The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 5 of 14
Effects of Surgical Mask Use on Peak Torque, Total Work and Interset Fatigability During Isokinetic Strength Testing
NCT04706299
Comparing a Virtual vs. Face to Face Weight Management Program Using Phentermine for Patients With Overweight or Obesity
NCT04614545
Postoperative Consequences of Intraoperative NOL Titration
NCT04679818
Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
NCT04748120
Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
NCT04561375
Dual-task Augmented Reality Treatment for Parkinson's Disease
NCT04634331
Synbiotic Dietary Supplement and Gut Microbiota
NCT04097106
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Ulcerative Colitis (UC)
NCT04543994
Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:
NCT04501861
Study of Mesenchymal Stem Cells for the Treatment of Medically Refractory Crohn's Colitis
NCT04548583
Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management
NCT04567225
Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation
NCT05690555
EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial
NCT04531176
STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
NCT04491617
Cooling Vest May Reduce Heat Stress During Surgery
NCT04511208
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients
NCT04603417
Patient Priority Care for Older Adults With Multiple Chronic Conditions
NCT04510948
Virtual Reality Distraction for Reduction
NCT04416555
Role of Blood Management in Perioperative Outcomes
NCT04475497
Parallel Mapping for Ventricular Tachycardia
NCT04477499
Prevention of Opioid-Induced Hypoxemia
NCT04453722
Rhythmic Auditory Stimulation & Gait Training
NCT04314076
Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.
NCT04415879
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation
NCT04399980
Canakinumab in Covid-19 Cardiac Injury (The Three C Study)
NCT04365153
Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema
NCT04411693
Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation
NCT04342728
Post-Operative Constipation Following Total Knee Arthroplasty
NCT04380090
Cleveland Clinic Families Get Fit (CCFit) : A Family-based Activity-Monitor Intervention in Pediatric Obesity
NCT04312919
STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD Support
NCT04264182
Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity
NCT04361955
Novel Paradigms of Deep Brain Stimulation for Movement Disorders
NCT04563143
Novel Quantitative MRI for Axial Spondyloarthritis
NCT03778515
The Impact of Combined Mindfulness-Based Interventions and Nutritional Counseling on Physician Burnout
NCT04336436
Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease
NCT04000360
Validation Study for the Alertgy Non-invasive Continuous Glucose Monitor (ANICGM)
NCT04166032
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
NCT04150796
Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation
NCT03938688
Pomalidomide for the Treatment of Bleeding in HHT
NCT03910244
Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients
NCT04116684
Tracking Device Guided Feedback to Enhance Patient Physician Interaction
NCT04004806
Feasibility Study for Intrathoracic Nerve Stimulation
NCT04066374
Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant
NCT04340505
Virtual Visits to Optimize Research Trial Offerings to HF Patients
NCT04064541
Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple Sclerosis
NCT04000373
Improving SCI Rehabilitation Interventions by Retraining the Brain
NCT03892746
Nitrous Oxide for the Treatment of Complex Regional Pain Syndrome
NCT03879538
Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
NCT03955952
Comparison of Lithotripsy Urolithiasis Machines
NCT04069338
A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch
NCT03986281
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.