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NCT04190524 · ClinicalTrials.gov registry record · NA

Sonographic Assessment of Cricoid Pressure

A NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia, sponsored by Boston Children's Hospital.

Recruiting
Registry status
NA
Development phase
45
Enrollment target
1
Study location

NCT04190524: Recruiting NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia, sponsored by Boston Children's Hospital.

NCT04190524 is a NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 45 participants, below the 26,549-participant average among 10 other Intubation Complication trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04190524, a NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia, is actively recruiting participants, sponsored by Boston Children's Hospital.

RECRUITING
Registry status
NA
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

Examining the effectiveness of cricoid pressure using ultrasound imaging. Pulmonary aspiration of gastric contents during tracheal intubation, although rare in pediatrics, is a potentially catastrophic complication of anesthesia. Cricoid pressure is applied during rapid sequence induction to occlude the esophagus and prevent aspiration of gastric contents. Accumulating evidence in adults suggests that cricoid pressure often is not effective, either because the esophagus normally lies lateral to the cricoid cartilage, or because downward pressure on the cricoid cartilage laterally displaces (rather than compresses) the esophagus. The investigator proposes to examine the effectiveness of cricoid pressure in children in the peri-operative setting using non-invasive ultrasound imaging. Using this approach, the investigator will investigate the normal anatomical relationship of the esophagus and the cricoid cartilage, as well as how cricoid pressures influences this relationship. Further, the investigator will examine whether alternatives to downward cricoid pressure, such as laterally directed pressure, are more effective at occluding the esophagus.

Primary Outcome

1. To sonographically assess the diameter of the esophagus before and after application of conventional cricoid pressure 2. To sonographically asses the diameter of the esophagus before and after application of left lateral paralaryngeal pressure

Interventions

  • OTHER Application of cricoid pressure
  • OTHER Application of Left lateral paratracheal pressure

Study Locations (1)

Massachusetts

  • Boston Children's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-09
Est. Completion 2026-09
Phase NA
Boston Children's Hospital

462 total trials

What NCT04190524 shows while recruiting

NCT04190524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 26,549-participant average among 10 other Intubation Complication trials with a reported enrollment target (100% lower).

The record links to 2 conditions, with Intubation Complication appearing as the primary indexed condition, and to 2 interventions - of which Application of cricoid pressure is the first listed.

NCT04190524 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04190524 about?

NCT04190524 is a clinical study titled "Sonographic Assessment of Cricoid Pressure". Examining the effectiveness of cricoid pressure using ultrasound imaging. Pulmonary aspiration of gastric contents during tracheal intubation, although rare in pediatrics, is a potentially catastrophic complication of anesthesia. Cricoid pressure is applied during rapid sequence induction to occlude...

What is the current status of trial NCT04190524?

This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2025-09. Estimated completion is 2026-09.

What conditions does trial NCT04190524 study?

This clinical trial studies the following conditions: Intubation Complication, Aspiration; Gastric Contents, Anesthesia.

What interventions are being tested in trial NCT04190524?

The interventions under investigation include: Application of cricoid pressure (OTHER), Application of Left lateral paratracheal pressure (OTHER).

Who is sponsoring clinical trial NCT04190524?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04190524 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Intubation Complication

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04190524's enrollment target sits among peer trials

45 10th of 10 higher than 1 of 10 other Intubation Complication trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Intubation Complication trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04190524, the US trial registry maintained by the National Library of Medicine. NCT04190524 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.