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NCT05975671 · ClinicalTrials.gov registry record · NA
Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis
A NA study of Sepsis and Septic Shock, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- NA
- Development phase
- 52,500
- Enrollment target
- 4
- Study locations
NCT05975671 is a NA study of Sepsis and Septic Shock that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 52,500 participants, above the 5,981-participant average among 90 other Sepsis trials with a reported enrollment target (778% higher). The trial reports 4 study locations across 4 states.
The verdict
NCT05975671, a NA study of Sepsis and Septic Shock, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- NA
- Development phase
- 52,500 participants
- Enrollment target
- 4
- Study locations
Study Summary
The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsis stakeholders and patients admitted to one of the participating PICUs during the study period. The intervention will at a minimum include: * Implementation of a clinical guideline indicating when vancomycin should and should not be used * Unit-level feedback on overall vancomycin use within and across centers * Clinician education.
Conditions Studied
Interventions
- BEHAVIORAL Multifaceted de-implementation strategy to reduce vancomycin overuse
Study Locations (4)
Georgia
- Children's Healthcare of Atlanta - Atlanta
Maryland
- Johns Hopkins Children's Center - Baltimore
Missouri
- St. Louis Children's Hospital - St Louis
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52,500 participants |
| Start Date | 2023-08-21 |
| Est. Completion | 2026-05 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05975671
The ClinicalTrials.gov registry entry for NCT05975671 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 52,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 5,981-participant average among 90 other Sepsis trials with a reported enrollment target (778% higher). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 7 conditions, with Sepsis appearing as the primary indexed condition, and to 1 intervention - of which Multifaceted de-implementation strategy to reduce vancomycin overuse is the first listed.
NCT05975671 reports 4 study locations spanning 4 distinct geographic areas - top geographies include Georgia, Maryland, Missouri.
Frequently Asked Questions
What is clinical trial NCT05975671 about?
NCT05975671 is a clinical study titled "Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis". The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsi...
What is the current status of trial NCT05975671?
This trial is currently recruiting. It is a NA study. The enrollment target is 52,500 participants. The study started on 2023-08-21. Estimated completion is 2026-05.
What conditions does trial NCT05975671 study?
This clinical trial studies the following conditions: Sepsis, Septic Shock, Sepsis, Severe, Sepsis Mrsa, Sepsis Bacteremia.
What interventions are being tested in trial NCT05975671?
The interventions under investigation include: Multifaceted de-implementation strategy to reduce vancomycin overuse (BEHAVIORAL).
Who is sponsoring clinical trial NCT05975671?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05975671 being conducted?
This trial has 4 study locations across Georgia, Maryland, Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.