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NCT06553976 · ClinicalTrials.gov registry record
Spastic Paraplegia - Centers of Excellence Research Network
A clinical trial of Neuromuscular Diseases and Primary Lateral Sclerosis, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- 100
- Enrollment target
- 11
- Study locations
NCT06553976 is a study of Neuromuscular Diseases and Primary Lateral Sclerosis that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 100 participants, below the 125-participant average among 15 other Neuromuscular Diseases trials with a reported enrollment target (20% lower). The trial reports 11 study locations across 8 states.
The verdict
NCT06553976, a study of Neuromuscular Diseases and Primary Lateral Sclerosis, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 11
- Study locations
Study Summary
The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diagnosis, and treatment of hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS). Aims of the consortium are to a) perform natural history studies of HSP subtypes, b) discover and validate biomarkers and clinician- and patient-reported outcome measures, c) uncover HSP's molecular pathophysiology and develop rational therapeutic targets, and d) perform sufficiently powered clinical trials. The current pilot study is aimed at enrolling 100 individuals with hereditary spastic paraplegia type 4 (SPG4) or hereditary spastic paraplegia type 5A (SPG5A).
Conditions Studied
Study Locations (11)
Massachusetts
- Boston Children's Hospital - Boston
- Massachusetts General Hospital - Boston
Texas
- Scottish Rite for Children - Dallas
- Texas Children's Hospital - Houston
Washington
- Seattle Children's Hospital - Seattle
- University of Washington School of Medicine - Seattle
Florida
- University of Miami Miller School of Medicine - Miami
Iowa
- University of Iowa Carver College of Medicine - Iowa City
Michigan
- University of Michigan School of Medicine - Ann Arbor
New York
- Columbia University - Irving Medical Center - New York
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-06-04 |
| Est. Completion | 2027-06-04 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06553976
The ClinicalTrials.gov registry entry for NCT06553976 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 125-participant average among 15 other Neuromuscular Diseases trials with a reported enrollment target (20% lower). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 9 conditions, with Neuromuscular Diseases appearing as the primary indexed condition, and to 0 interventions.
NCT06553976 reports 11 study locations spanning 8 distinct geographic areas - top geographies include Massachusetts, Texas, Washington.
Frequently Asked Questions
What is clinical trial NCT06553976 about?
NCT06553976 is a clinical study titled "Spastic Paraplegia - Centers of Excellence Research Network". The Spastic Paraplegia - Centers of Excellence Research Network (SP-CERN) is a collaborative research consortium dedicated to advancing the understanding, diagnosis, and treatment of hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS). Aims of the consortium are to a) perform nat...
What is the current status of trial NCT06553976?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2024-06-04. Estimated completion is 2027-06-04.
What conditions does trial NCT06553976 study?
This clinical trial studies the following conditions: Neuromuscular Diseases, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Early Onset Hereditary Spastic Paraplegia, SPG4.
Who is sponsoring clinical trial NCT06553976?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06553976 being conducted?
This trial has 11 study locations across Florida, Iowa, Massachusetts, Michigan, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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