Children's Hospital of Philadelphia

431 total trials 78 currently recruiting 300 completed

Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.

Trial Pipeline

431 total, page 2 of 9

RECRUITING Phase 1

Applying pGz in Mitochondrial Disease

NCT05569122

RECRUITING Phase 2

Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors

NCT05194397

RECRUITING Phase 1

Validation of Oxygen Nanosensor in Mitochondrial Myopathy

NCT04086329

RECRUITING

International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery

NCT05673499

RECRUITING NA

HOPS Study: A Conceptual Replication

NCT04465708

RECRUITING

BSGM to Evaluate Patients With GI Symptoms

NCT05880199

RECRUITING

Targeted Therapy to Increase RAI Uptake in Metastatic DTC

NCT05024929

RECRUITING Phase 1

Fibrosis and the Fontan

NCT04901975

RECRUITING NA

Sleep and Glycemic Control in Type 2 Diabetes Adolescents

NCT04213547

RECRUITING Phase 1

RH Genotype Matched RBC Transfusions

NCT04156893

RECRUITING

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study

NCT04338048

RECRUITING Early Phase 1

Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients

NCT04293042

RECRUITING NA

Positive Parenting Program in Foster Care

NCT03910491

RECRUITING NA

CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT

NCT03810196

RECRUITING Phase 2

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria

NCT03301038

RECRUITING Phase 4

CEUS for Blunt Abdominal Trauma in Children

NCT03490929

RECRUITING Early Phase 1

Pencil Beam Scanning in Patients With Renal Tumors

NCT03810651

RECRUITING Early Phase 1

Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH

NCT03107520

RECRUITING

Natural History Study of Mitochondrial Myopathy

NCT05250375

RECRUITING

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

NCT03419260

RECRUITING

The Myelin Disorders Biorepository Project

NCT03047369

RECRUITING

Quality of Pediatric Resuscitation in a Multicenter Collaborative

NCT02708134

RECRUITING

Evaluation of Outcome Metrics in Alexander Disease

NCT02714764

RECRUITING Early Phase 1

Fludarabine Based RIC for Bone Marrow Failure Syndromes

NCT02928991

RECRUITING Early Phase 1

Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC

NCT02356653

RECRUITING

Genetics of Insulin and Incretins in Cystic Fibrosis

NCT01852448

RECRUITING

ARPKD Database Study

NCT01401998

RECRUITING

Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs

NCT02493478

ACTIVE NOT RECRUITING Phase 2

24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs

NCT07543822

ACTIVE NOT RECRUITING Phase 2

24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs

NCT07549646

ACTIVE NOT RECRUITING

Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care

NCT07217002

ACTIVE NOT RECRUITING NA

Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain

NCT05834725

ACTIVE NOT RECRUITING NA

BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches

NCT06187662

ACTIVE NOT RECRUITING NA

Fiber Food Introduction in Pediatric Short Bowel Syndrome

NCT05432648

ACTIVE NOT RECRUITING

Gastric Ultrasound in Pediatric Trauma Patients

NCT05330351

ACTIVE NOT RECRUITING NA

Eliminating Monitor Overuse Trial (EMO Trial)

NCT05132322

ACTIVE NOT RECRUITING NA

Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis

NCT04891640

ACTIVE NOT RECRUITING NA

Discharge Stewardship in Children's Hospitals

NCT05826873

ACTIVE NOT RECRUITING NA

Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes

NCT04238949

ACTIVE NOT RECRUITING NA

Reducing Disparities in Behavioral Health Treatment for Children in Primary Care

NCT04082234

ACTIVE NOT RECRUITING Phase 4

Effectiveness of Contrast-Enhanced Ultrasound

NCT03473249

ACTIVE NOT RECRUITING

VIRTUUS Children's Study

NCT03719339

ACTIVE NOT RECRUITING NA

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

NCT03047746

ACTIVE NOT RECRUITING Phase 2

Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies

NCT02990819

ACTIVE NOT RECRUITING NA

Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia

NCT02549820

ACTIVE NOT RECRUITING Phase 2

Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies

NCT02323867

ACTIVE NOT RECRUITING Phase 2

Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders

NCT01050855

NOT YET RECRUITING NA

EoE Food Test Pilot Study

NCT07023380

TERMINATED

GentleFit Non-Invasive Ventilation (NIV) Interface Trial

NCT06833294

COMPLETED NA

Caregiver Implementation Strategies Field Pre-Test

NCT06770036

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What the Pipeline for Children's Hospital of Philadelphia Shows

According to the ClinicalTrials.gov registry, Children's Hospital of Philadelphia is linked to 431 US clinical trials across every stage of research activity. Of those, 78 studies are currently recruiting, about 18% of the sponsor's indexed portfolio, and 300 are already marked complete, representing roughly 70% of the total.

The phase mix for Children's Hospital of Philadelphia reports 35 late-stage studies (Phase 3 and Phase 4 combined) and 81 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Children's Hospital of Philadelphia is Pediatric Cancer with 5 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.