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NCT04851678 · ClinicalTrials.gov registry record
Longitudinal Impact of Stressors in Adults With Tourette Syndrome
A clinical trial of Tourette Syndrome, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- 140
- Enrollment target
- 1
- Study location
NCT04851678: Recruiting study of Tourette Syndrome, sponsored by Vanderbilt University Medical Center.
NCT04851678 is a study of Tourette Syndrome that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 140 participants, above the 82-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (71% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04851678, a study of Tourette Syndrome, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
The Investigators propose a two-year, longitudinal pilot study of TS adults (\>18) to determine impact of lifetime environmental stress exposure on tic severity, psychiatric comorbidity severity, and health-related quality of life (HRQOL).
Primary Outcome
Semi-structured, clinician-administered interview to assess tic severity. Total tic scores are a composite of motor tic scores (0-25) and phonic tic scores (0-25) based on 5 dimensions of tic severity: number, frequency, intensity, complexity, and interference. Total tic scores range from 0-50. Higher scores indicate great tic severity. The YGTSS is the gold-standard clinical rating scale for tic severity.
Conditions Studied
Interventions
- OTHER None - observational study
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2021-09-30 |
| Est. Completion | 2027-06-30 |
What NCT04851678 shows while recruiting
NCT04851678 is an observational study that tracks outcomes without assigning an intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, above the 82-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (71% higher).
The record links to 1 condition, with Tourette Syndrome appearing as the primary indexed condition, and to 1 intervention - of which None - observational study is the first listed.
NCT04851678 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT04851678 about?
NCT04851678 is a clinical study titled "Longitudinal Impact of Stressors in Adults With Tourette Syndrome". The Investigators propose a two-year, longitudinal pilot study of TS adults (\>18) to determine impact of lifetime environmental stress exposure on tic severity, psychiatric comorbidity severity, and health-related quality of life (HRQOL).
What is the current status of trial NCT04851678?
This trial is currently recruiting. The enrollment target is 140 participants. The study started on 2021-09-30. Estimated completion is 2027-06-30.
What conditions does trial NCT04851678 study?
This clinical trial studies the following conditions: Tourette Syndrome.
What interventions are being tested in trial NCT04851678?
The interventions under investigation include: None - observational study (OTHER).
Who is sponsoring clinical trial NCT04851678?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04851678 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tourette Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04851678's enrollment target sits among peer trials
140 9th of 33 higher than 25 of 33 other Tourette Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tourette Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Sensorimotor and Psychosocial Trajectories in Adolescents With Tic Disorder
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-
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-
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Trajectories of Change in Tourette Syndrome
RECRUITING · NA
-
Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
RECRUITING · NA
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