Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06772675 · ClinicalTrials.gov registry record · NA

Vancomycin Reduction Practices (VRP) in the NICU

A NA study of Antibiotic Stewardship and Neonatal Sepsis, Late-Onset, sponsored by Children's Hospital of Philadelphia.

Recruiting
Registry status
NA
Development phase
13
Enrollment target
13
Study locations

NCT06772675: Recruiting NA study of Antibiotic Stewardship and Neonatal Sepsis, Late-Onset, sponsored by Children's Hospital of Philadelphia.

NCT06772675 is a NA study of Antibiotic Stewardship and Neonatal Sepsis, Late-Onset that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 13 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06772675, a NA study of Antibiotic Stewardship and Neonatal Sepsis, Late-Onset, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.

RECRUITING
Registry status
NA
Development phase
13 participants
Enrollment target
13
Study locations

Study Summary

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.

Primary Outcome

Proportion of late onset sepsis (LOS) evaluations performed with high fidelity. High fidelity is defined when the evaluation follows all three core components of VRP use.

Interventions

  • BEHAVIORAL External Facilitation

Study Locations (13)

California

  • Kaiser Permanente Modesto Medical Center - Modesto
  • Kaiser Permanente East Bay - Oakland Medical Center - Oakland
  • Kaiser Permanente Roseville Medical Center - Roseville
  • Kaiser Permanente San Francisco Medical Center - San Francisco
  • Kaiser Permanente San Leandro Medical Center - San Leandro
  • Kaiser Permanente Santa Clara Medical Center - Santa Clara
  • Kaiser Permanente Walnut Creek Medical Center - Walnut Creek

Pennsylvania

  • Lancaster General Hospital - Lancaster
  • Hospital of the University of Pennsylvania - Philadelphia
  • Pennsylvania Hospital - Philadelphia
  • Chester County Hospital - West Chester

New Jersey

  • Medical Center of Princeton - Plainsboro
  • Virtua Voorhees - Voorhees Township

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2025-06-02
Est. Completion 2027-09
Phase NA
Children's Hospital of Philadelphia

431 total trials

What NCT06772675 shows while recruiting

NCT06772675 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Antibiotic Stewardship appearing as the primary indexed condition, and to 1 intervention - of which External Facilitation is the first listed.

NCT06772675 lists 13 locations in 3 states (California, Pennsylvania, New Jersey).

Frequently Asked Questions

What is clinical trial NCT06772675 about?

NCT06772675 is a clinical study titled "Vancomycin Reduction Practices (VRP) in the NICU". This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-lev...

What is the current status of trial NCT06772675?

This trial is currently recruiting. It is a NA study. The enrollment target is 13 participants. The study started on 2025-06-02. Estimated completion is 2027-09.

What conditions does trial NCT06772675 study?

This clinical trial studies the following conditions: Antibiotic Stewardship, Neonatal Sepsis, Late-Onset, Vancomycin.

What interventions are being tested in trial NCT06772675?

The interventions under investigation include: External Facilitation (BEHAVIORAL).

Who is sponsoring clinical trial NCT06772675?

This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06772675 being conducted?

This trial has 13 study locations across California, New Jersey, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Antibiotic Stewardship

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06772675's enrollment target sits among peer trials

13 1911th of 2000 higher than 88 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03125655 · 13 participants

    Regulation of Inflammatory Genes in Psoriasis

  • NCT03774446 · 13 participants · Phase 2

    Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

  • NCT03830151 · 13 participants · Phase 1

    Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

  • NCT04573231 · 13 participants · Phase 2

    Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06772675, the US trial registry maintained by the National Library of Medicine. NCT06772675 (small enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.