Children's Hospital of Philadelphia
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Children's Hospital of Philadelphia sits in the top decile of US sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count).
Children's Hospital of Philadelphia: 431 sponsored US clinical trials, 78 recruiting.
Children's Hospital of Philadelphia sponsors 431 registered US clinical trials on ClinicalTrials.gov, 78 of them currently recruiting, and 300 completed. 35 of these trials are in Phase 3-4 (later-stage) and 81 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Pediatric Cancer, with 5 trials.
Top-decile sponsor footprint
Children's Hospital of Philadelphia ranks in the top decile of sponsors by registered trial count (#81 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
300 of 333 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (90.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
431 total, page 2 of 9
Applying pGz in Mitochondrial Disease
NCT05569122
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
NCT05194397
Validation of Oxygen Nanosensor in Mitochondrial Myopathy
NCT04086329
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
NCT05673499
HOPS Study: A Conceptual Replication
NCT04465708
BSGM to Evaluate Patients With GI Symptoms
NCT05880199
Targeted Therapy to Increase RAI Uptake in Metastatic DTC
NCT05024929
Fibrosis and the Fontan
NCT04901975
Sleep and Glycemic Control in Type 2 Diabetes Adolescents
NCT04213547
RH Genotype Matched RBC Transfusions
NCT04156893
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study
NCT04338048
Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients
NCT04293042
Positive Parenting Program in Foster Care
NCT03910491
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCT
NCT03810196
Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria
NCT03301038
CEUS for Blunt Abdominal Trauma in Children
NCT03490929
Pencil Beam Scanning in Patients With Renal Tumors
NCT03810651
Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
NCT03107520
Natural History Study of Mitochondrial Myopathy
NCT05250375
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
NCT03419260
The Myelin Disorders Biorepository Project
NCT03047369
Quality of Pediatric Resuscitation in a Multicenter Collaborative
NCT02708134
Evaluation of Outcome Metrics in Alexander Disease
NCT02714764
Fludarabine Based RIC for Bone Marrow Failure Syndromes
NCT02928991
Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
NCT02356653
Genetics of Insulin and Incretins in Cystic Fibrosis
NCT01852448
ARPKD Database Study
NCT01401998
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
NCT02493478
24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs
NCT07543822
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs
NCT07549646
Reducing Antibiotic Use by Implementation of Stewardship in Primary and Urgent Care
NCT07217002
Resilience Coaching for Adolescents With Chronic Musculoskeletal Pain
NCT05834725
BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches
NCT06187662
Fiber Food Introduction in Pediatric Short Bowel Syndrome
NCT05432648
Gastric Ultrasound in Pediatric Trauma Patients
NCT05330351
Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Biologic Abatement and Capturing Kids' Outcomes and Flare Frequency in Juvenile Spondyloarthritis
NCT04891640
Discharge Stewardship in Children's Hospitals
NCT05826873
Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes
NCT04238949
Reducing Disparities in Behavioral Health Treatment for Children in Primary Care
NCT04082234
Effectiveness of Contrast-Enhanced Ultrasound
NCT03473249
VIRTUUS Children's Study
NCT03719339
Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF
NCT03047746
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
NCT02990819
Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia
NCT02549820
Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies
NCT02323867
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
NCT01050855
EoE Food Test Pilot Study
NCT07023380
GentleFit Non-Invasive Ventilation (NIV) Interface Trial
NCT06833294
Caregiver Implementation Strategies Field Pre-Test
NCT06770036
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 42 |
| Phase 2 | 39 |
| Phase 3 | 18 |
| Phase 4 | 17 |
What is open in the Children's Hospital of Philadelphia pipeline
78 recruiting of 431 indexed (18% open); 300 completed (70%).
Phase mix: 35 late (III/IV) vs 81 early (I/II) (early-phase heavy).
Top condition: Pediatric Cancer (5 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Children's Hospital of Philadelphia: open-pipeline peers nationwide
Peers matched on 431 registered trials and 18% open enrollment, not the therapeutic-area sidebar.
Children's Hospital of Philadelphia sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 431 trials (± recruiting share)
- Novo Nordisk A/S · 431 trials · 8% recruiting
- University of Illinois at Chicago · 430 trials · 27% recruiting
- Vanderbilt University · 430 trials · 3% recruiting
- Dartmouth-Hitchcock Medical Center · 427 trials · 12% recruiting
Sponsors near 18% open enrollment (± trial volume)
- Weill Medical College of Cornell University · 18% recruiting · 701 trials
- University of California, Berkeley · 18% recruiting · 72 trials
- George Washington University · 18% recruiting · 133 trials
- Hospital for Special Surgery, New York · 18% recruiting · 194 trials
Related
What to do with this Children's Hospital of Philadelphia page
431 registered trials is a research-attention snapshot, not an endorsement of Children's Hospital of Philadelphia or any single study.
- 78 of Children's Hospital of Philadelphia's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Pediatric Cancer is the condition Children's Hospital of Philadelphia studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Pediatric Cancer trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Children's Hospital of Philadelphia pipeline card: 431 registered trials from official public datasets.Report a data error.