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NCT00187096 · ClinicalTrials.gov registry record · NA

Natural Killer (NK) Cell Transplantation for AML

A NA study, sponsored by St. Jude Children's Research Hospital.

Completed
Registry status
NA
Development phase
49
Enrollment target

NCT00187096: Completed NA study, sponsored by St. Jude Children's Research Hospital.

NCT00187096 is a NA study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 49 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00187096, a NA study, has completed, sponsored by St. Jude Children's Research Hospital.

COMPLETED
Registry status
NA
Development phase
49 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and efficacy of infusing natural killer cells from a donor as treatment for patients with acute myeloid leukemia in remission or who have experienced relapse.

Primary Outcome

Document the number of patients experiencing grade 3 or 4 toxicities during conditioning and up to 100 days post-transplant. Toxicities were identified using Common Toxicity Criteria V 3.0 criteria.

Interventions

  • DRUG Cyclophosphamide, Fludarabine, Clofarabine, Etoposide, Interleukin-2
  • PROCEDURE Natural Killer Cell Infusion
  • DEVICE CliniMACS System

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2005-09
Est. Completion 2013-03
Phase NA

What the finished NCT00187096 record still lists

NCT00187096 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 3 interventions - of which Cyclophosphamide, Fludarabine, Clofarabine, Etoposide, Interleukin-2 is the first listed.

NCT00187096 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00187096 about?

NCT00187096 is a clinical study titled "Natural Killer (NK) Cell Transplantation for AML". The purpose of this study is to assess the safety and efficacy of infusing natural killer cells from a donor as treatment for patients with acute myeloid leukemia in remission or who have experienced relapse.

What is the current status of trial NCT00187096?

This trial is currently completed. It is a NA study. The enrollment target is 49 participants. The study started on 2005-09. Estimated completion is 2013-03.

What interventions are being tested in trial NCT00187096?

The interventions under investigation include: Cyclophosphamide, Fludarabine, Clofarabine, Etoposide, Interleukin-2 (DRUG), Natural Killer Cell Infusion (PROCEDURE), CliniMACS System (DEVICE).

Who is sponsoring clinical trial NCT00187096?

This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00187096's enrollment target sits among peer trials

49 1379th of 2000 higher than 620 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00187096, the US trial registry maintained by the National Library of Medicine. NCT00187096 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.