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Attention Deficit Hyperactivity Disorder clinical trials
23 of 89 indexed Attention Deficit Hyperactivity Disorder trials are currently recruiting.
89 US clinical trials · 23 currently recruiting
Attention Deficit Hyperactivity Disorder is the subject of 89 registered US clinical trials on ClinicalTrials.gov, 23 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 8 of these trials.
The research picture
Attention Deficit Hyperactivity Disorder has 89 registered US clinical trials, 23 of them open to new participants right now, about 26% of the total.
- 23
- recruiting participants now
- 26%
- of trials open to enrollment
- 21
- in Phase 3–4 (later-stage)
- 8
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
89 total, page 1 of 2
Developing Brain, Impulsivity and Compulsivity
National Institute of Mental Health (NIMH)
NCT04631042
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
Massachusetts General Hospital
NCT04296604
Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation
University of Texas at Austin
NCT05802680
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Icahn School of Medicine at Mount Sinai
NCT03781752
BUILT Family Lifestyle Program for Children with ADHD
University of Illinois at Chicago
NCT05464056
Interventions for English Language Learners At-Risk for ADHD
Florida International University
NCT05918991
Efficacy of Trigeminal Nerve Stimulation for ADHD
University of California, Los Angeles
NCT05374187
R61/33 - VR Study Phase 4
Rutgers, The State University of New Jersey
NCT07169760
HOPS Study: A Conceptual Replication
Children's Hospital of Philadelphia
NCT04465708
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
National Institute of Mental Health (NIMH)
NCT05608434
Project PEAK: Early Intervention for ADHD
Lehigh University
NCT04627415
Motor Attention Training for Attention Deficit Hyperactivity Disorder (ADHD)
University of Wisconsin, Madison
NCT02688959
Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD
University of California, San Diego
NCT06180681
Mindfulness Intervention for College Students With ADHD
University of Alabama, Tuscaloo
NCT06076967
COMT Inhibition Among Individuals With Comorbid AUD/ADHD
University of Colorado, Denver
NCT03904498
A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).
Rochester Center for Behavioral Medicine
NCT06248229
Optimizing Attention and Sleep Intervention Study
University of Pittsburgh
NCT05683756
Acute Effects of Exercise in College Students With ADHD
University of Wyoming
NCT03666416
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Icahn School of Medicine at Mount Sinai
NCT03781765
ADHD PreSMA Response Inhibition Therapy
Children's Hospital Medical Center, Cincinnati
NCT06325813
Acute Effects of Stimulant Medication in College Students With ADHD
University of Wyoming
NCT03935646
Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure
University of California, Los Angeles
NCT06847165
Stimulant Effects on Disruptive Behavior
Matthew J O'Brien, PhD, BCBA-D
NCT03420339
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
National Institute of Mental Health (NIMH)
NCT00001246
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Family Navigation to Improve ADHD Treatment Adherence for Minority Children
Children's Hospital Medical Center, Cincinnati
NCT04591951
A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC
Massachusetts General Hospital
NCT04175041
Personalized Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Experiment Study
Children's Hospital Medical Center, Cincinnati
NCT06305078
Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
University of Pittsburgh
NCT06406309
Educating and Supporting Primary Care Providers in the Implementation of Evidence-based Practices for ADHD
Children's Hospital of Philadelphia
NCT02271386
Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder
Otsuka Pharmaceutical Development & Commercialization
NCT01074294
Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes
Eli Lilly and Company
NCT00510276
Study to Assess the Safety and Efficacy of NRP104 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
New River Pharmaceuticals
NCT00334880
Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD
Cephalon
NCT00315276
A Study of Pediatric Patients With Attention Deficit/Hyperactivity Disorder
Eli Lilly and Company
NCT00922636
Adult Attention Deficit Hyperactivity Disorder (ADHD) Study With Amphetamine Sulfate
Arbor Pharmaceuticals
NCT03659929
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
Hugo W. Moser Research Institute at Kennedy Krieger
NCT05927506
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
Sumitomo Pharma America
NCT00857220
STAND Community Trial
Florida International University
NCT02694939
Neurophysiological Attention Test (NAT) for Objective Assessment of Adult ADHD
Think Now Incorporated
NCT02756286
Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
Rhodes Pharmaceuticals, L.P.
NCT01239030
Investigating the Effect of Vortioxetine in Adult ADHD Patients
H. Lundbeck A/S
NCT02327013
Enhancing IEPs of Children With ADHD Using Daily Report Cards
State University of New York at Buffalo
NCT03747887
Software Treatment for Actively Reducing Severity of ADHD as Adjunctive Treatment to Stimulant
Akili Interactive Labs
NCT03649074
Parent Training for Attention Deficit Hyperactivity Disorder (ADHD) Preschoolers
NYU Langone Health
NCT01320098
Multisite Study of High School-based Treatment for Adolescents With ADHD
Ohio University
NCT04480346
A Safety and Tolerability Study of ABT-089 in Adults With Attention Deficit-Hyperactivity Disorder (ADHD)
AbbVie (prior sponsor, Abbott)
NCT00443391
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
Ironshore Pharmaceuticals and Development
NCT02493777
Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment
Cephalon
NCT00343811
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
New York State Psychiatric Institute
NCT01415440
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 12 |
| Phase 3 | 7 |
| Phase 4 | 14 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Attention Deficit Hyperactivity Disorder Trial Landscape
89 indexed Attention Deficit Hyperactivity Disorder studies · 23 recruiting (26%).
Phase mix: 21 late (III/IV) vs 19 early (I/II).
Top sponsor: Massachusetts General Hospital (8 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Attention Deficit Hyperactivity Disorder?
PlainTrial tracks 89 US clinical trials for Attention Deficit Hyperactivity Disorder, of which 23 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Attention Deficit Hyperactivity Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.