Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 31 recruiting now early-phase tilt

Pediatric Cancer: early-phase trial registry

31 of 52 indexed Pediatric Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #271 of 28,707 conditions by registered trial count.

52 US clinical trials · 31 currently recruiting · #271 of 28,707 conditions by registered trial count

Pediatric Cancer: 52 US clinical trials tracked, 31 recruiting.

Pediatric Cancer is the subject of 52 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Children's Hospital of Philadelphia, running 5 of these trials.

Enrollment posture brief

Registry condition pediatric-cancer

OPEN 31 | RECR 60% | LATE 1 | EARLY 9 | RANK #271 | SPON 5

Nearest open-share peer: Nutrition, Healthy (59% recruiting · 32 trials)

Pediatric Cancer (this)60%Hidradenitis Suppurativa54.7%Idiopathic Pulmonary Fibrosi42.3%Depressive Disorder, Major26.4%Congestive Heart Failure15.4%
Open-enrollment share among volume-matched conditions near Pediatric Cancer

Pediatric Cancer lists 31 open slots (60% of 52 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pediatric Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pediatric Cancer is recruiting above its size-band peers.

    31 of 52 indexed trials (59.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pediatric Cancer trials is spread across many organizations.

    Children's Hospital of Philadelphia accounts for 5 of 52 trials (9.6%). 35 distinct sponsors appear on at least one study for this condition label.

  3. Most Pediatric Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 52 trials that report a genuine target (sentinel values excluded). 33 of those (63.5%) plan for fewer than 100 participants.

  4. Pediatric Cancer splits between interventional and observational designs.

    32 interventional and 20 observational studies make up this index (61.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23Phase 41

Open and recent trials

52 total, page 1 of 2

RECRUITING 5,000 participants

LIFE Cancer Survivorship Database for Pediatric Cancer

Children's Hospital Los Angeles

NCT01518400

RECRUITING 5,000 participants

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

National Cancer Institute (NCI)

NCT00001186

RECRUITING 1,050 participants

Childhood Cancer Predisposition Study (CCPS)

Emory University

NCT04511806

RECRUITING 1,000 participants

Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

NCT04715178

RECRUITING 500 participants

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

UNC Lineberger Comprehensive Cancer Center

NCT05096923

RECRUITING NA 450 participants

Multisite Implementation of COMPRENDO

University of California, San Diego

NCT06055296

RECRUITING 400 participants

Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children

St. Jude Children's Research Hospital

NCT04371315

RECRUITING NA 350 participants

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

Nemours Children's Clinic

NCT05294302

RECRUITING NA 300 participants

Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer

Johns Hopkins All Children's Hospital

NCT06346782

RECRUITING 250 participants

Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)

Erin Rowell

NCT05309746

RECRUITING NA 205 participants

Development and Evaluation of a Screening Approach for Sexual Dysfunction in AYA Patients With and Surviving Childhood Cancer

University of Colorado, Denver

NCT05524610

RECRUITING 150 participants

Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure

Hari Narayan

NCT04262830

RECRUITING 150 participants

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

Ann & Robert H Lurie Children's Hospital of Chicago

NCT05120518

RECRUITING 150 participants

Response to Influenza Vaccination in Pediatric Oncology Patients

St. Jude Children's Research Hospital

NCT05384288

RECRUITING NA 70 participants

Massage Impact on Sleep in Pediatric Oncology

Children's Hospital of Philadelphia

NCT06892158

RECRUITING Phase 1 64 participants

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

St. Jude Children's Research Hospital

NCT05468359

RECRUITING Phase 2 64 participants

Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients

Wake Forest University Health Sciences

NCT04948619

RECRUITING Phase 1 63 participants

Lurbinectedin in FET-Fused Tumors

Children's Hospital of Philadelphia

NCT05918640

RECRUITING NA 60 participants

Improving Communication Between AYA Oncology Patients and Clinicians: A Patient-Centered Intervention

Connecticut Children's Medical Center

NCT06982066

RECRUITING NA 60 participants

LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients

Wake Forest University Health Sciences

NCT05058508

RECRUITING NA 50 participants

Feasibility/Acceptability of Attentional-Control Training in Survivors

Children's National Research Institute

NCT05528939

RECRUITING 40 participants

Biomarkers of Resiliency In Childhood Cancer Surgery

Mayo Clinic

NCT06674811

RECRUITING NA 40 participants

Cancer Care Companion

Washington University School of Medicine

NCT07278778

RECRUITING NA 40 participants

PediRISE Feasibility

Dana-Farber Cancer Institute

NCT06283251

RECRUITING 35 participants

Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)

