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NCT00081419 · ClinicalTrials.gov registry record
Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder
A clinical trial of Tourette Syndrome and Tic Disorders, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 42
- Enrollment target
- 1
- Study location
NCT00081419: Completed study of Tourette Syndrome and Tic Disorders, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00081419 is a study of Tourette Syndrome and Tic Disorders that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 42 participants, below the 85-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00081419, a study of Tourette Syndrome and Tic Disorders, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine how the brain controls movement in people with Tourette syndrome and chronic tic disorder to determine if the timing of movement is important in whether someone feels "in control" of their movements. Although movements in tic disorders are often characterized as "involuntary," some patients claim that these movements are made voluntarily, or they are unable to decide if they are voluntary or involuntary. Previous experiments have shown that when people are asked to look at a clock and report the time they first decide to make a movement they report times later than the first brain waves associated with movement appear. When they are asked to report the time they first initiate the movement, they report times before the muscles actually begin to move. This study may help determine how the sense of willing and initiating an action is altered in patients with Tourette syndrome and chronic tic disorder, and how people may feel more or less "in control" of their movements. Normal volunteers and patients with Tourette syndrome or chronic tic disorder between 18 and 65 years of age may be eligible for this study. Control subjects must not have any neurological or psychological disorders, and patients with Tourette syndrome of chronic tic disorder must not have any other neurological disorders. Patients with attention deficit hyperactivity disorder (ADHD) may not enroll in this study. All participants will have a medical history, physical examination, and a test to determine their level of attention. Patients will be interviewed about their symptoms and complete psychiatric rating scales. In addition, all participants will undergo the following procedures: Electric shock Participants look at a clock on a computer screen, the hands of which revolves quickly. While looking at the clock, each participant will be given small, non-painful electric shocks and asked, according to the clock, to say when they received the shocks. The shocks are repeated 4
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2004-04-08 |
| Est. Completion | 2009-01-12 |
What the finished NCT00081419 record still lists
NCT00081419 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 85-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (51% lower).
The record links to 2 conditions, with Tourette Syndrome appearing as the primary indexed condition, and to 0 interventions.
NCT00081419 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00081419 about?
NCT00081419 is a clinical study titled "Timing of Voluntary Movement in Patients With Tourette Syndrome and Chronic Tic Disorder". This study will examine how the brain controls movement in people with Tourette syndrome and chronic tic disorder to determine if the timing of movement is important in whether someone feels "in control" of their movements. Although movements in tic disorders are often characterized as "involuntary,...
What is the current status of trial NCT00081419?
This trial is currently completed. The enrollment target is 42 participants. The study started on 2004-04-08. Estimated completion is 2009-01-12.
What conditions does trial NCT00081419 study?
This clinical trial studies the following conditions: Tourette Syndrome, Tic Disorders.
Who is sponsoring clinical trial NCT00081419?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00081419 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tourette Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00081419's enrollment target sits among peer trials
42 20th of 33 higher than 14 of 33 other Tourette Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tourette Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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