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Attention Deficit Hyperactivity Disorder
Open-data reference.
86 US clinical trials · 21 currently recruiting
Active & Recent Trials
Developing Brain, Impulsivity and Compulsivity
National Institute of Mental Health (NIMH)
NCT04631042
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
Massachusetts General Hospital
NCT04296604
Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation
University of Texas at Austin
NCT05802680
Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD
Icahn School of Medicine at Mount Sinai
NCT03781752
BUILT Family Lifestyle Program for Children with ADHD
University of Illinois at Chicago
NCT05464056
Interventions for English Language Learners At-Risk for ADHD
Florida International University
NCT05918991
R61/33 - VR Study Phase 4
Rutgers, The State University of New Jersey
NCT07169760
HOPS Study: A Conceptual Replication
Children's Hospital of Philadelphia
NCT04465708
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial
National Institute of Mental Health (NIMH)
NCT05608434
Project PEAK: Early Intervention for ADHD
Lehigh University
NCT04627415
Motor Attention Training for Attention Deficit Hyperactivity Disorder (ADHD)
University of Wisconsin, Madison
NCT02688959
Mindfulness Intervention for College Students With ADHD
University of Alabama, Tuscaloo
NCT06076967
COMT Inhibition Among Individuals With Comorbid AUD/ADHD
University of Colorado, Denver
NCT03904498
A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).
Rochester Center for Behavioral Medicine
NCT06248229
Optimizing Attention and Sleep Intervention Study
University of Pittsburgh
NCT05683756
Acute Effects of Exercise in College Students With ADHD
University of Wyoming
NCT03666416
Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk
Icahn School of Medicine at Mount Sinai
NCT03781765
ADHD PreSMA Response Inhibition Therapy
Children's Hospital Medical Center, Cincinnati
NCT06325813
Acute Effects of Stimulant Medication in College Students With ADHD
University of Wyoming
NCT03935646
Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure
University of California, Los Angeles
NCT06847165
Stimulant Effects on Disruptive Behavior
Matthew J O'Brien, PhD, BCBA-D
NCT03420339
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
National Institute of Mental Health (NIMH)
NCT00001246
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
Massachusetts General Hospital
NCT01075672
Family Navigation to Improve ADHD Treatment Adherence for Minority Children
Children's Hospital Medical Center, Cincinnati
NCT04591951
A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC
Massachusetts General Hospital
NCT04175041
Personalized Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Experiment Study
Children's Hospital Medical Center, Cincinnati
NCT06305078
Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD
University of Pittsburgh
NCT06406309
Educating and Supporting Primary Care Providers in the Implementation of Evidence-based Practices for ADHD
Children's Hospital of Philadelphia
NCT02271386
Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder
Otsuka Pharmaceutical Development & Commercialization
NCT01074294
Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes
Eli Lilly and Company
NCT00510276
Study to Assess the Safety and Efficacy of NRP104 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
New River Pharmaceuticals
NCT00334880
Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD
Cephalon
NCT00315276
A Study of Pediatric Patients With Attention Deficit/Hyperactivity Disorder
Eli Lilly and Company
NCT00922636
Adult Attention Deficit Hyperactivity Disorder (ADHD) Study With Amphetamine Sulfate
Arbor Pharmaceuticals
NCT03659929
Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD
Hugo W. Moser Research Institute at Kennedy Krieger
NCT05927506
Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia
Sumitomo Pharma America
NCT00857220
STAND Community Trial
Florida International University
NCT02694939
Neurophysiological Attention Test (NAT) for Objective Assessment of Adult ADHD
Think Now Incorporated
NCT02756286
Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
Rhodes Pharmaceuticals, L.P.
