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ClinicalTrials.gov 29 recruiting now full pipeline #130 of 28,707 conditions

Attention Deficit Hyperactivity Disorder: full-pipeline trial registry

29 of 103 indexed Attention Deficit Hyperactivity Disorder trials are currently recruiting.

Corpus placement: #130 of 28,707 conditions by registered trial count.

103 US clinical trials · 29 currently recruiting · #130 of 28,707 conditions by registered trial count

Attention Deficit Hyperactivity Disorder: 103 US clinical trials tracked, 29 recruiting.

Attention Deficit Hyperactivity Disorder is the subject of 103 registered US clinical trials on ClinicalTrials.gov, 29 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 24 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 9 of these trials.

Enrollment posture brief

Registry condition attention-deficit-hyperactivity-disorder

OPEN 29 | RECR 28% | LATE 27 | EARLY 24 | RANK #130 | SPON 9

Nearest open-share peer: Astigmatism (28% recruiting · 32 trials)

Amyotrophic Lateral Sclerosi45.6%Mantle Cell Lymphoma44.7%Chronic Kidney Disease31.1%Attention Deficit Hypera (th…28%Metabolic Syndrome26.9%
Open-enrollment share among volume-matched conditions near Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder lists 29 open slots (28% of 103 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Attention Deficit Hyperactivity Disorder on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Attention Deficit Hyperactivity Disorder is recruiting below its size-band peers.

    29 of 103 indexed trials (28.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Attention Deficit Hyperactivity Disorder trials is spread across many organizations.

    Massachusetts General Hospital accounts for 9 of 103 trials (8.7%). 64 distinct sponsors appear on at least one study for this condition label.

  3. Typical Attention Deficit Hyperactivity Disorder enrolment sits around 71 participants.

    Median target enrolment is 71 among the 103 trials that report a genuine target (sentinel values excluded). 56 of those (54.4%) plan for fewer than 100 participants.

  4. Attention Deficit Hyperactivity Disorder research is mostly interventional.

    97 interventional and 6 observational studies make up this index (94.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 216Phase 310Phase 417

Open and recent trials

103 total, page 1 of 3

RECRUITING 1,100 participants

Developing Brain, Impulsivity and Compulsivity

National Institute of Mental Health (NIMH)

NCT04631042

RECRUITING NA 600 participants

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Massachusetts General Hospital

NCT04296604

RECRUITING NA 500 participants

Neurocognitive Effects of Non-Invasive Near-Infrared Light Stimulation

University of Texas at Austin

NCT05802680

RECRUITING Phase 4 500 participants

Carboxylesterase 1 Genetic Variation and Methylphenidate in ADHD

Icahn School of Medicine at Mount Sinai

NCT03781752

RECRUITING NA 316 participants

BUILT Family Lifestyle Program for Children with ADHD

University of Illinois at Chicago

NCT05464056

RECRUITING NA 300 participants

Interventions for English Language Learners At-Risk for ADHD

Florida International University

NCT05918991

RECRUITING Phase 4 286 participants

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

Supernus Pharmaceuticals

NCT04781140

RECRUITING NA 280 participants

Efficacy of Trigeminal Nerve Stimulation for ADHD

University of California, Los Angeles

NCT05374187

RECRUITING Phase 4 252 participants

R61/33 - VR Study Phase 4

Rutgers, The State University of New Jersey

NCT07169760

RECRUITING NA 240 participants

HOPS Study: A Conceptual Replication

Children's Hospital of Philadelphia

NCT04465708

RECRUITING Phase 1 219 participants

Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Pilot Phase I and Randomized Controlled Phase II Trial

National Institute of Mental Health (NIMH)

NCT05608434

RECRUITING NA 180 participants

Project PEAK: Early Intervention for ADHD

Lehigh University

NCT04627415

RECRUITING NA 145 participants

Motor Attention Training for Attention Deficit Hyperactivity Disorder (ADHD)

University of Wisconsin, Madison

NCT02688959

RECRUITING NA 144 participants

Enhancing Team Effectiveness for a Collaborative School-based Intervention for ADHD

University of California, San Diego

NCT06180681

RECRUITING NA 100 participants

Mindfulness Intervention for College Students With ADHD

University of Alabama, Tuscaloo

NCT06076967

RECRUITING Phase 2 76 participants

The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder

University of Arkansas, Fayetteville

NCT06115603

RECRUITING Phase 2 62 participants

COMT Inhibition Among Individuals With Comorbid AUD/ADHD

University of Colorado, Denver

NCT03904498

RECRUITING Phase 4 50 participants

A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).

