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NCT03892746 · ClinicalTrials.gov registry record · Phase 1
Improving SCI Rehabilitation Interventions by Retraining the Brain
A Phase 1 study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 47
- Enrollment target
NCT03892746: Completed Phase 1 study, sponsored by The Cleveland Clinic.
NCT03892746 is a Phase 1 study that has completed, run by The Cleveland Clinic. The registered enrollment target is 47 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03892746, a Phase 1 study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 47 participants
- Enrollment target
Study Summary
The Long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for cervical Spinal Cord Injury survivors. This Study will utilize a novel method of non-invasive brain stimulation in conjunction with upper limb training given for 15 sessions over several weeks up to 8 weeks. The Study will include the following site visits: * Eligibility Screening and Informed Consent Visit. * Four testing visit in which motor function of the upper limb and neurophysiology will be measured * Fifteen intervention visits during which patients will receive upper limb training in conjunction with non-invasive brain stimulation * Repeat testing of motor function and neurophysiology of the upper limb following completion of intervention visits * a Follow-up visit completed 3 months after the completion of interventions
Primary Outcome
UEMS is used in Spinal Cord injury to identify strength (muscle power) in patients with spinal cord injury. It involves a manual muscle test of five key muscles in each arm graded from 0 (no contraction) to 5 (normal strength). Each Arm can have a max score of 25 and the total score for the test is 50 points. The higher the value the more muscle strength the participant has and a higher change score means more improvement. The sum of scores for both arms is reported here.
Interventions
- DEVICE Active tDCS + task oriented practice
- DEVICE Sham tDCS + task oriented practice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 47 participants |
| Start Date | 2019-07-12 |
| Est. Completion | 2024-10-09 |
| Phase | Phase 1 |
What the finished NCT03892746 record still lists
NCT03892746 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower).
The record links to 0 conditions, and to 2 interventions - of which Active tDCS + task oriented practice is the first listed.
NCT03892746 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03892746 about?
NCT03892746 is a clinical study titled "Improving SCI Rehabilitation Interventions by Retraining the Brain". The Long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for cervical Spinal Cord Injury survivors. This Study will utilize a novel method of non-invasive brain stimulation in conjunction with upper limb training given for 15 sessions over severa...
What is the current status of trial NCT03892746?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2019-07-12. Estimated completion is 2024-10-09.
What interventions are being tested in trial NCT03892746?
The interventions under investigation include: Active tDCS + task oriented practice (DEVICE), Sham tDCS + task oriented practice (DEVICE).
Who is sponsoring clinical trial NCT03892746?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03892746's enrollment target sits among peer trials
47 1053rd of 2000 higher than 943 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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