Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05932589 · ClinicalTrials.gov registry record
Neurophysiologic Biomarkers in Rett Syndrome
A clinical trial of Rett Syndrome and Rett Syndrome, Atypical, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- 202
- Enrollment target
- 6
- Study locations
NCT05932589 is a study of Rett Syndrome and Rett Syndrome, Atypical that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 202 participants, below the 515-participant average among 18 other Rett Syndrome trials with a reported enrollment target (61% lower). The trial reports 6 study locations across 6 states.
The verdict
NCT05932589, a study of Rett Syndrome and Rett Syndrome, Atypical, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- 202 participants
- Enrollment target
- 6
- Study locations
Study Summary
The goal of this observational study is to identify candidate biomarkers in individuals with Rett Syndrome (RTT). The main questions it aims to answer are: * Do these biomarkers change during clinical changes in individuals with RTT? * Are biomarkers stable over time in clinically stable individuals? * Do these biomarkers correlate with severity of RTT? Participants will be asked to undergo an electroencephalogram (EEG) with measurements of Evoked Potentials (EP) to measure electrical activity in the brain. Researchers will compare findings in individuals with RTT to those in typically developing individuals to see if there are differences between the two groups.
Conditions Studied
Interventions
- OTHER EEG and Auditory and Visual Evoked Potentials (AEP and VEP)
- OTHER Clinical assessment
Study Locations (6)
California
- Children's Hospital of Los Angeles - Los Angeles
Colorado
- Children's Hospital Colorado - Aurora
Massachusetts
- Boston Children's Hospital - Brookline
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Tennessee
- Vanderbilt University Medical Center - Nashville
Texas
- Texas Children's Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 202 participants |
| Start Date | 2023-10-11 |
| Est. Completion | 2029-03-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05932589
The ClinicalTrials.gov registry entry for NCT05932589 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 202 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 515-participant average among 18 other Rett Syndrome trials with a reported enrollment target (61% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Rett Syndrome appearing as the primary indexed condition, and to 2 interventions - of which EEG and Auditory and Visual Evoked Potentials (AEP and VEP) is the first listed.
NCT05932589 reports 6 study locations spanning 6 distinct geographic areas - top geographies include California, Colorado, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05932589 about?
NCT05932589 is a clinical study titled "Neurophysiologic Biomarkers in Rett Syndrome". The goal of this observational study is to identify candidate biomarkers in individuals with Rett Syndrome (RTT). The main questions it aims to answer are: * Do these biomarkers change during clinical changes in individuals with RTT? * Are biomarkers stable over time in clinically stable individual...
What is the current status of trial NCT05932589?
This trial is currently recruiting. The enrollment target is 202 participants. The study started on 2023-10-11. Estimated completion is 2029-03-31.
What conditions does trial NCT05932589 study?
This clinical trial studies the following conditions: Rett Syndrome, Rett Syndrome, Atypical, RTT.
What interventions are being tested in trial NCT05932589?
The interventions under investigation include: EEG and Auditory and Visual Evoked Potentials (AEP and VEP) (OTHER), Clinical assessment (OTHER).
Who is sponsoring clinical trial NCT05932589?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05932589 being conducted?
This trial has 6 study locations across California, Colorado, Massachusetts, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rett Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Rett Syndrome Registry
RECRUITING
-
Cognitive Function in Rett Syndrome During Trofinetide Treatment
RECRUITING
-
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
RECRUITING
-
Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)
RECRUITING · NA
-
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
RECRUITING · NA
-
The Rett Syndrome Global Registry
RECRUITING
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.