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NCT05555550 · ClinicalTrials.gov registry record · Early Phase 1
Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG
A Early Phase 1 study of Glioma and Low Grade Glioma, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05555550 is a Early Phase 1 study of Glioma and Low Grade Glioma that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 30 participants, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05555550, a Early Phase 1 study of Glioma and Low Grade Glioma, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 18F-Fluciclovine PET-MRI will be performed prior to initiation of therapy for LGG, and then 3 months, and 1 year after starting therapy. Changes in 18F-Fluciclovine uptake will be compared to changes in MRI measurements at 3 months and 1 year as compared to baseline.
Conditions Studied
Interventions
- DRUG 18F-Fluciclovine
Study Locations (1)
Pennsylvania
- The Children s Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-12-29 |
| Est. Completion | 2027-09 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05555550
The ClinicalTrials.gov registry entry for NCT05555550 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (86% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Glioma appearing as the primary indexed condition, and to 1 intervention - of which 18F-Fluciclovine is the first listed.
NCT05555550 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05555550 about?
NCT05555550 is a clinical study titled "Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG". The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 18F-Fluciclovine PET-MRI will be performed prior to initiation of therapy for LGG, and then 3 months, and 1 year after starting therapy. Chang...
What is the current status of trial NCT05555550?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2025-12-29. Estimated completion is 2027-09.
What conditions does trial NCT05555550 study?
This clinical trial studies the following conditions: Glioma, Low Grade Glioma, Glioma, Malignant, Low Grade Glioma of Brain, Glioma Intracranial.
What interventions are being tested in trial NCT05555550?
The interventions under investigation include: 18F-Fluciclovine (DRUG).
Who is sponsoring clinical trial NCT05555550?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05555550 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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