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NCT04365153 · ClinicalTrials.gov registry record · Phase 2

Canakinumab in Covid-19 Cardiac Injury (The Three C Study)

A Phase 2 study, sponsored by The Cleveland Clinic.

Completed
Registry status
Phase 2
Development phase
45
Enrollment target

NCT04365153 is a Phase 2 study that has completed, run by The Cleveland Clinic. The registered enrollment target is 45 participants.

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The verdict

NCT04365153, a Phase 2 study, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
Phase 2
Development phase
45 participants
Enrollment target

Study Summary

TThe purpose of this prospective, Phase 2, single center, blinded, randomized controlled study is to demonstrate as a proof of concept that early treatment with canakinumab prevents progressive heart and respiratory failure in patients with COVID-19 infection. These results will lead to and inform a Phase III randomized placebo-controlled trial.

Interventions

  • DRUG Placebos
  • DRUG Canakinumab Injection 600mg
  • DRUG Canakinumab Injection 300mg

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2020-04-24
Est. Completion 2021-04-01
Phase Phase 2

Sponsor

The Cleveland Clinic

688 total trials

What the Registry Record Tells You About NCT04365153

The ClinicalTrials.gov registry entry for NCT04365153 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebos is the first listed.

NCT04365153 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04365153 about?

NCT04365153 is a clinical study titled "Canakinumab in Covid-19 Cardiac Injury (The Three C Study)". TThe purpose of this prospective, Phase 2, single center, blinded, randomized controlled study is to demonstrate as a proof of concept that early treatment with canakinumab prevents progressive heart and respiratory failure in patients with COVID-19 infection. These results will lead to and inform a...

What is the current status of trial NCT04365153?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2020-04-24. Estimated completion is 2021-04-01.

What interventions are being tested in trial NCT04365153?

The interventions under investigation include: Placebos (DRUG), Canakinumab Injection 600mg (DRUG), Canakinumab Injection 300mg (DRUG).

Who is sponsoring clinical trial NCT04365153?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.