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NCT00908167 · ClinicalTrials.gov registry record · Phase 1
Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies
A Phase 1 study, sponsored by St. Jude Children's Research Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 44
- Enrollment target
NCT00908167: Completed Phase 1 study, sponsored by St. Jude Children's Research Hospital.
NCT00908167 is a Phase 1 study that has completed, run by St. Jude Children's Research Hospital. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00908167, a Phase 1 study, has completed, sponsored by St. Jude Children's Research Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
This is a Phase I study that determines a tolerable combination of sorafenib, when given sequentially with cytarabine and clofarabine and determines the feasibility of administering this drug combination in patients with relapsed or refractory hematologic malignancies including acute myeloid leukemia (AML), acute promyelocytic leukemia (APL), acute lymphoblastic leukemia (ALL), infantile leukemia (both either AML and/or ALL). AML with prior myelodysplastic syndrome (MDS), myelodysplastic/myeloproliferative neoplasms, and biphenotypic leukemia.
Interventions
- DRUG Cytarabine
- DRUG Sorafenib
- DRUG Clofarabine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2009-09 |
| Est. Completion | 2015-06 |
| Phase | Phase 1 |
What the finished NCT00908167 record still lists
NCT00908167 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).
The record links to 0 conditions, and to 3 interventions - of which Cytarabine is the first listed.
NCT00908167 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00908167 about?
NCT00908167 is a clinical study titled "Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignancies". This is a Phase I study that determines a tolerable combination of sorafenib, when given sequentially with cytarabine and clofarabine and determines the feasibility of administering this drug combination in patients with relapsed or refractory hematologic malignancies including acute myeloid leukemi...
What is the current status of trial NCT00908167?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2009-09. Estimated completion is 2015-06.
What interventions are being tested in trial NCT00908167?
The interventions under investigation include: Cytarabine (DRUG), Sorafenib (DRUG), Clofarabine (DRUG).
Who is sponsoring clinical trial NCT00908167?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00908167's enrollment target sits among peer trials
44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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