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NCT04449003 · ClinicalTrials.gov registry record
Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome
A clinical trial of Tourette Syndrome and Tourette Syndrome in Adolescence, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- 66
- Enrollment target
- 1
- Study location
NCT04449003: Completed study of Tourette Syndrome and Tourette Syndrome in Adolescence, sponsored by Vanderbilt University Medical Center.
NCT04449003 is a study of Tourette Syndrome and Tourette Syndrome in Adolescence that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 66 participants, below the 85-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (22% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04449003, a study of Tourette Syndrome and Tourette Syndrome in Adolescence, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- 66 participants
- Enrollment target
- 1
- Study location
Study Summary
Investigators propose a cross-sectional, observational pilot study to examine the contribution of stress, family dynamics, and peer relationships to quality of life (QOL) in adolescents with Tourette syndrome (TS). Investigators will recruit two groups of participants: 1) adolescents aged 13-17 years of age with TS and 2) adolescents aged 13-17 without any neurologic or psychiatric diagnoses. Participants and one of their parents/caregivers will complete a series of questionnaires screening for and quantifying the extent of stress and mental health symptoms, including anxiety, depression, obsessive compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD). Participants will also complete instruments characterizing family interactions and peer relationships. Adolescents with TS will also undergo a semi-structured interview assessing the severity of their tics.
Primary Outcome
Self-report quality of life scale comprised of 42 items with 10-point Likert scale (raw total score 0-420) and 15 additional items with open-ended and demographic questions. Higher scores indicate better overall quality of life.
Conditions Studied
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 66 participants |
| Start Date | 2021-03-29 |
| Est. Completion | 2023-02-10 |
What the finished NCT04449003 record still lists
NCT04449003 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 85-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (22% lower).
The record links to 3 conditions, with Tourette Syndrome appearing as the primary indexed condition, and to 0 interventions.
NCT04449003 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT04449003 about?
NCT04449003 is a clinical study titled "Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome". Investigators propose a cross-sectional, observational pilot study to examine the contribution of stress, family dynamics, and peer relationships to quality of life (QOL) in adolescents with Tourette syndrome (TS). Investigators will recruit two groups of participants: 1) adolescents aged 13-17 year...
What is the current status of trial NCT04449003?
This trial is currently completed. The enrollment target is 66 participants. The study started on 2021-03-29. Estimated completion is 2023-02-10.
What conditions does trial NCT04449003 study?
This clinical trial studies the following conditions: Tourette Syndrome, Tourette Syndrome in Adolescence, Tourette Syndrome in Children.
Who is sponsoring clinical trial NCT04449003?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04449003 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tourette Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04449003's enrollment target sits among peer trials
66 13th of 33 higher than 21 of 33 other Tourette Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tourette Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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RECRUITING · NA
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Longitudinal Impact of Stressors in Adults With Tourette Syndrome
RECRUITING
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