Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00669305 · ClinicalTrials.gov registry record
Bone Marrow for Hemoglobinopathy Research
A clinical trial, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- 26
- Enrollment target
NCT00669305: Completed study, sponsored by St. Jude Children's Research Hospital.
NCT00669305 is a clinical trial that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 26 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00669305 has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- 26 participants
- Enrollment target
Study Summary
Human participants affected with sickle cell disease or thalassemia will donate bone marrow for use in experimental laboratory models to study potential new treatments. This is an observational study using bone marrow from human participants. The investigators will use sickle cell and thalassemia mouse models to observe and evaluate the possibility of correcting these disorders through genetic alterations or drug treatment.
Primary Outcome
The specific hypothesis to be tested is that a gene therapy vector, gene editing strategy, or drug modality can be designed that achieves a therapeutic level of globin production in transduced cells in mouse models.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2008-05-15 |
| Est. Completion | 2019-08-29 |
What the finished NCT00669305 record still lists
NCT00669305 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 26 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00669305 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00669305 about?
NCT00669305 is a clinical study titled "Bone Marrow for Hemoglobinopathy Research". Human participants affected with sickle cell disease or thalassemia will donate bone marrow for use in experimental laboratory models to study potential new treatments. This is an observational study using bone marrow from human participants. The investigators will use sickle cell and thalassemia mo...
What is the current status of trial NCT00669305?
This trial is currently completed. The enrollment target is 26 participants. The study started on 2008-05-15. Estimated completion is 2019-08-29.
Who is sponsoring clinical trial NCT00669305?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02646475 · 26 participants · Phase 1
Metabolic Effects of Angiotensin-(1-7)
- NCT03603223 · 26 participants · Phase 2
Pembrolizumab in Treating Participants With Leukoplakia
- NCT04063592 · 26 participants · NA
AMI Construction in Lower Extremity Residual Limbs
- NCT04906460 · 26 participants · Phase 1
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI