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NCT05442671 · ClinicalTrials.gov registry record · NA

iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH

A NA study of Pulmonary Hypertension, sponsored by Children's Hospital of Philadelphia.

Recruiting
Registry status
NA
Development phase
25
Enrollment target
1
Study location

NCT05442671 is a NA study of Pulmonary Hypertension that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 25 participants, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05442671, a NA study of Pulmonary Hypertension, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.

RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target
1
Study location

Study Summary

Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previously demonstrated that children with PH have less skeletal muscle mass in association with worse exercise performance. Interventions to increase physical activity and skeletal muscle mass may improve exercise performance and quality of life in children with PH. This study will use wearable activity monitoring devices to promote physical activity in a 16-week pilot intervention in children and teenager with PH.

Conditions Studied

Interventions

  • BEHAVIORAL Exercise intervention

Study Locations (1)

Pennsylvania

  • Children's Hospital of Philadelphia - Philadelphia

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2024-04-03
Est. Completion 2026-12-31
Phase NA

Sponsor

Children's Hospital of Philadelphia

431 total trials

What the Registry Record Tells You About NCT05442671

The ClinicalTrials.gov registry entry for NCT05442671 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 613-participant average among 72 other Pulmonary Hypertension trials with a reported enrollment target (96% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pulmonary Hypertension appearing as the primary indexed condition, and to 1 intervention - of which Exercise intervention is the first listed.

NCT05442671 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT05442671 about?

NCT05442671 is a clinical study titled "iTONE Trial (exercIse Training in pulmONary hypertEnsion) Exercise Program for Pediatric PH". Children with pulmonary hypertension (PH) engage in less physical activity than their peers. This is a concern since adult data support exercise as a non-pharmacologic treatment for PH. Despite adult data, therapeutic exercise has not been widely adopted in pediatric PH. Investigators have previousl...

What is the current status of trial NCT05442671?

This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2024-04-03. Estimated completion is 2026-12-31.

What conditions does trial NCT05442671 study?

This clinical trial studies the following conditions: Pulmonary Hypertension.

What interventions are being tested in trial NCT05442671?

The interventions under investigation include: Exercise intervention (BEHAVIORAL).

Who is sponsoring clinical trial NCT05442671?

This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05442671 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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