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NCT07123961 · ClinicalTrials.gov registry record · Phase 2
Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial
A Phase 2 study of Acute Respiratory Distress Syndrome (ARDS) and Pediatric Acute Respiratory Distress Syndrome (PARDS), sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT07123961 is a Phase 2 study of Acute Respiratory Distress Syndrome (ARDS) and Pediatric Acute Respiratory Distress Syndrome (PARDS) that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 160 participants, below the 17,715-participant average among 8 other Acute Respiratory Distress Syndrome (ARDS) trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07123961, a Phase 2 study of Acute Respiratory Distress Syndrome (ARDS) and Pediatric Acute Respiratory Distress Syndrome (PARDS), is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
Acute respiratory distress syndrome (ARDS) is a serious and potentially life-threatening lung condition that can affect children. Currently, ventilator settings commonly used in treatment are based on approaches developed for adults, and it remains unclear whether these settings are equally effective for children. Because children's bodies respond differently than adults', it is important to determine the most effective ventilator strategies specifically for pediatric patients. This study will compare two different ventilator approaches in children with ARDS to identify which method provides the greatest benefit. The findings will also help inform the design of a larger study in the future.
Conditions Studied
Interventions
- OTHER High Driving Pressure Mechanical Ventilation
- OTHER Low Driving Pressure Mechanical Ventilation
Study Locations (1)
Pennsylvania
- The Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-11-07 |
| Est. Completion | 2030-06-30 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07123961
The ClinicalTrials.gov registry entry for NCT07123961 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 160 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 17,715-participant average among 8 other Acute Respiratory Distress Syndrome (ARDS) trials with a reported enrollment target (99% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Acute Respiratory Distress Syndrome (ARDS) appearing as the primary indexed condition, and to 2 interventions - of which High Driving Pressure Mechanical Ventilation is the first listed.
NCT07123961 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07123961 about?
NCT07123961 is a clinical study titled "Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial". Acute respiratory distress syndrome (ARDS) is a serious and potentially life-threatening lung condition that can affect children. Currently, ventilator settings commonly used in treatment are based on approaches developed for adults, and it remains unclear whether these settings are equally effectiv...
What is the current status of trial NCT07123961?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 160 participants. The study started on 2025-11-07. Estimated completion is 2030-06-30.
What conditions does trial NCT07123961 study?
This clinical trial studies the following conditions: Acute Respiratory Distress Syndrome (ARDS), Pediatric Acute Respiratory Distress Syndrome (PARDS), Ventilator Management, Lung-protective Ventilation.
What interventions are being tested in trial NCT07123961?
The interventions under investigation include: High Driving Pressure Mechanical Ventilation (OTHER), Low Driving Pressure Mechanical Ventilation (OTHER).
Who is sponsoring clinical trial NCT07123961?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07123961 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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