aphasia, Aphasia Following Cerebral Infarction.
What interventions are being tested in trial NCT06968663?
The interventions under investigation include: Transcranial Magnetic Stimulation (TMS) (DEVICE), Modified Constraint Induced Language Therapy (mCILT) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06968663?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06968663 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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