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NCT06389994 · ClinicalTrials.gov registry record
Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy
A clinical trial of Eosinophilic Esophagitis (EoE), sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT06389994: Recruiting study of Eosinophilic Esophagitis (EoE), sponsored by Children's Hospital of Philadelphia.
NCT06389994 is a study of Eosinophilic Esophagitis (EoE) that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 75 participants, below the 119-participant average among 10 other Eosinophilic Esophagitis (EoE) trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06389994, a study of Eosinophilic Esophagitis (EoE), is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with IgE mediated food Allergy have elevated risk of eosinophilic esophagitis, and new therapies like oral immunotherapy (OIT) carry additional risk of Eosinophilic Esophagitis (EoE). The goal of this study is to investigate the Esophageal String Test (EST) as a screening tool for Eosinophilic Esophagitis (EoE) during OIT therapy. Investigators will compare the efficacy of the Esophageal String Test to symptom assessment using a validated patient reported symptom questionnaire, the Pediatric Eosinophilic Esophagitis Symptom Score (PEESS) v2.0. Investigators will utilize these tools to screen patients at their baseline visit prior to the start of OIT, then at the 3- and 6-month OIT follow-up visits.
Primary Outcome
Esophageal String Test (EST) will measure presence of eosinophilic protein. Higher score is more eosinophils.. Range is 0 to 100
Conditions Studied
Interventions
- DEVICE Esophageal String Test
Study Locations (1)
Pennsylvania
- The Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2024-04-01 |
| Est. Completion | 2026-10-01 |
What NCT06389994 shows while recruiting
NCT06389994 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 119-participant average among 10 other Eosinophilic Esophagitis (EoE) trials with a reported enrollment target (37% lower).
The record links to 1 condition, with Eosinophilic Esophagitis (EoE) appearing as the primary indexed condition, and to 1 intervention - of which Esophageal String Test is the first listed.
NCT06389994 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06389994 about?
NCT06389994 is a clinical study titled "Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy". Patients with IgE mediated food Allergy have elevated risk of eosinophilic esophagitis, and new therapies like oral immunotherapy (OIT) carry additional risk of Eosinophilic Esophagitis (EoE). The goal of this study is to investigate the Esophageal String Test (EST) as a screening tool for Eosinophi...
What is the current status of trial NCT06389994?
This trial is currently recruiting. The enrollment target is 75 participants. The study started on 2024-04-01. Estimated completion is 2026-10-01.
What conditions does trial NCT06389994 study?
This clinical trial studies the following conditions: Eosinophilic Esophagitis (EoE).
What interventions are being tested in trial NCT06389994?
The interventions under investigation include: Esophageal String Test (DEVICE).
Who is sponsoring clinical trial NCT06389994?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06389994 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06389994's enrollment target sits among peer trials
75 7th of 10 higher than 4 of 10 other Eosinophilic Esophagitis (EoE) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Eosinophilic Esophagitis (EoE) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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