Children's Hospital of Philadelphia

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).

431 total trials 78 currently recruiting 300 completed early-phase tilt top decile by trial count

Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Top-decile sponsor footprint

Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 65/100

300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

431 total, page 1 of 9

RECRUITING NA

Nutrition Intervention for Pancreatic Cancer

NCT07554560

RECRUITING Phase 1

Vancomycin and Acute Kidney Injury in Sepsis Treatment - Intervention

NCT07084129

RECRUITING Phase 2

CEUS Evaluation of Hydrocephalus in Neonates and Infants

NCT06693752

RECRUITING

SPACE for Youth With Chronic Pain

NCT07425691

RECRUITING NA

Urinary Titin Biomarker in DMD

NCT07332013

RECRUITING NA

Sleep Promotion and Pediatric Hypertension

NCT06642246

RECRUITING NA

Supraglottic Airway for Resuscitation Trial

NCT07150923

RECRUITING Early Phase 1

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

NCT05555550

RECRUITING Phase 2

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

NCT07123961

RECRUITING NA

Optimal Ventilation for Cardiac Arrest

NCT07114510

RECRUITING NA

Physical Activity in CKD

NCT06624358

RECRUITING NA

Examining the Efficacy of the PRAISE With Coaching Program

NCT07191782

RECRUITING NA

Motivation for Daily Living Skills

NCT07159308

RECRUITING NA

SMART Implementation-Effectiveness Trial 1

NCT07137923

RECRUITING NA

SMART Implementation-Effectiveness Trial 2

NCT07138027

RECRUITING NA

Re-Engaging AYA Survivors in Cancer-Related Healthcare

NCT07138040

RECRUITING NA

Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia

NCT06534359

RECRUITING NA

Fontan Fitness Trial

NCT06918795

RECRUITING NA

Vancomycin Reduction Practices (VRP) in the NICU

NCT06772675

RECRUITING Phase 1

CD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for Lupus

NCT06839976

RECRUITING Phase 1

ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

NCT06364774

RECRUITING Phase 1

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

NCT06839456

RECRUITING NA

Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project)

NCT07020572

RECRUITING

Neurometabolic Profile of Individuals With Primary Mitochondrial Disease

NCT06890520

RECRUITING NA

Massage Impact on Sleep in Pediatric Oncology

NCT06892158

RECRUITING Phase 1

Validation of Nanosensor Oxygen Measurement

NCT06819683

RECRUITING NA

The Collaborative Care PrTNER Study

NCT06585631

RECRUITING Phase 1

Calculating Wall Shear Stress in Infant Pulmonary Veins

NCT06440408

RECRUITING NA

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

NCT06582693

RECRUITING NA

Driver Education Research Study

NCT06413927

RECRUITING Early Phase 1

18F-Fluciclovine PET-MRI in High-grade Glioma

NCT05553041

RECRUITING Phase 2

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

NCT06458036

RECRUITING NA

iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

NCT05442671

RECRUITING

Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy

NCT06389994

RECRUITING NA

Facilitating Access to Specialty Treatment

NCT05741411

RECRUITING Phase 2

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

NCT05783323

RECRUITING

Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

NCT06475976

RECRUITING Phase 1

Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas

NCT06156410

RECRUITING

Neurophysiologic Biomarkers in Rett Syndrome

NCT05932589

RECRUITING NA

Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study

NCT06085326

RECRUITING NA

Optimizing a Mobile Health Platform for Sleep Promotion and Obesity Prevention in Children

NCT05703347

RECRUITING

STXBP1 and SYNGAP1 Related Disorders Natural History Study

NCT06555965

RECRUITING NA

Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis

NCT05975671

RECRUITING

Diet and Motility in IBS

NCT07283341

RECRUITING Phase 1

Lurbinectedin in FET-Fused Tumors

NCT05918640

RECRUITING NA

Virtual Patient Navigation During a Pandemic

NCT06208852

RECRUITING

Synovial Sarcoma Registry / Biospecimen Repository

NCT05910307

RECRUITING NA

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

NCT05838690

RECRUITING

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

NCT06693778

RECRUITING NA

Home Apnea Testing in CHildren Trial

NCT05382754

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What is open in the Children's Hospital of Philadelphia pipeline

78 recruiting of 431 indexed (18% open); 300 completed (70%).

Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).

Top condition: Pediatric Cancer (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Children's Hospital of Philadelphia: open-pipeline peers nationwide

Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600800 0%10%20%30% Total trials Recruiting share Children's Hospital of PhiladelphiaNovo Nordisk A/SUniversity of Illinois at ChicagoVanderbilt UniversityDartmouth-Hitchcock Medical CenterWeill Medical College of Cornell UniversityUniversity of California, BerkeleyGeorge Washington UniversityHospital for Special Surgery, New York
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 431 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Children's Hospital of Philadelphia page

431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.

  • 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets.Report a data error.