NCT01239030
Investigating the Effect of Vortioxetine in Adult ADHD Patients
H. Lundbeck A/S
NCT02327013
Enhancing IEPs of Children With ADHD Using Daily Report Cards
State University of New York at Buffalo
NCT03747887
Software Treatment for Actively Reducing Severity of ADHD as Adjunctive Treatment to Stimulant
Akili Interactive Labs
NCT03649074
Parent Training for Attention Deficit Hyperactivity Disorder (ADHD) Preschoolers
NYU Langone Health
NCT01320098
Multisite Study of High School-based Treatment for Adolescents With ADHD
Ohio University
NCT04480346
A Safety and Tolerability Study of ABT-089 in Adults With Attention Deficit-Hyperactivity Disorder (ADHD)
AbbVie (prior sponsor, Abbott)
NCT00443391
A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
Ironshore Pharmaceuticals and Development
NCT02493777
Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment
Cephalon
NCT00343811
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
New York State Psychiatric Institute
NCT01415440
Helping College Students With ADHD Lead Healthier Lifestyles
University of Maryland, College Park
NCT02829970
Bupropion for ADHD in Adolescents With Substance Use Disorder
University of Colorado, Denver
NCT00936299
New Technologies to Help Manage ADHD
Children's Hospital Medical Center, Cincinnati
NCT02390791
Cognitive ADHD Videogame Exploratory Study
Akili Interactive Labs
NCT01943539
dHealth Solution for Improving Parent Adherence to Behavioral Treatment for ADHD
University of California, San Francis
NCT04025814
Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials
Massachusetts General Hospital
NCT01063153
Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
Denver Health and Hospital Authority
NCT00399763
PART A: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and With mGluR Mutations
Aevi Genomic Medicine, LLC, a Cerecor company
NCT03265119
Mindfulness-Based ADHD Treatment for Children: a Feasibility Study
Yale University
NCT04737512
A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall
NYU Langone Health
NCT00468143
Safety and Efficacy of Switching From a Stimulant Medication to Atomoxetine in Children and Adolescents With ADHD
Eli Lilly and Company
NCT00485875
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children
NYU Langone Health
NCT04108273
Naturalistic Substitution of Concerta in Adult Subject With ADHD Receiving Immediate Release Methylphenidate
Massachusetts General Hospital
NCT00302406
Mindful Parenting and Parent Training Program Study
New York University
NCT03796663
Brain Plasticity Underlying Acquisition of New Organizational Skills in Children-R61 Phase
NYU Langone Health
NCT03148782
Eye Tracking as a Predictor of Methylphenidate Response in Autism With ADHD
Children's Hospital Medical Center, Cincinnati
NCT02874690
Effectiveness and Duration of Effect of Open Treatment in Attention Deficit Hyperactivity Disorder (ADHD) Patients Treated With Lisdexamfetamine Dimesylate(Vyvanse)
NYU Langone Health
NCT01070394
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
University of Nebraska
NCT03730194
Attention-Deficit/Hyperactivity Disorder (ADHD) Brain Activity Changes to Psychostimulants
Hartford Hospital
NCT01310439
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
Massachusetts General Hospital
NCT04569058
Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT
NYU Langone Health
NCT02635035
Study of Medication Patch to Treat Children Ages 6-12 With ADHD
Massachusetts General Hospital
NCT00586157
Text Messaging Adherence to Stimulant Medication
Massachusetts General Hospital
NCT01967485
Mobile Behavioral Parent Training for Childhood ADHD: A Micro-randomized Trial
Florida International University
NCT06012851
A Safety and Effectiveness Study of JNJ-31001074 in Adults With Attention-Deficit/Hyperactivity Disorder.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
NCT00566449
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
University of Cincinnati
NCT00414921
Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory
Children's Hospital of Philadelphia
NCT00530257
Electroencephalogram (EEG) Study of Inattention Following Treatment With AKL-T01
Akili Interactive Labs
NCT03844269
Task-Based Grounding Program
Dartmouth-Hitchcock Medical Center
NCT04648553
Effects of Exercise Intensity on ADHD Symptoms
Kent State University
NCT06753253
Effectiveness Study of Videoconferencing on Teaching Parent Training Skills to Parents of Children With Attention Deficit Hyperactivity Disorder (ADHD)
University of California, Davis
NCT01161719
GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs
CogCubed
NCT01808066
Study of Droxidopa Treatment in Adults With Attention Deficit Hyperactivity Disorder With Co-administration of Carbidopa
Chelsea Therapeutics
NCT00983814
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices in Adults
CogCubed
NCT02127931
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
University of Oklahoma
NCT00541346
Medication Integration in Treatment of Comorbid Adolescent Substance Users/Attention Deficit Hyperactivity Disorder
The National Center on Addiction and Substance Abuse at Columbia University
NCT01369459
Healing Minds: Biofeedback and Breathing Practices in Children and Adolescents With ADHD
Hoskinson Health and Wellness Clinic
NCT06648252
Effects of L-theanine and Caffeine on Attention and Attention-related Brain Activity of Children With Attention Deficit Hyperactivity Disorder
Texas Tech University
NCT03533556
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 12 |
| Phase 3 | 7 |
| Phase 4 | 14 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Attention Deficit Hyperactivity Disorder Trial Landscape
ClinicalTrials.gov lists 86 US studies indexed under Attention Deficit Hyperactivity Disorder, and 21 of those are currently open to recruitment — roughly 24% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Attention Deficit Hyperactivity Disorder shows 21 late-stage studies (Phase 3 and Phase 4 combined) alongside 18 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Attention Deficit Hyperactivity Disorder is led by Massachusetts General Hospital with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 86 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Attention Deficit Hyperactivity Disorder?
PlainTrial tracks 86 US clinical trials for Attention Deficit Hyperactivity Disorder, of which 21 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Attention Deficit Hyperactivity Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.