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NCT04190524 · ClinicalTrials.gov registry record · NA
Sonographic Assessment of Cricoid Pressure
A NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia, sponsored by Boston Children's Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT04190524 is a NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia that is actively recruiting participants, run by Boston Children's Hospital. The registered enrollment target is 45 participants, below the 26,549-participant average among 10 other Intubation Complication trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04190524, a NA study of Intubation Complication and Aspiration; Gastric Contents, Anesthesia, is actively recruiting participants, sponsored by Boston Children's Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
Examining the effectiveness of cricoid pressure using ultrasound imaging. Pulmonary aspiration of gastric contents during tracheal intubation, although rare in pediatrics, is a potentially catastrophic complication of anesthesia. Cricoid pressure is applied during rapid sequence induction to occlude the esophagus and prevent aspiration of gastric contents. Accumulating evidence in adults suggests that cricoid pressure often is not effective, either because the esophagus normally lies lateral to the cricoid cartilage, or because downward pressure on the cricoid cartilage laterally displaces (rather than compresses) the esophagus. The investigator proposes to examine the effectiveness of cricoid pressure in children in the peri-operative setting using non-invasive ultrasound imaging. Using this approach, the investigator will investigate the normal anatomical relationship of the esophagus and the cricoid cartilage, as well as how cricoid pressures influences this relationship. Further, the investigator will examine whether alternatives to downward cricoid pressure, such as laterally directed pressure, are more effective at occluding the esophagus.
Conditions Studied
Interventions
- OTHER Application of cricoid pressure
- OTHER Application of Left lateral paratracheal pressure
Study Locations (1)
Massachusetts
- Boston Children's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2025-09 |
| Est. Completion | 2026-09 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04190524
The ClinicalTrials.gov registry entry for NCT04190524 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 26,549-participant average among 10 other Intubation Complication trials with a reported enrollment target (100% lower). The listed sponsor is Boston Children's Hospital, which has 462 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Intubation Complication appearing as the primary indexed condition, and to 2 interventions - of which Application of cricoid pressure is the first listed.
NCT04190524 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04190524 about?
NCT04190524 is a clinical study titled "Sonographic Assessment of Cricoid Pressure". Examining the effectiveness of cricoid pressure using ultrasound imaging. Pulmonary aspiration of gastric contents during tracheal intubation, although rare in pediatrics, is a potentially catastrophic complication of anesthesia. Cricoid pressure is applied during rapid sequence induction to occlude...
What is the current status of trial NCT04190524?
This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2025-09. Estimated completion is 2026-09.
What conditions does trial NCT04190524 study?
This clinical trial studies the following conditions: Intubation Complication, Aspiration; Gastric Contents, Anesthesia.
What interventions are being tested in trial NCT04190524?
The interventions under investigation include: Application of cricoid pressure (OTHER), Application of Left lateral paratracheal pressure (OTHER).
Who is sponsoring clinical trial NCT04190524?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04190524 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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