The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 5 of 14
Effects of Surgical Mask Use on Peak Torque, Total Work and Interset Fatigability During Isokinetic Strength Testing
NCT04706299
Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity
NCT04614545
Postoperative Consequences of Intraoperative NOL Titration
NCT04679818
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
NCT04748120
Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
NCT04561375
Dual-task Augmented Reality Treatment for Parkinson's Disease
NCT04634331
Synbiotic Dietary Supplement and Gut Microbiota
NCT04097106
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Ulcerative Colitis (UC)
NCT04543994
Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:
NCT04501861
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's Colitis
NCT04548583
Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management
NCT04567225
Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation
NCT05690555
EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial
NCT04531176
STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
NCT04491617
Cooling Vest May Reduce Heat Stress During Surgery
NCT04511208
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
NCT04603417
Patient Priority Care for Older Adults With Multiple Chronic Conditions
NCT04510948
Virtual Reality Distraction for Reduction
NCT04416555
Role of Blood Management in Perioperative Outcomes
NCT04475497
Parallel Mapping for Ventricular Tachycardia
NCT04477499
Prevention of Opioid-Induced Hypoxemia
NCT04453722
Rhythmic Auditory Stimulation & Gait Training
NCT04314076
Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.
NCT04415879
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation
NCT04399980
Canakinumab in Covid-19 Cardiac Injury (The Three C Study)
NCT04365153
Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema
NCT04411693
Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation
NCT04342728
Post-Operative Constipation Following Total Knee Arthroplasty
NCT04380090
Cleveland Clinic Families Get Fit (CCFit) : A Family-based Activity-Monitor Intervention in Pediatric Obesity
NCT04312919
STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD Support
NCT04264182
Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity
NCT04361955
Novel Paradigms of Deep Brain Stimulation for Movement Disorders
NCT04563143
Novel Quantitative MRI for Axial Spondyloarthritis
NCT03778515
The Impact of Combined Mindfulness-Based Interventions and Nutritional Counseling on Physician Burnout
NCT04336436
Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease
NCT04000360
Validation Study for the Alertgy Non-invasive Continuous Glucose Monitor (ANICGM)
NCT04166032
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
NCT04150796
Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation
NCT03938688
Pomalidomide for the Treatment of Bleeding in HHT
NCT03910244
Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients
NCT04116684
Tracking Device Guided Feedback to Enhance Patient Physician Interaction
NCT04004806
Feasibility Study for Intrathoracic Nerve Stimulation
NCT04066374
Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant
NCT04340505
Virtual Visits to Optimize Research Trial Offerings to HF Patients
NCT04064541
Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple Sclerosis
NCT04000373
Improving SCI Rehabilitation Interventions by Retraining the Brain
NCT03892746
Nitrous Oxide for the Treatment of Complex Regional Pain Syndrome
NCT03879538
Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
NCT03955952
Comparison of Lithotripsy Urolithiasis Machines
NCT04069338
A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch
NCT03986281
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.