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NCT05442671 · ClinicalTrials.gov registry record · NA
iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH
A NA study of Pulmonary Hypertension, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT05442671: Recruiting NA study of Pulmonary Hypertension, sponsored by Children's Hospital of Philadelphia.
NCT05442671 is a NA study of Pulmonary Hypertension that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 25 participants, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05442671, a NA study of Pulmonary Hypertension, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previously demonstrated that children with PH have less skeletal muscle mass in association with worse exercise performance. Interventions to increase physical activity and skeletal muscle mass may improve exercise performance and quality of life in children with PH. This study will use wearable activity monitoring devices to promote physical activity in a 16-week pilot intervention in children and teenager with PH.
Primary Outcome
Change in MVPA (min/day) will be measured by smartwatch accelerometer from baseline over the course of the intervention
Conditions Studied
Interventions
- BEHAVIORAL Exercise intervention
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2024-04-03 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT05442671 shows while recruiting
NCT05442671 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Exercise intervention is the first listed.
NCT05442671 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05442671 about?
NCT05442671 is a clinical study titled "iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH". Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previousl...
What is the current status of trial NCT05442671?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2024-04-03. Estimated completion is 2026-12-31.
What conditions does trial NCT05442671 study?
This clinical trial studies the following conditions: Pulmonary Hypertension.
What interventions are being tested in trial NCT05442671?
The interventions under investigation include: Exercise intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT05442671?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05442671 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pulmonary Hypertension
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05442671's enrollment target sits among peer trials
25 51st of 72 higher than 20 of 72 other Pulmonary Hypertension trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pulmonary Hypertension trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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