Children's Hospital of Philadelphia
Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.
Trial Pipeline
431 total, page 2 of 9
Applying pGz in Mitochondrial Disease
NCT05569122
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
NCT05194397
Validation of Oxygen Nanosensor in Mitochondrial Myopathy
NCT04086329
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
NCT05673499
HOPS Study: A Conceptual Replication
NCT04465708
BSGM to Evaluate Patients With GI Symptoms
NCT05880199
Targeted Therapy to Increase RAI Uptake in Metastatic DTC
NCT05024929
Fibrosis and the Fontan
NCT04901975
Sleep and Glycemic Control in Type 2 Diabetes Adolescents
NCT04213547
RH Genotype Matched RBC Transfusions
NCT04156893
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study
NCT04338048
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients
NCT04293042
Positive Parenting Program in Foster Care
NCT03910491
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT
NCT03810196
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
NCT03301038
CEUS for Blunt Abdominal Trauma in Children
NCT03490929
Pencil Beam Scanning in Patients With Renal Tumors
NCT03810651
Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
NCT03107520
Natural History Study of Mitochondrial Myopathy
NCT05250375
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
NCT03419260
The Myelin Disorders Biorepository Project
NCT03047369
Quality of Pediatric Resuscitation in a Multicenter Collaborative
NCT02708134
Evaluation of Outcome Metrics in Alexander Disease
NCT02714764
Fludarabine Based RIC for Bone Marrow Failure Syndromes
NCT02928991
Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
NCT02356653
Genetics of Insulin and Incretins in Cystic Fibrosis
NCT01852448
ARPKD Database Study
NCT01401998
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
NCT02493478
24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs
NCT07543822
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs
NCT07549646
Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care
NCT07217002
Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain
NCT05834725
BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches
NCT06187662
Fiber Food Introduction in Pediatric Short Bowel Syndrome
NCT05432648
Gastric Ultrasound in Pediatric Trauma Patients
NCT05330351
Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis
NCT04891640
Discharge Stewardship in Children's Hospitals
NCT05826873
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
NCT04238949
Reducing Disparities in Behavioral Health Treatment for Children in Primary Care
NCT04082234
Effectiveness of Contrast-Enhanced Ultrasound
NCT03473249
VIRTUUS Children's Study
NCT03719339
Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF
NCT03047746
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
NCT02990819
Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia
NCT02549820
Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies
NCT02323867
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
NCT01050855
EoE Food Test Pilot Study
NCT07023380
GentleFit Non-Invasive Ventilation (NIV) Interface Trial
NCT06833294
Caregiver Implementation Strategies Field Pre-Test
NCT06770036
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 42 |
| Phase 2 | 39 |
| Phase 3 | 18 |
| Phase 4 | 17 |
What the Pipeline for Children's Hospital of Philadelphia Shows
According to the ClinicalTrials.gov registry, Children's Hospital of Philadelphia is linked to 431 US clinical trials across every stage of research activity. Of those, 78 studies are currently recruiting, about 18% of the sponsor's indexed portfolio, and 300 are already marked complete, representing roughly 70% of the total.
The phase mix for Children's Hospital of Philadelphia reports 35 late-stage studies (Phase 3 and Phase 4 combined) and 81 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Children's Hospital of Philadelphia is Pediatric Cancer with 5 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.