Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05455359 · ClinicalTrials.gov registry record · Phase 4
Gastrointestinal Dysmotility on Aspiration Risk
A Phase 4 study of Gastro Esophageal Reflux and Aspiration Pneumonia, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT05455359 is a Phase 4 study of Gastro Esophageal Reflux and Aspiration Pneumonia that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 120 participants, below the 12,929-participant average among 7 other Gastro Esophageal Reflux trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05455359, a Phase 4 study of Gastro Esophageal Reflux and Aspiration Pneumonia, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment. The investigators are conducting a ten week cross over study comparing prucalopride to famotidine for the treatment of aspiration-associated symptoms.
Conditions Studied
Interventions
- DRUG Famotidine
- DRUG Prucalopride
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-02-13 |
| Est. Completion | 2027-05-31 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05455359
The ClinicalTrials.gov registry entry for NCT05455359 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,929-participant average among 7 other Gastro Esophageal Reflux trials with a reported enrollment target (99% lower). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Gastro Esophageal Reflux appearing as the primary indexed condition, and to 2 interventions - of which Famotidine is the first listed.
NCT05455359 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05455359 about?
NCT05455359 is a clinical study titled "Gastrointestinal Dysmotility on Aspiration Risk". The hypothesis of this study is that esophageal and gastric dysmotility increase the risk of developing aspiration-associated symptoms in children with neurologic impairment. The investigators are conducting a ten week cross over study comparing prucalopride to famotidine for the treatment of aspira...
What is the current status of trial NCT05455359?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 120 participants. The study started on 2025-02-13. Estimated completion is 2027-05-31.
What conditions does trial NCT05455359 study?
This clinical trial studies the following conditions: Gastro Esophageal Reflux, Aspiration Pneumonia, Esophageal Motility Disorders, Gastric Motor Dysfunction.
What interventions are being tested in trial NCT05455359?
The interventions under investigation include: Famotidine (DRUG), Prucalopride (DRUG).
Who is sponsoring clinical trial NCT05455359?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05455359 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gastro Esophageal Reflux
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Esophageal and Gastric Registry and Biorepository
RECRUITING
-
Clinical Utility of WATS3D: A 5-Year Prospective Study
RECRUITING
-
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
RECRUITING
-
Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)
RECRUITING · NA
-
Efficacy Of Hiatal Closure For GERD
RECRUITING
-
Transpyloric Feeding for Prevention of Micro-aspiration
ACTIVE NOT RECRUITING
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.