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NCT06440408 · ClinicalTrials.gov registry record · Phase 1
Calculating Wall Shear Stress in Infant Pulmonary Veins
A Phase 1 study of Pulmonary Vein Stenosis, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06440408 is a Phase 1 study of Pulmonary Vein Stenosis that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06440408, a Phase 1 study of Pulmonary Vein Stenosis, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to better understand pediatric pulmonary vein stenosis (PVS), which is the narrowing of blood vessels that connect the lungs to the heart. PVS is a life-threatening disease without a clear cause. The investigators think patients who develop PVS have an increased Wall Shear Stress (WSS) level in the pulmonary veins, which is the force placed on the walls of the veins. This study will determine if WSS can be calculated in the pulmonary veins of infants using Ferumoxytol enhanced Cardiac Magnetic Resonance Imaging (FcMRI). If possible, the investigators aim to use FcMRI to better screen patients at risk of PVS and to help guide therapy in patients with PVS.
Conditions Studied
Interventions
- DRUG Ferumoxytol
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-09-30 |
| Est. Completion | 2027-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06440408
The ClinicalTrials.gov registry entry for NCT06440408 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pulmonary Vein Stenosis appearing as the primary indexed condition, and to 1 intervention - of which Ferumoxytol is the first listed.
NCT06440408 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06440408 about?
NCT06440408 is a clinical study titled "Calculating Wall Shear Stress in Infant Pulmonary Veins". The purpose of this study is to better understand pediatric pulmonary vein stenosis (PVS), which is the narrowing of blood vessels that connect the lungs to the heart. PVS is a life-threatening disease without a clear cause. The investigators think patients who develop PVS have an increased Wall She...
What is the current status of trial NCT06440408?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-09-30. Estimated completion is 2027-03.
What conditions does trial NCT06440408 study?
This clinical trial studies the following conditions: Pulmonary Vein Stenosis.
What interventions are being tested in trial NCT06440408?
The interventions under investigation include: Ferumoxytol (DRUG).
Who is sponsoring clinical trial NCT06440408?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06440408 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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