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NCT00623753 · ClinicalTrials.gov registry record · Phase 1

Evaluate Tolerability of a Multi-envelope, Prime-boost HIV Vaccine in Healthy Adults

A Phase 1 study, sponsored by St. Jude Children's Research Hospital.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT00623753: Clinical Trial Phase 1 study, sponsored by St. Jude Children's Research Hospital.

NCT00623753 is a Phase 1 study that was terminated before completion, run by St. Jude Children's Research Hospital. The registered enrollment target is 3 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00623753, a Phase 1 study, was terminated before completion, sponsored by St. Jude Children's Research Hospital.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

Vaccines have been very successful in preventing viral infections such as hepatitis B and the measles. Viral vaccines work by causing a person's immune system to make cells that will work against the virus. Due to the success in treating other viral infections, scientists are trying to develop a vaccine for human immunodeficiency virus (HIV). HIV infection is the cause of acquired immune deficiency syndrome (AIDS). AIDS is one of the most serious viral infections we know. This is a research study to evaluate the safety of a possible vaccine against HIV. Researchers want to determine that a person's immune system can respond to the HIV before he or she is exposed to it. Therefore that person may be able to be protected from infection with HIV.

Interventions

  • BIOLOGICAL EnvDNA, PolyEnv1, EnvPro

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2007-05
Est. Completion 2008-01
Phase Phase 1

Why NCT00623753 stopped before completion

NCT00623753 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 1 intervention - of which EnvDNA, PolyEnv1, EnvPro is the first listed.

NCT00623753 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00623753 about?

NCT00623753 is a clinical study titled "Evaluate Tolerability of a Multi-envelope, Prime-boost HIV Vaccine in Healthy Adults". Vaccines have been very successful in preventing viral infections such as hepatitis B and the measles. Viral vaccines work by causing a person's immune system to make cells that will work against the virus. Due to the success in treating other viral infections, scientists are trying to develop a vac...

What is the current status of trial NCT00623753?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2007-05. Estimated completion is 2008-01.

What interventions are being tested in trial NCT00623753?

The interventions under investigation include: EnvDNA, PolyEnv1, EnvPro (BIOLOGICAL).

Who is sponsoring clinical trial NCT00623753?

This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00623753's enrollment target sits among peer trials

3 1999th of 2000 higher than 1 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00623753, the US trial registry maintained by the National Library of Medicine. NCT00623753 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.