Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04340505 · ClinicalTrials.gov registry record
Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant
A clinical trial, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- 30
- Enrollment target
NCT04340505: Completed study, sponsored by The Cleveland Clinic.
NCT04340505 is a clinical trial that has completed, run by The Cleveland Clinic. The registered enrollment target is 30 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04340505 has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
Study Summary
We will prospectively observe patients with uveitis who are either active or were recently active in the previous 6 months and are treated with the i-FA implant. All of the patients will have standard clinical exams at baseline and image quantification of their inflammation using OCT, OCTA and UWFFA (if needed). At baseline, ETDRS vision will be measured. Patients will be followed for 12 months months. During follow-up repeat imaging will be performed along with standard examinations, visual acuity and contrast sensitivity measurements. At the final visit, all tests will be repeated. Data collected will be analyzed using statistical software package. Correlations between changes in imaging quantification of inflammation scores and changes in visual acuity, clinical grades of inflammation, and contract sensitivity will be calculated.
Primary Outcome
Automated imaging markers of inflammation will be analyzed using customized software to assess impact of fluocinolone acetonide implant on imaging.
Interventions
- DRUG Fluocinolone Acetonide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2019-08-08 |
| Est. Completion | 2026-02-01 |
What the finished NCT04340505 record still lists
NCT04340505 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Fluocinolone Acetonide is the first listed.
NCT04340505 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04340505 about?
NCT04340505 is a clinical study titled "Imaging of Uveitis Patients Receiving Injectable Fluocinolone Acetonide Implant". We will prospectively observe patients with uveitis who are either active or were recently active in the previous 6 months and are treated with the i-FA implant. All of the patients will have standard clinical exams at baseline and image quantification of their inflammation using OCT, OCTA and UWFFA...
What is the current status of trial NCT04340505?
This trial is currently completed. The enrollment target is 30 participants. The study started on 2019-08-08. Estimated completion is 2026-02-01.
What interventions are being tested in trial NCT04340505?
The interventions under investigation include: Fluocinolone Acetonide (DRUG).
Who is sponsoring clinical trial NCT04340505?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI