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NCT07255248 · ClinicalTrials.gov registry record · Phase 4

Hoffa's Fat Pad Impingement (HFPI)

A Phase 4 study of Hoffa's Fat Pad Impingement, sponsored by Boston Children's Hospital.

Recruiting
Registry status
Phase 4
Development phase
62
Enrollment target
1
Study location

NCT07255248: Recruiting Phase 4 study of Hoffa's Fat Pad Impingement, sponsored by Boston Children's Hospital.

NCT07255248 is a Phase 4 study of Hoffa's Fat Pad Impingement that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 62 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07255248, a Phase 4 study of Hoffa's Fat Pad Impingement, is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
Phase 4
Development phase
62 participants
Enrollment target
1
Study location

Study Summary

The aim of the study is to investigate treatment outcomes for refractory anterior knee pain due to Hoffa's Fat Pad Impingement (HFPI) in young female athletes. Specifically, the study team will study pediatric female athletes with HFPI, and treatment outcomes of US-guided Hoffa's Fat Pad (HFP) corticosteroid injection compared to standard care (physical therapy, bracing, no injection) and saline injection. There will be two arms in this study, 1, a corticosteroid injection and physical therapy and 2, physical therapy and a saline injection. The intent of this study is to measure treatment outcomes, and the research team is not looking at the safety and effectiveness of the lidocaine-methylprednisolone mixture.

Primary Outcome

The IKDC is a patient-reported outcome measure on a 0-100 scale assessing knee function, symptoms, and sports activities, with higher scores indicating better function, and a lower score indicating low function.

Interventions

  • DRUG methylprednisolone acetate and lidocaine
  • DRUG Saline injection (Octreotide LAR placebo)

Study Locations (1)

Massachusetts

  • Boston Children's Hospital - Norwood

Trial Details

FieldValue
Enrollment Target 62 participants
Start Date 2026-03-01
Est. Completion 2028-01-02
Phase Phase 4
Boston Children's Hospital

462 total trials

What NCT07255248 shows while recruiting

NCT07255248 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (88% lower).

The record links to 1 condition, with Hoffa's Fat Pad Impingement appearing as the primary indexed condition, and to 2 interventions - of which methylprednisolone acetate and lidocaine is the first listed.

NCT07255248 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07255248 about?

NCT07255248 is a clinical study titled "Hoffa's Fat Pad Impingement (HFPI)". The aim of the study is to investigate treatment outcomes for refractory anterior knee pain due to Hoffa's Fat Pad Impingement (HFPI) in young female athletes. Specifically, the study team will study pediatric female athletes with HFPI, and treatment outcomes of US-guided Hoffa's Fat Pad (HFP) corti...

What is the current status of trial NCT07255248?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 62 participants. The study started on 2026-03-01. Estimated completion is 2028-01-02.

What conditions does trial NCT07255248 study?

This clinical trial studies the following conditions: Hoffa's Fat Pad Impingement.

What interventions are being tested in trial NCT07255248?

The interventions under investigation include: methylprednisolone acetate and lidocaine (DRUG), Saline injection (Octreotide LAR placebo) (DRUG).

Who is sponsoring clinical trial NCT07255248?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07255248 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT07255248's enrollment target sits among peer trials

62 1110th of 2000 higher than 883 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07255248, the US trial registry maintained by the National Library of Medicine. NCT07255248 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.