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NCT04361955 · ClinicalTrials.gov registry record · NA
Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity
A NA study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- NA
- Development phase
- 66
- Enrollment target
NCT04361955: Completed NA study, sponsored by The Cleveland Clinic.
NCT04361955 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 66 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04361955, a NA study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 66 participants
- Enrollment target
Study Summary
The purpose of this study is to learn about how deep brain stimulation (DBS) affects brain activity in those with Parkinson's disease (PD) and essential tremor (ET). The effect of therapeutic and non-therapeutic stimulation settings will be assessed. Additionally, DBS effects in the presence and absence of anti-PD medication will be studied. Also of interest are differences in stimulation effects while at rest versus while performing a task.
Primary Outcome
1\) Characterize the spatial and temporal characteristics of cortical activity evoked in response to deep brain stimulation of the targeted subcortical nucleus. 2) Determine the effect of dopamine replacement therapy (DRT) on the spatial and temporal characteristics of the evoked cortical potentials (PD Patients only). 3) Determine the effect of patient state (rest vs. active) spatial and temporal characteristics of the evoked cortical potentials.
Interventions
- OTHER EEG
- OTHER EMG
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2020-01-31 |
| Est. Completion | 2023-08-10 |
| Phase | NA |
What the finished NCT04361955 record still lists
NCT04361955 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which EEG is the first listed.
NCT04361955 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04361955 about?
NCT04361955 is a clinical study titled "Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity". The purpose of this study is to learn about how deep brain stimulation (DBS) affects brain activity in those with Parkinson's disease (PD) and essential tremor (ET). The effect of therapeutic and non-therapeutic stimulation settings will be assessed. Additionally, DBS effects in the presence and abs...
What is the current status of trial NCT04361955?
This trial is currently completed. It is a NA study. The enrollment target is 66 participants. The study started on 2020-01-31. Estimated completion is 2023-08-10.
What interventions are being tested in trial NCT04361955?
The interventions under investigation include: EEG (OTHER), EMG (OTHER).
Who is sponsoring clinical trial NCT04361955?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04361955's enrollment target sits among peer trials
66 1139th of 2000 higher than 857 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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