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NCT04501861 · ClinicalTrials.gov registry record · Phase 3
Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:
A Phase 3 study of Cardiac Disease, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- Phase 3
- Development phase
- 153
- Enrollment target
- 1
- Study location
NCT04501861: Completed Phase 3 study of Cardiac Disease, sponsored by The Cleveland Clinic.
NCT04501861 is a Phase 3 study of Cardiac Disease that has completed, run by The Cleveland Clinic. The registered enrollment target is 153 participants, below the 816-participant average among 24 other Cardiac Disease trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04501861, a Phase 3 study of Cardiac Disease, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 153 participants
- Enrollment target
- 1
- Study location
Study Summary
The relative increase in the mPAP with the same unit increase in MAP adjusted for baseline, and RV function assessed by GLS, between VP and NE in patients with normal and increased pulmonary artery pressure, who require vasopressor support during cardiac surgery.
Primary Outcome
The intraoperative mean pulmonary artery pressure(mPAP) adjusted for systemic mean arterial pressure(MAP), using a time-weighted average mPAP-to-MAP ratio measured during 20 minute period after chest closure
Conditions Studied
Interventions
- DRUG Norepinephrine
- DRUG Vasopressin
Study Locations (1)
Ohio
- Cleveland Clinic - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 153 participants |
| Start Date | 2020-11-05 |
| Est. Completion | 2024-12-31 |
| Phase | Phase 3 |
What the finished NCT04501861 record still lists
NCT04501861 is an interventional study that assigns participants to a tested intervention. The registered 153 participants enrollment target is mid-sized for trials with a published cap, below the 816-participant average among 24 other Cardiac Disease trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Cardiac Disease appearing as the primary indexed condition, and to 2 interventions - of which Norepinephrine is the first listed.
NCT04501861 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04501861 about?
NCT04501861 is a clinical study titled "Hemodynamic Effect of Norepinephrine Versus Vasopressin on the Pulmonary Circulation in Cardiac Surgery Patients:". The relative increase in the mPAP with the same unit increase in MAP adjusted for baseline, and RV function assessed by GLS, between VP and NE in patients with normal and increased pulmonary artery pressure, who require vasopressor support during cardiac surgery.
What is the current status of trial NCT04501861?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 153 participants. The study started on 2020-11-05. Estimated completion is 2024-12-31.
What conditions does trial NCT04501861 study?
This clinical trial studies the following conditions: Cardiac Disease.
What interventions are being tested in trial NCT04501861?
The interventions under investigation include: Norepinephrine (DRUG), Vasopressin (DRUG).
Who is sponsoring clinical trial NCT04501861?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04501861 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04501861's enrollment target sits among peer trials
153 12th of 24 higher than 11 of 24 other Cardiac Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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