Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 31 recruiting now official registry

Pediatric Cancer clinical trials

Every US clinical trial registered for Pediatric Cancer — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

52 US clinical trials · 31 currently recruiting

The research picture

Pediatric Cancer has 52 registered US clinical trials, 31 of them open to new participants right now — about 60% of the total.

31
recruiting participants now
60%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
5
top sponsor: Children's Hospital of Philadelphia

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 5,000 participants

LIFE Cancer Survivorship Database for Pediatric Cancer

Children's Hospital Los Angeles

NCT01518400

RECRUITING 5,000 participants

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

National Cancer Institute (NCI)

NCT00001186

RECRUITING 1,050 participants

Childhood Cancer Predisposition Study (CCPS)

Emory University

NCT04511806

RECRUITING 1,000 participants

Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

NCT04715178

RECRUITING 500 participants

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

UNC Lineberger Comprehensive Cancer Center

NCT05096923

RECRUITING NA 450 participants

Multisite Implementation of COMPRENDO

University of California, San Diego

NCT06055296

RECRUITING 400 participants

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

St. Jude Children's Research Hospital

NCT04371315

RECRUITING NA 350 participants

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

Nemours Children's Clinic

NCT05294302

RECRUITING NA 300 participants

Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer

Johns Hopkins All Children's Hospital

NCT06346782

RECRUITING 250 participants

Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)

Erin Rowell

NCT05309746

RECRUITING NA 205 participants

Development and Evaluation of a Screening Approach for Sexual Dysfunction in AYA Patients With and Surviving Childhood Cancer

University of Colorado, Denver

NCT05524610

RECRUITING 150 participants

Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure

Hari Narayan

NCT04262830

RECRUITING 150 participants

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

Ann & Robert H Lurie Children's Hospital of Chicago

NCT05120518

RECRUITING 150 participants

Response to Influenza Vaccination in Pediatric Oncology Patients

St. Jude Children's Research Hospital

NCT05384288

RECRUITING NA 70 participants

Massage Impact on Sleep in Pediatric Oncology

Children's Hospital of Philadelphia

NCT06892158

RECRUITING Phase 1 64 participants

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

St. Jude Children's Research Hospital

NCT05468359

RECRUITING Phase 2 64 participants

Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients

Wake Forest University Health Sciences

NCT04948619

RECRUITING Phase 1 63 participants

Lurbinectedin in FET-Fused Tumors

Children's Hospital of Philadelphia

NCT05918640

RECRUITING NA 60 participants

Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention

Connecticut Children's Medical Center

NCT06982066

RECRUITING NA 60 participants

LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients

Wake Forest University Health Sciences

NCT05058508

RECRUITING NA 50 participants

Feasibility/Acceptability of Attentional-Control Training in Survivors

Children's National Research Institute

NCT05528939

RECRUITING 40 participants

Biomarkers of Resiliency In Childhood Cancer Surgery

Mayo Clinic

NCT06674811

RECRUITING NA 40 participants

Cancer Care Companion

Washington University School of Medicine

NCT07278778

RECRUITING NA 40 participants

PediRISE Feasibility

Dana-Farber Cancer Institute

NCT06283251

RECRUITING 35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

H. Lee Moffitt Cancer Center and Research Institute

NCT06423950

RECRUITING 32 participants

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Children's Hospital of Philadelphia

NCT05024929

RECRUITING NA 30 participants

Medically Tailored Meals for Kids

UNC Lineberger Comprehensive Cancer Center

NCT06814795

RECRUITING NA 15 participants

Digital Art Therapy for Young Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06789666

RECRUITING Phase 2 13 participants

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Children's Hospital of Philadelphia

NCT06458036

RECRUITING Phase 2 13 participants

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

Children's Hospital of Philadelphia

NCT05783323

RECRUITING NA 10 participants

Shareholder-driven Co-design and Piloting of Spanish Educational Videos About High Yield Pediatric Oncology Topics

University of Colorado, Denver

NCT07288476

ACTIVE NOT RECRUITING 57,816 participants

Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group

Children's Oncology Group

NCT01117168

ACTIVE NOT RECRUITING 1,000 participants

Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK Study

Children's Oncology Group

NCT05071859

ACTIVE NOT RECRUITING 367 participants

Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images

St. Jude Children's Research Hospital

NCT04125095

ACTIVE NOT RECRUITING NA 83 participants

Feasibility Usability & Acceptability Study: Symptom Reporting by Children Adolescents & Young Adults w/Cancer

Stanford University

NCT06824441

ACTIVE NOT RECRUITING 60 participants

Barriers and Facilitators in Access to OT/PT in Pediatric Cancer Survivors

M.D. Anderson Cancer Center

NCT05305950

ACTIVE NOT RECRUITING Phase 1 50 participants

Durvalumab and Tremelimumab for Pediatric Malignancies

AstraZeneca

NCT03837899

ACTIVE NOT RECRUITING NA 44 participants

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

University of California, San Francis

NCT03739372

ACTIVE NOT RECRUITING 42 participants

Understanding the Late Effects of Surviving a Pediatric Brain Tumor

Memorial Sloan Kettering Cancer Center

NCT03208387

ACTIVE NOT RECRUITING NA 35 participants

ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer

Connecticut Children's Medical Center

NCT05792566

ACTIVE NOT RECRUITING Early Phase 1 26 participants

A Study of N9 Chemotherapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT04947501

ACTIVE NOT RECRUITING NA 18 participants

Implementation of Family Psychosocial Risk Assessment in Pediatric Cancer

Nemours Children's Clinic

NCT04446728

ACTIVE NOT RECRUITING NA 17 participants

Feasibility Neurocognitive Outcome After Transplant

Stanford University

NCT02300961

ACTIVE NOT RECRUITING Early Phase 1 16 participants

An English/Spanish Mobile Augmented Reality Pain Assessment App for Hispanic/Latino Pediatric Cancer Patients

ALTality

NCT06635434

COMPLETED NA 445 participants

Symptom Screening Linked to Care Pathways

The Hospital for Sick Children

NCT04614662

COMPLETED 157 participants

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

Westat

NCT05255445

COMPLETED NA 73 participants

Translating ECHOS2 Into an mHealth Platform

Washington University School of Medicine

NCT05923242

COMPLETED Phase 4 49 participants

A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT

Phoenix Children's Hospital

NCT03176849

COMPLETED NA 33 participants

Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer

University of California, Irvine

NCT06622252

COMPLETED NA 15 participants

Expressive Storytelling to Share Adolescents/Young Adults Cancer Stories

Vanderbilt University

NCT04855487

COMPLETED Phase 1 11 participants

Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation

University of Alabama at Birmingham

NCT06298357

COMPLETED 4 participants

Lived Experiences of Adolescents in the Treatment Process of Cancer and the Impact on Occupations

Hackensack Meridian Health

NCT00456209

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pediatric Cancer Trial Landscape

ClinicalTrials.gov lists 52 US studies indexed under Pediatric Cancer, and 31 of those are currently open to recruitment — roughly 60% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pediatric Cancer shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pediatric Cancer is led by Children's Hospital of Philadelphia with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 52 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pediatric Cancer?

PlainTrial tracks 52 US clinical trials for Pediatric Cancer, of which 31 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pediatric Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →