The Cleveland Clinic

688 total trials 99 currently recruiting 437 completed

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Trial Pipeline

688 total, page 6 of 14

COMPLETED

Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Feasibility of the IC-Flow Device

NCT03860493

COMPLETED

Screening for Systemic Amyloidosis Via the Ligamentum Flavum

NCT03923920

COMPLETED

Cardiac Amyloidosis Screening at Trigger Finger Release

NCT03886155

COMPLETED

Bariatric Surgery-Induced Shift in Gut Microbiome and NAFLD

NCT04263376

COMPLETED NA

Cost-effectiveness of Forced Aerobic Exercise for Stroke Rehabilitation

NCT03819764

COMPLETED NA

SAMPAP Trial -Impact of a Novel Sleep Apnea Management Group Intervention on Positive Airway Pressure Adherence

NCT03835702

COMPLETED Early Phase 1

A Novel Approach for Brain Stimulation in Severe Stroke

NCT03868410

COMPLETED NA

Long QT Syndrome and Sleep Apnea

NCT03678311

COMPLETED NA

Urinary Retention After Laparoscopic Inguinal Hernia Repair: Comparing the Use of the Intraoperative Urinary Catheter

NCT03835351

TERMINATED

Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy

NCT04350424

COMPLETED

Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery

NCT03884634

COMPLETED Phase 3

Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine

NCT03831854

COMPLETED NA

Patient Satisfaction With Initial Phone Call Versus Office Visit Following Minimally Invasive Hysterectomy, a Randomized Controlled Trial.

NCT03809468

TERMINATED

Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome

NCT03794024

COMPLETED NA

Accuracy of the Apple Watch Series 4 for Detection of Heart Rhythm: A Pilot Study

NCT03798613

COMPLETED

Multicenter Imaging in Lead Extraction Study

NCT03772704

COMPLETED NA

Enhancing Caregiver Empathy by Empowering Patients to Discuss Their Values

NCT05055141

COMPLETED NA

Bridging Resources Improve the Development of Guideline-based Exercise

NCT03678974

COMPLETED NA

Online Mindfulness Program for Stress Management

NCT03753360

COMPLETED Phase 4

Reduction of Postoperative Gastrointestinal Dysmotility Following Total Laparoscopic Hysterectomy.

NCT03800745

COMPLETED NA

Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder

NCT03668873

COMPLETED Early Phase 1

Pectoral Fascial Plane and Serratus Anterior Plane Blocks With Bupivacaine v. Liposomal Bupivacaine

NCT03731221

TERMINATED

The Effect of Bariatric Surgery on Spermatogenesis

NCT03725696

COMPLETED

Diagnostic Utility of a Novel Point-of-Care Test of Calprotectin for Revision Total Knee Arthroplasty

NCT03694925

COMPLETED NA

Same Day Discharge After Minimally-invasive Sacrocolpopexy

NCT03730103

COMPLETED NA

Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy

NCT03681223

COMPLETED NA

Ventilation Strategy During General Anesthesia for Orthopedic Surgery: A Quality Improvement Project

NCT03657368

COMPLETED

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

NCT03043209

TERMINATED Phase 4

Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy

NCT03801356

COMPLETED NA

Improving Frailty With a Rigorous Ambulation Intervention in Lung Transplant Patients

NCT03636412

COMPLETED NA

Virtual Visits in Heart Failure Care Transitions

NCT03675828

COMPLETED NA

Danger Signs in Heart Failure- Effects of Video Education

NCT03657459

COMPLETED NA

A Computerized CBTi for Insomnia in Epilepsy

NCT03632889

COMPLETED NA

Accuracy of Commercially Available Heart Rate Monitors in Athletes

NCT03612063

COMPLETED NA

McGrath Videolaryngoscopy and Direct Laryngoscopy in Morbidly Obese Patients

NCT03467048

COMPLETED

Study of the Ability of a New Technique to Effectively Diagnose Movement Disorders

NCT03661021

COMPLETED NA

Hypotension Prediction Index for Blood Pressure Management

NCT03610165

TERMINATED Phase 4

Comparison of Clenpiq vs Golytely Bowel Preparation

NCT03198221

COMPLETED NA

Euflexxa for the Treatment of Osteoarthritis

NCT03459365

COMPLETED Phase 4

Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair

NCT03541941

COMPLETED

Telemedicine in Total Knee Arthroplasty Using Wearable Technology

NCT03406455

COMPLETED

Mirror Box Therapy As a Treatment Option for Functional Movement Disorders

NCT03660098

COMPLETED NA

A Fib Clinic of the Future Using KardiaPro Platform for Chronic Care of Patients With AF After Ablation Procedure

NCT03557034

COMPLETED NA

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

NCT03110081

COMPLETED NA

Improvement of Patient Satisfaction and Clinical Outcomes Using JointCOACH

NCT03499028

COMPLETED NA

Improvement of Patient Satisfaction and Overall Outcomes Using HealthLoop

NCT03481595

TERMINATED NA

Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery

NCT03455751

TERMINATED

Correlation Between Peripheral Venous Pressure and Central Venous Pressure in the Cardiac Intensive Care Unit

NCT03526497

COMPLETED

Patient Status Engine (PSE): EARLY FEASIBILITY AND USABILITY STUDY

NCT03480204

TERMINATED

Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis

NCT03464851

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Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What the Pipeline for The Cleveland Clinic Shows

According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.

The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.