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NCT07114510 · ClinicalTrials.gov registry record · NA

Optimal Ventilation for Cardiac Arrest

A NA study of Cardiac Arrest (CA), sponsored by Children's Hospital of Philadelphia.

Recruiting
Registry status
NA
Development phase
1,530
Enrollment target
20
Study locations

NCT07114510 is a NA study of Cardiac Arrest (CA) that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 1,530 participants, above the 56-participant average among 3 other Cardiac Arrest (CA) trials with a reported enrollment target (2632% higher). The trial reports 20 study locations across 16 states.

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The verdict

NCT07114510, a NA study of Cardiac Arrest (CA), is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.

RECRUITING
Registry status
NA
Development phase
1,530 participants
Enrollment target
20
Study locations

Study Summary

Pediatric cardiac arrest is a life-threatening problem affecting \>15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors. The objective of this study is to evaluate the effectiveness of the OPTI-VENT bundle to improve survival to discharge with favorable neurological outcome (Pediatric Cerebral Performance Category Score 1-2 or no change from baseline) among children receiving at least 1 minute of CPR.

Conditions Studied

Interventions

  • OTHER OPTI-VENT Bundle
  • OTHER Transition
  • OTHER None - control

Study Locations (20)

Texas

  • Dell Children's Medical Center - Austin
  • Medical City Children's Hospital - Dallas
  • UT Southwestern Medical Center - Dallas

California

  • CHOC - Orange
  • Lucile Packard Children's Hospital Stanford - Palo Alto

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati
  • Nationwide Children's Hospital - Columbus

Colorado

  • Children's Hospital Colorado - Denver

Delaware

  • Nemours Children's Health - Wilmington

Georgia

  • Children's Healthcare of Atlanta - Atlanta

Indiana

  • Riley Children's Health - Indianapolis

Iowa

  • Stead Family Children's Hospital - Iowa City

Trial Details

FieldValue
Enrollment Target 1,530 participants
Start Date 2025-10-01
Est. Completion 2030-03-31
Phase NA

Sponsor

Children's Hospital of Philadelphia

431 total trials

What the Registry Record Tells You About NCT07114510

The ClinicalTrials.gov registry entry for NCT07114510 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 1,530 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 56-participant average among 3 other Cardiac Arrest (CA) trials with a reported enrollment target (2632% higher). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cardiac Arrest (CA) appearing as the primary indexed condition, and to 3 interventions - of which OPTI-VENT Bundle is the first listed.

NCT07114510 reports 20 study locations spanning 16 distinct geographic areas - top geographies include Texas, California, Ohio.

Frequently Asked Questions

What is clinical trial NCT07114510 about?

NCT07114510 is a clinical study titled "Optimal Ventilation for Cardiac Arrest". Pediatric cardiac arrest is a life-threatening problem affecting \>15,000 hospitalized children each year. Less than half of these children survive to hospital discharge, and neurologic morbidity is common among survivors. The objective of this study is to evaluate the effectiveness of the OPTI-VENT...

What is the current status of trial NCT07114510?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,530 participants. The study started on 2025-10-01. Estimated completion is 2030-03-31.

What conditions does trial NCT07114510 study?

This clinical trial studies the following conditions: Cardiac Arrest (CA).

What interventions are being tested in trial NCT07114510?

The interventions under investigation include: OPTI-VENT Bundle (OTHER), Transition (OTHER), None - control (OTHER).

Who is sponsoring clinical trial NCT07114510?

This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07114510 being conducted?

This trial has 20 study locations across California, Colorado, Delaware, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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