University of Illinois at Chicago
Trial Pipeline
Using Implementation Science to Adapt a Targeted Transportation Intervention for Patients With Diabetic Retinopathy (PRONTO-EYE)
NCT07296952
STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study
NCT07269080
Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell Disease
NCT07402811
CBTi for the Treatment of Insomnia in Type 1 Diabetes
NCT07091318
Home Based Functional Balance Intervention for Multiple Sclerosis
NCT07355387
Reducing Overdose and Substance Use-related Stigma by Training Non-substance-using Friends and Family Members of People Who Use Opioids to Be Harm Reduction Champions
NCT06823453
Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery
NCT07111182
Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery
NCT07220850
Impaired Interlimb Coordination During Locomotion in Individuals With Chronic Stroke: Contributors and Effect on Walking Function
NCT07006818
Ischemic Preconditioning in Osteoarthritis and Back Pain
NCT07003113
Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
NCT07014111
Aging and Task-specific Training to Reduce Falls
NCT07094659
Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease
NCT06919081
Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement
NCT05736666
Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System
NCT06997120
Enhancing Diabetes Care: Exposome &Amp; Sensors
NCT06989008
Circadian Mechanisms, Glucose, and CV Risks in T1D
NCT06624046
An Intervention to Reduce Sedentary Behavior for Adults With Chronic Kidney Disease
NCT06754280
Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis
NCT05427695
EEG Biomarkers for OUD: Diagnostic, Prognostic, and Predictive Applications
NCT07085351
Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)
NCT06802315
Embracing Morning BReakfast and Activity for Classroom Engagement
NCT06555627
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
NCT04827420
Functional Balance Intervention in Multiple Sclerosis
NCT06341023
Digital InteGrated Behavioral TreatmeNt for Comorbid ObesITy and DeprEssion Among Racial and Ethnic Adults Age 50 and Older
NCT06636058
Effect of Continuing Versus Holding Metformin During Hospitalizations.
NCT06296836
LUNG-05: Investigating Chemotherapy Effectiveness for Non-Small Cell Lung Cancer (NSCLC) Metastatic Patients
NCT06576635
BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
NCT06441890
Feasibility Testing a Meditation App for Professionals Working With Youth in the Legal System
NCT06555172
IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)
NCT06266416
iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure
NCT06205225
Testing a Real-time Electronic Antiretroviral Adherence Monitoring Intervention
NCT06550804
TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure
NCT06473532
Time-restricted Eating Among Pregnant Females With Severe Obesity
NCT06477120
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
NCT05736198
GU-01: Glycyrrhizin in Prostate Cancer
NCT06378346
UIC Multi-Ethnic DCM Registry
NCT07145138
Transcranial Direct Current Stimulation in Conjunction with Individualized Physical Therapy for Individuals with Chronic Knee Pain
NCT06132412
HCV Tappt Adherence Study
NCT06263829
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
NCT06261463
Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device
NCT06410261
Self-Adhering Magnetic Device to Treat Corneal Exposure
NCT06291818
Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss
NCT05929508
School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays
NCT06145659
Optimizing the Floreciendo Sexual and Reproductive Health Workshop for Latina Teens and Female Caregivers: A Pilot
NCT06223165
The REACTplusNMES Trial: A Double-blinded RCT
NCT06127602
Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis
NCT06264336
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
NCT06504914
Prostate Single Port & Laser Enucleation Comparison Trial
NCT06224218
Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)
NCT06169371
BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
NCT06085742
Executive Function and Parenting in Childhood
NCT06241300
Study of Mental Health and Relationships
NCT06534827
Pilot Testing of a Structural Racism Intervention for Immigrant Latinx Families
NCT05991739
MindWalk Intervention for Older South Asian Caregivers of People With Cognitive Disabilities (CD)
NCT06002919
Resilience in East Asian Immigrants for Advance Care Planning Discussions
NCT06035549
The Gut Microbiome and Serum Metabolites As a Biological Mechanism Underlying Pain in Kidney Transplantation
NCT06206486
Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells
NCT05705024
StuDy AimED at Increasing AlCohol AbsTinEnce
NCT05778734
Enhancing Immune Health Randomized Controlled Trial
NCT05639881
Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis
NCT05051618
Improving the Health and Social Participation of People With Disabilities From Underrepresented Groups Post COVID
NCT05792852
MADRE (Mammograms Available Due to Research and Education)
NCT05841355
Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
NCT04518657
Empowering Vulnerable and Resilient Latinas to Obtain Breast Cancer Care
NCT05483283
Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma
NCT05344833
A Pilot Phase II Study of Maintenance Cabozantinib Plus Pembrolizumab for Patients With Metastatic Squamous Non-Small Cell Lung Cancer (sqNSCLC)
NCT05613413
Home-based FES Training in People With Chronic Stroke
NCT05849532
Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
NCT05573308
Examining the Effects of a Remotely-delivered, Racially-tailored Exercise Training Program for Immediate and Sustained Improvements in Walking Dysfunction, Symptoms, and Health-related Quality of Life (HRQOL) Among African-Americans With Multiple Sclerosis (MS) Residing in Rural Environments.
NCT05516537
Better Lifestyle Counseling for African American Women During Pregnancy
NCT05234125
Implementation of Population Cancer Genetic Services in Federally Qualified Health Centers (FQHC)
NCT05664867
Time Restricted Eating During Chemotherapy for Breast Cancer
NCT05259410
BUILT Family Lifestyle Program for Children with ADHD
NCT05464056
Multivariable Artificial Pancreas: Detecting and Mitigating Unannounced Physical Activity and Acute Psychological Stress
NCT05145374
Healthy ReStart Intervention to Improve Health and Functioning
NCT05544344
Melanated Group Midwifery Care (MGMC)
NCT05365815
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
NCT05114798
Role of Adiposomes in Endothelial Dysfunction
NCT05199454
Perioperative Nutritional Optimization in Head and Neck Cancer Patients
NCT04449445
Utilization of a Videoscope in Periodontal Regeneration
NCT05275192
Patient Navigators for Children's Community Mental Health Services in High Poverty Urban Communities
NCT05294042
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
NCT04753359
BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
NCT04891068
Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD
NCT05192122
Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans
NCT05094297
Dual Task Perturbation Training for OAwMCI
NCT04938349
Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome
NCT04717427
Effect of NMES on Balance and Fall Risk in Chronic Stroke
NCT04957355
My ESSENCE - A Research Study on Mindfulness for African-Americans With Type 2 Diabetes
NCT05208164
Sleep, Diabetic Retinopathy and Melatonin
NCT04547439
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
NCT02347111
Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
NCT04477330
Analysis of Human ALS Tissues and Registry of ALS Patients
NCT05067179
Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)
NCT04427293
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron
NCT04150614
Convalescent Plasma as a Possible Treatment for COVID-19
NCT04442191
BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)
NCT04187105
DNA Methylation and Vascular Function
NCT03527420
Alternative Therapies for Improving Physical Function in Individuals With Stroke
NCT03869138
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 14 |
| Phase 2 | 19 |
| Phase 3 | 2 |
| Phase 4 | 8 |
Therapeutic Areas
What the Pipeline for University of Illinois at Chicago Shows
According to the ClinicalTrials.gov registry, University of Illinois at Chicago is linked to 421 US clinical trials across every stage of research activity. Of those, 331 studies are currently recruiting — about 79% of the sponsor's indexed portfolio — and 64 are already marked complete, representing roughly 15% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Illinois at Chicago reports 10 late-stage studies (Phase 3 and Phase 4 combined) and 33 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Illinois at Chicago is Multiple Sclerosis with 10 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.