Rochester Center for Behavioral Medicine

NCT06248229

RECRUITING NA 50 participants

Optimizing Attention and Sleep Intervention Study

University of Pittsburgh

NCT05683756

RECRUITING NA 48 participants

Acute Effects of Exercise in College Students With ADHD

University of Wyoming

NCT03666416

RECRUITING Phase 4 44 participants

Stimulant vs. Non-stimulant Treatments and Reward Processing in Drug-naive Youth at SUD Risk

Icahn School of Medicine at Mount Sinai

NCT03781765

RECRUITING NA 40 participants

ADHD PreSMA Response Inhibition Therapy

Children's Hospital Medical Center, Cincinnati

NCT06325813

RECRUITING Phase 2 40 participants

Acute Effects of Stimulant Medication in College Students With ADHD

University of Wyoming

NCT03935646

RECRUITING NA 36 participants

A Pilot Study of a Remote ADHD Monitoring Program

IDeA States Pediatric Clinical Trials Network

NCT06743425

RECRUITING NA 30 participants

Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

University of California, Los Angeles

NCT06847165

RECRUITING 30 participants

Focus Groups in Ethnically and Racially Diverse Families

Oregon Health and Science University

NCT05930886

RECRUITING NA 30 participants

Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)

Oregon Health and Science University

NCT06133231

RECRUITING Phase 4 30 participants

An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening

NYU Langone Health

NCT06577779

RECRUITING Phase 4 10 participants

Stimulant Effects on Disruptive Behavior

Matthew J O'Brien, PhD, BCBA-D

NCT03420339

ACTIVE NOT RECRUITING 4,274 participants

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

National Institute of Mental Health (NIMH)

NCT00001246

ACTIVE NOT RECRUITING Phase 3 1,400 participants

Open-label Study to Evaluate Long-term Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule)

Supernus Pharmaceuticals

NCT02736656

ACTIVE NOT RECRUITING Phase 3 680 participants

A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder.

Otsuka Pharmaceutical Development & Commercialization

NCT05279313

ACTIVE NOT RECRUITING NA 250 participants

Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals

Massachusetts General Hospital

NCT01075672

ACTIVE NOT RECRUITING NA 108 participants

Family Navigation to Improve ADHD Treatment Adherence for Minority Children

Children's Hospital Medical Center, Cincinnati

NCT04591951

ACTIVE NOT RECRUITING NA 104 participants

A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC

Massachusetts General Hospital

NCT04175041

ACTIVE NOT RECRUITING NA 30 participants

Personalized Attention-Deficit/Hyperactivity Disorder (ADHD) Medication Experiment Study

Children's Hospital Medical Center, Cincinnati

NCT06305078

ACTIVE NOT RECRUITING NA 30 participants

Settling Down for Sleep in ADHD: The Impact of Sensory and Arousal Systems on Sleep in ADHD

University of Pittsburgh

NCT06406309

COMPLETED NA 895 participants

Educating and Supporting Primary Care Providers in the Implementation of Evidence-based Practices for ADHD

Children's Hospital of Philadelphia

NCT02271386

COMPLETED Phase 2 740 participants

Study of the Safety and Efficacy of OPC-34712 as a Complementary Therapy in the Treatment of Adult Attention Deficit/Hyperactivity Disorder

Otsuka Pharmaceutical Development & Commercialization

NCT01074294

COMPLETED Phase 3 725 participants

Efficacy and Safety Study of Methylphenidate Hydrochloride Extended Release in Adults With Childhood-onset Attention Deficit/Hyperactivity Disorder (ADHD)

Novartis Pharmaceuticals

NCT01259492

COMPLETED Phase 4 445 participants

Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes

Eli Lilly and Company

NCT00510276

COMPLETED Phase 3 420 participants

Study to Assess the Safety and Efficacy of NRP104 in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

New River Pharmaceuticals

NCT00334880

COMPLETED Phase 2 370 participants

Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD

Cephalon

NCT00315276

COMPLETED Phase 2 340 participants

A Study of Pediatric Patients With Attention Deficit/Hyperactivity Disorder

Eli Lilly and Company

NCT00922636

COMPLETED Phase 3 320 participants

Adult Attention Deficit Hyperactivity Disorder (ADHD) Study With Amphetamine Sulfate

Arbor Pharmaceuticals

NCT03659929

COMPLETED 312 participants

Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05927506

COMPLETED Phase 3 304 participants

Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia

Sumitomo Pharma America

NCT00857220

COMPLETED Phase 2 295 participants

A Study of TD-9855 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)

Theravance Biopharma

NCT01458340

COMPLETED NA 278 participants

STAND Community Trial

Florida International University

NCT02694939

COMPLETED 258 participants

Neurophysiological Attention Test (NAT) for Objective Assessment of Adult ADHD

Think Now Incorporated

NCT02756286

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Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 16
Phase 3 10
Phase 4 17

Named interventions

Most-linked intervention names on Attention Deficit Hyperactivity Disorder records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
20 trials
Methylphenidate Drug
4 trials
Placebo Other
3 trials
Methylphenidate Transdermal System Drug
2 trials
ABT-089 Drug
2 trials
AKL-T01 Device
2 trials
Lisdexamfetamine Drug
2 trials
Daily Report Card Behavioral
2 trials

US sites by state

Facility locations filed on Attention Deficit Hyperactivity Disorder trials. A trial with sites in several states counts in each.

New York 25 trials
California 25 trials
Florida 23 trials
Ohio 16 trials
Massachusetts 15 trials
Pennsylvania 13 trials
Texas 12 trials
Arkansas 11 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Attention Deficit Hyperactivity Disorder page

103 registered trials, 29 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 29 Attention Deficit Hyperactivity Disorder trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Massachusetts General Hospital sponsors the most Attention Deficit Hyperactivity Disorder trials on record, review their full trial history before evaluating a specific study. See Massachusetts General Hospital's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Attention Deficit Hyperactivity Disorder condition card totals 103 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.