H. Lee Moffitt Cancer Center and Research Institute

NCT06423950

RECRUITING 32 participants

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

Children's Hospital of Philadelphia

NCT05024929

RECRUITING NA 30 participants

Medically Tailored Meals for Kids

UNC Lineberger Comprehensive Cancer Center

NCT06814795

RECRUITING NA 15 participants

Digital Art Therapy for Young Cancer Survivors

UNC Lineberger Comprehensive Cancer Center

NCT06789666

RECRUITING Phase 2 13 participants

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

Children's Hospital of Philadelphia

NCT06458036

RECRUITING Phase 2 13 participants

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

Children's Hospital of Philadelphia

NCT05783323

RECRUITING NA 10 participants

Shareholder-driven Co-design and Piloting of Spanish Educational Videos About High Yield Pediatric Oncology Topics

University of Colorado, Denver

NCT07288476

ACTIVE NOT RECRUITING 57,816 participants

Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group

Children's Oncology Group

NCT01117168

ACTIVE NOT RECRUITING 1,000 participants

Genetic Overlap Between Anomalies and Cancer in Kids in the Children's Oncology Group: The COG GOBACK Study

Children's Oncology Group

NCT05071859

ACTIVE NOT RECRUITING 367 participants

Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric Images

St. Jude Children's Research Hospital

NCT04125095

ACTIVE NOT RECRUITING NA 83 participants

Feasibility Usability & Acceptability Study: Symptom Reporting by Children Adolescents & Young Adults w/Cancer

Stanford University

NCT06824441

ACTIVE NOT RECRUITING 60 participants

Barriers and Facilitators in Access to OT/PT in Pediatric Cancer Survivors

M.D. Anderson Cancer Center

NCT05305950

ACTIVE NOT RECRUITING Phase 1 50 participants

Durvalumab and Tremelimumab for Pediatric Malignancies

AstraZeneca

NCT03837899

ACTIVE NOT RECRUITING NA 44 participants

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

University of California, San Francisco

NCT03739372

ACTIVE NOT RECRUITING 42 participants

Understanding the Late Effects of Surviving a Pediatric Brain Tumor

Memorial Sloan Kettering Cancer Center

NCT03208387

ACTIVE NOT RECRUITING NA 35 participants

ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer

Connecticut Children's Medical Center

NCT05792566

ACTIVE NOT RECRUITING Early Phase 1 26 participants

A Study of N9 Chemotherapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

NCT04947501

ACTIVE NOT RECRUITING NA 18 participants

Implementation of Family Psychosocial Risk Assessment in Pediatric Cancer

Nemours Children's Clinic

NCT04446728

ACTIVE NOT RECRUITING NA 17 participants

Feasibility Neurocognitive Outcome After Transplant

Stanford University

NCT02300961

ACTIVE NOT RECRUITING Early Phase 1 16 participants

An English/Spanish Mobile Augmented Reality Pain Assessment App for Hispanic/Latino Pediatric Cancer Patients

ALTality

NCT06635434

COMPLETED NA 445 participants

Symptom Screening Linked to Care Pathways

The Hospital for Sick Children

NCT04614662

COMPLETED 157 participants

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

Westat

NCT05255445

COMPLETED NA 73 participants

Translating ECHOS2 Into an mHealth Platform

Washington University School of Medicine

NCT05923242

COMPLETED Phase 4 49 participants

A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT

Phoenix Children's Hospital

NCT03176849

COMPLETED NA 33 participants

Intervention Development and Evaluation to Reduce Disparities in Quality of Life for Latino Families Impacted by Cancer

University of California, Irvine

NCT06622252

COMPLETED NA 15 participants

Expressive Storytelling to Share Adolescents/Young Adults Cancer Stories

Vanderbilt University

NCT04855487

Page 1 of 2 Next →

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 4 1

Named interventions

Most-linked intervention names on Pediatric Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
2 trials
13-week session program Other
1 trials
Standard Vitamin D3 Supplementation Dietary supplement
1 trials
Red Blood Cell (RBC) Transfusion Biological
1 trials
SPARK Symptom Screening Linked to Feedback to Providers Behavioral
1 trials
Computerized Intervention Authoring Software (CIAS) Behavioral
1 trials
Nurse-patient dyadic storytelling intervention Behavioral
1 trials
Delayed Start - Virtual Reality Behavioral
1 trials

US sites by state

Facility locations filed on Pediatric Cancer trials. A trial with sites in several states counts in each.

California 16 trials
Texas 10 trials
Tennessee 10 trials
Pennsylvania 8 trials
New York 7 trials
Massachusetts 7 trials
North Carolina 6 trials
Missouri 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pediatric Cancer page

52 registered trials, 31 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pediatric Cancer condition card totals 52 registered trials; most-linked intervention Cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.