Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06475976 · ClinicalTrials.gov registry record
Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia
A clinical trial of Bronchopulmonary Dysplasia, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- 130
- Enrollment target
- 1
- Study location
NCT06475976 is a study of Bronchopulmonary Dysplasia that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 130 participants, below the 232-participant average among 29 other Bronchopulmonary Dysplasia trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06475976, a study of Bronchopulmonary Dysplasia, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- 130 participants
- Enrollment target
- 1
- Study location
Study Summary
Bronchopulmonary Dysplasia (BPD), or chronic lung disease of prematurity, is the most consequential complication of preterm birth and is strong predictor of childhood pulmonary and neurodevelopmental disability, particularly in infants diagnosed with grade 3 BPD (ventilator dependence at 36 weeks' postmenstrual age), the most severe disease form. This study aims to (1) generate the first empirically defined phenotype classification system for grade 3 BPD developed using a rich array of objective and quantitative cardiopulmonary diagnostic, clinical, and biological data; and (2) define the association between phenotype subgroups and neurodevelopmental and respiratory outcomes through 2 years' corrected age.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Chest computed tomography (CT) with angiography
- DIAGNOSTIC_TEST Bronchoscopy with bronchoalveolar lavage
- DIAGNOSTIC_TEST Echocardiography
- DIAGNOSTIC_TEST 24 hour esophageal pH ("potential of hydrogen") - multichannel intraluminal impedance (MII) monitoring (reflux testing)
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2023-12-05 |
| Est. Completion | 2029-07-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06475976
The ClinicalTrials.gov registry entry for NCT06475976 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 232-participant average among 29 other Bronchopulmonary Dysplasia trials with a reported enrollment target (44% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Bronchopulmonary Dysplasia appearing as the primary indexed condition, and to 4 interventions - of which Chest computed tomography (CT) with angiography is the first listed.
NCT06475976 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06475976 about?
NCT06475976 is a clinical study titled "Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia". Bronchopulmonary Dysplasia (BPD), or chronic lung disease of prematurity, is the most consequential complication of preterm birth and is strong predictor of childhood pulmonary and neurodevelopmental disability, particularly in infants diagnosed with grade 3 BPD (ventilator dependence at 36 weeks' p...
What is the current status of trial NCT06475976?
This trial is currently recruiting. The enrollment target is 130 participants. The study started on 2023-12-05. Estimated completion is 2029-07-31.
What conditions does trial NCT06475976 study?
This clinical trial studies the following conditions: Bronchopulmonary Dysplasia.
What interventions are being tested in trial NCT06475976?
The interventions under investigation include: Chest computed tomography (CT) with angiography (DIAGNOSTIC_TEST), Bronchoscopy with bronchoalveolar lavage (DIAGNOSTIC_TEST), Echocardiography (DIAGNOSTIC_TEST), 24 hour esophageal pH ("potential of hydrogen") - multichannel intraluminal impedance (MII) monitoring (reflux testing) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06475976?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06475976 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bronchopulmonary Dysplasia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
RECRUITING · NA
-
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
RECRUITING
-
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
RECRUITING · Phase 2
-
Forced Oscillometry in Infants With Bronchopulmonary Dysplasia
RECRUITING
-
Transpyloric Versus Gastric Feeding in Bronchopulmonary Dysplasia
RECRUITING · NA
-
Ventilator Pressure and Optimization of Compliance and Hemodynamics
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.