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ClinicalTrials.gov 9 recruiting now official registry

Anatomic Stage IIA Breast Cancer AJCC v8 clinical trials

9 of 34 indexed Anatomic Stage IIA Breast Cancer AJCC v8 trials are currently recruiting.

34 US clinical trials · 9 currently recruiting

Anatomic Stage IIA Breast Cancer AJCC v8 is the subject of 34 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 9 of these trials.

The research picture

Anatomic Stage IIA Breast Cancer AJCC v8 has 34 registered US clinical trials, 9 of them open to new participants right now, about 26% of the total.

9
recruiting participants now
26%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
9
top sponsor: M.D. Anderson Cancer Center
Phase 16Phase 26Phase 31

Active & Recent Trials

34 total, page 1 of 1

RECRUITING 250 participants

Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors

University of Southern California

NCT07259304

RECRUITING Early Phase 1 50 participants

Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT05417308

RECRUITING NA 40 participants

A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment

University of Alabama at Birmingham

NCT05243056

RECRUITING NA 30 participants

Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors

University of Alabama at Birmingham

NCT05452681

RECRUITING NA 27 participants

Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Stage I-III Early Stage Breast Cancer

Emory University

NCT05368428

RECRUITING Phase 2 20 participants

Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction

Mayo Clinic

NCT06153836

RECRUITING Phase 1 18 participants

Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer

Emory University

NCT06324240

RECRUITING Phase 1 18 participants

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT05319873

RECRUITING NA 15 participants

Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

M.D. Anderson Cancer Center

NCT02918474

ACTIVE NOT RECRUITING Phase 2 2,175 participants

CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

ECOG-ACRIN Cancer Research Group

NCT04266249

ACTIVE NOT RECRUITING 1,410 participants

Infertility Survey Among Reproductive Age Women With Gynecological and Breast Cancer

M.D. Anderson Cancer Center

NCT04678414

ACTIVE NOT RECRUITING 1,336 participants

Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer

SWOG Cancer Research Network

NCT03939481

ACTIVE NOT RECRUITING Phase 2 1,100 participants

Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer

M.D. Anderson Cancer Center

NCT01334021

ACTIVE NOT RECRUITING Phase 3 1,056 participants

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Alliance for Clinical Trials in Oncology

NCT04457596

ACTIVE NOT RECRUITING NA 543 participants

Improving Patient-Centered Communication in Breast Cancer Through Patient and Provider Interventions

Alliance for Clinical Trials in Oncology

NCT04549571

ACTIVE NOT RECRUITING NA 400 participants

Web-Based Symptom Monitoring and Self-Management Portal (YES) for Adolescent and Young Adult Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT04906200

ACTIVE NOT RECRUITING NA 332 participants

A Text-based Intervention in Improving Adherence to Hormone Therapy in Patients With Stage I-III Hormone Receptor Positive Breast Cancer

Thomas Jefferson University

NCT04086875

ACTIVE NOT RECRUITING NA 256 participants

Culturally Based Brief Expressive Writing Intervention for the Improvement of Health in Chinese Immigrant Stage 0-III Breast Cancer Survivors, Writing to Heal Study

M.D. Anderson Cancer Center

NCT04754412

ACTIVE NOT RECRUITING Phase 2 249 participants

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

ECOG-ACRIN Cancer Research Group

NCT04001829

ACTIVE NOT RECRUITING NA 103 participants

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

Rutgers, The State University of New Jersey

NCT04871516

ACTIVE NOT RECRUITING NA 95 participants

Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy

M.D. Anderson Cancer Center

NCT05049746

ACTIVE NOT RECRUITING NA 62 participants

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

OHSU Knight Cancer Institute

NCT04993313

ACTIVE NOT RECRUITING NA 61 participants

Intensity Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Treating Patients With Lymph-Node Positive Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT03786354

ACTIVE NOT RECRUITING Phase 2 33 participants

STEMVAC in Patients With Early Stage Triple Negative Breast Cancer

University of Washington

NCT05455658

ACTIVE NOT RECRUITING NA 30 participants

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT05025059

ACTIVE NOT RECRUITING NA 4 participants

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Ohio State University Comprehensive Cancer Center

NCT04537312

COMPLETED NA 452 participants

Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer

M.D. Anderson Cancer Center

NCT00507923

COMPLETED Phase 2 130 participants

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

Ohio State University Comprehensive Cancer Center

NCT04862585

COMPLETED NA 50 participants

An Episodic Future Thinking Intervention to Promote Weight Loss in Breast Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT05012176

COMPLETED NA 27 participants

Weight Bearing Exercise in Preventing Frailty in Stage I-IIIA Breast Cancer Survivors

University of Arizona

NCT03708055

COMPLETED NA 23 participants

Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer

Wake Forest University Health Sciences

NCT03505671

COMPLETED Phase 1 20 participants

M7824 in Treating Patients With Stage II-III HER2 Positive Breast Cancer

M.D. Anderson Cancer Center

NCT03620201

COMPLETED Phase 1 15 participants

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

M.D. Anderson Cancer Center

NCT03774472

COMPLETED Phase 1 11 participants

Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT04205903

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 6
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anatomic Stage IIA Breast Cancer AJCC v8 Trial Landscape

34 indexed Anatomic Stage IIA Breast Cancer AJCC v8 studies · 9 recruiting (26%).

Phase mix: 1 late (III/IV) vs 12 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (9 trials), 9 others listed. 34 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anatomic Stage IIA Breast Cancer AJCC v8?

PlainTrial tracks 34 US clinical trials for Anatomic Stage IIA Breast Cancer AJCC v8, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anatomic Stage IIA Breast Cancer AJCC v8?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.