St. Jude Children's Research Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, St. Jude Children's Research Hospital sits in the top decile of US sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count).

410 total trials 90 currently recruiting 227 completed early-phase tilt top decile by trial count

St. Jude Children's Research Hospital: 410 sponsored US clinical trials, 90 recruiting.

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Top-decile sponsor footprint

St. Jude Children's Research Hospital ranks in the top decile of sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 59/100

227 of 259 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

410 total, page 6 of 9

COMPLETED Phase 3

Melatonin Intervention For Neurocognitive Deficits in the St. Jude Lifetime Cohort

NCT01700959

COMPLETED NA

A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer

NCT01778127

COMPLETED

Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents

NCT01737554

COMPLETED Phase 1

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

NCT01644773

COMPLETED

St. Jude Cancer Education for Children Program: The Feasibility of Teacher Delivery (Pilot Study)

NCT01591213

COMPLETED

Cognitive, Academic and Psychosocial Functioning in Long-Term Survivors of Pediatric Stem Cell Transplantation

NCT01701492

COMPLETED

Body Image in Youth With HIV

NCT01673750

COMPLETED

Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting

NCT01673243

COMPLETED NA

Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy

NCT01674101

COMPLETED Phase 1

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

NCT01625351

TERMINATED Phase 2

T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

NCT01621477

COMPLETED NA

Massive Iron Deposit Assessment

NCT01572922

COMPLETED Phase 2

NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma

NCT01451515

COMPLETED

The Feasibility of Text Messaging to Assess Secondhand Smoke Exposure Among Youngsters With Cancer or Sickle Cell Disease

NCT01591187

COMPLETED Phase 1

Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma

NCT01576692

COMPLETED

Immune Reconstitution in Oncology Patients Following Autologous Stem Cell Transplant

NCT01540175

COMPLETED

Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program

NCT01569971

COMPLETED

Characterization of the Patient Population With Galactosialidosis

NCT01416467

COMPLETED Phase 2

Therapeutic Interventions For Pain Induced By Vincristine Treatment For Childhood Acute Lymphoblastic Leukemia (ALL)

NCT01506453

COMPLETED

Adolescent Loss: The Impact of Loss on Adolescent Oncology Patients

NCT01473862

COMPLETED Phase 3

Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line-Associated Bloodstream Infection

NCT01472965

COMPLETED Phase 1

Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma

NCT01498783

COMPLETED

The Feasibility Of a Daily Diary Methodology With a Pediatric Cancer Population

NCT01477255

COMPLETED NA

Constraint-Induced Movement Therapy in a Pediatric Oncology Population

NCT01447810

TERMINATED Phase 2

A Phase II Study of Intensity Modulated Radiation Therapy (IMRT) in High Risk Abdominal Neuroblastoma

NCT01440283

COMPLETED

Concurrent School Attendance And Cancer Therapy: The Experiences of 6-12 Year Old Pediatric Oncology Patients

NCT01383473

COMPLETED Phase 1

PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma

NCT01393912

COMPLETED Phase 2

Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen

NCT01328496

COMPLETED

Evaluating Therapeutic Boundaries Among Bedside Nurses At A Pediatric Hematology/Oncology Research Hospital

NCT01355731

COMPLETED NA

Computerized Intervention for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors

NCT01217996

COMPLETED

Genes Influencing Iron Overload State

NCT01158794

COMPLETED Phase 3

Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies

NCT01188798

COMPLETED

Epidemiology Of Respiratory Virus Infections In Children

NCT01167361

COMPLETED Phase 2

Immunogenicity of Fluzone HD,A High Dose Influenza Vaccine, In Children With Cancer or HIV

NCT01205581

COMPLETED

State Of The Art Functional Imaging In Sickle Cell Disease

NCT01137721

COMPLETED

St. Jude Cancer Education for Children Program: Evaluation at 4th-Grade Level

NCT01185093

COMPLETED

Sperm Banking Among Adolescents Newly Diagnosed With Cancer: Development of a Profiling and Referral Tool

NCT01152268

COMPLETED

The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2

NCT01123863

COMPLETED

Human Papillomavirus (HPV) Vaccination Among Survivors of Childhood Cancer

NCT01117389

COMPLETED NA

Vibration Intervention For Bone Enhancement In Childhood Cancer Survivors

NCT01010230

COMPLETED Phase 1

A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell Transplantation

NCT01068301

COMPLETED

Assessment of Sleep Complaints in Brain Tumor Survivors

NCT01102998

COMPLETED

Investigating the Needs of Childhood Cancer Survivors: The Unreported Experience

NCT01073735

COMPLETED NA

Evaluation of Cardiovascular Health Outcomes Among Survivors

NCT01003574

COMPLETED

Human Immune Responses Toward HIV-1 Envelope Antigens

NCT01344941

COMPLETED NA

Resistance and Aerobic Exercise for Subclinical Anthracycline Cardiomyopathy

NCT01071473

COMPLETED

Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors

NCT01014195

COMPLETED NA

A Comparison of the Success Rate Of Cannulation Between The Accuvein Apparatus And Standard Technique

NCT01042613

COMPLETED NA

Physical Activity to Modify Sequelae and Quality of Life in Childhood Acute Lymphoblastic Leukemia

NCT00902213

COMPLETED Phase 1

Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia

NCT00995137

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What is open in the St. Jude Children's Research Hospital pipeline

90 recruiting of 410 indexed (22% open); 227 completed (55%).

Phase mix: 19 late (III/IV) vs 173 early (I/II) (early-phase heavy).

Top condition: Sickle Cell Disease (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

St. Jude Children's Research Hospital: open-pipeline peers nationwide

Peers matched on 410 registered trials and 22% open enrollment, not the therapeutic-area sidebar.

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 10%15%20%25%30% Total trials Recruiting share St. Jude Children's Research HospitalTakedaUniversity of Kansas Medical CenterRutgers, The State University of New JerseyCase Comprehensive Cancer CenterNorthwell HealthVanda PharmaceuticalsBoston University Charles River CampusRegeneron Pharmaceuticals
St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 410 trials (± recruiting share)

Sponsors near 22% open enrollment (± trial volume)

What to do with this St. Jude Children's Research Hospital page

410 registered trials is a research-attention snapshot, not an endorsement of St. Jude Children's Research Hospital or any single study.

  • 90 of St. Jude Children's Research Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sickle Cell Disease is the condition St. Jude Children's Research Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sickle Cell Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

St. Jude Children's Research Hospital pipeline card: 410 registered trials from official public datasets.Report a data error.