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ClinicalTrials.gov 14 recruiting now later-stage tilt

Erectile Dysfunction: later-stage trial registry

14 of 34 indexed Erectile Dysfunction trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #451 of 28,707 conditions by registered trial count.

34 US clinical trials · 14 currently recruiting · #451 of 28,707 conditions by registered trial count

Erectile Dysfunction: 34 US clinical trials tracked, 14 recruiting.

Erectile Dysfunction is the subject of 34 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 3 of these trials.

Enrollment posture brief

Registry condition erectile-dysfunction

OPEN 14 | RECR 41% | LATE 10 | EARLY 4 | RANK #451 | SPON 3

Nearest open-share peer: Fragile X Syndrome (41% recruiting · 17 trials)

Healthy Adults44.1%Erectile Dysfunction (this)41%Anatomic Stage IIIB Breast C32.4%Anatomic Stage IIA Breast Ca26.5%Dry Eye Disease14.7%
Open-enrollment share among volume-matched conditions near Erectile Dysfunction

Erectile Dysfunction lists 14 open slots (41% of 34 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Erectile Dysfunction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Erectile Dysfunction recruits in line with its size-band peers.

    14 of 34 indexed trials (41.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Erectile Dysfunction trials is spread across many organizations.

    Mayo Clinic accounts for 3 of 34 trials (8.8%). 25 distinct sponsors appear on at least one study for this condition label.

  3. Typical Erectile Dysfunction enrolment sits around 74 participants.

    Median target enrolment is 74 among the 34 trials that report a genuine target (sentinel values excluded). 19 of those (55.9%) plan for fewer than 100 participants.

  4. Erectile Dysfunction research is mostly interventional.

    32 interventional and 2 observational studies make up this index (94.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 39Phase 41

Open and recent trials

34 total, page 1 of 1

RECRUITING Phase 3 2,250 participants

Actual Use Trial of Tadalafil 5 mg

Sanofi

NCT06805513

RECRUITING NA 224 participants

Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery

Memorial Sloan Kettering Cancer Center

NCT02706561

RECRUITING Phase 3 196 participants

SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)

Icahn School of Medicine at Mount Sinai

NCT06945315

RECRUITING NA 186 participants

Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain

The Cleveland Clinic

NCT05868668

RECRUITING NA 120 participants

EndoPAT Device for Endothelial Dysfunction in ED

University of California, Irvine

NCT06720597

RECRUITING NA 98 participants

Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED

OHH-MED Medical

NCT06167733

RECRUITING NA 60 participants

Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease

Mayo Clinic

NCT06065436

RECRUITING NA 48 participants

Penile Lengthening Pre-Penile Prosthesis Implantation

University of Pittsburgh

NCT07053826

RECRUITING NA 46 participants

The Impact of Dietary Pattern on Erectile Function

Montefiore Medical Center

NCT04349059

RECRUITING NA 30 participants

The Impact of a Plant-based Meat Meal Versus an Animal Meat Meal on Erectile Function in Healthy Men.

Montefiore Medical Center

NCT06273592

RECRUITING NA 15 participants

Prostate Stimulation for Sexual Dysfunction

Stanford University

NCT05468931

RECRUITING Phase 1 12 participants

The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects

Aspargo Labs

NCT06872866

RECRUITING NA 10 participants

Double-S: a Wearable Device for Erectile Dysfunction

Stanford University

NCT05451563

RECRUITING NA 9 participants

External Device for Erectile Dysfunction (3D-Erect)

Stanford University

NCT04624126

ACTIVE NOT RECRUITING Early Phase 1 800 participants

Collaborative Urological Prosthetics Investigation Directive Research Group

University of Chicago

NCT05100654

ACTIVE NOT RECRUITING NA 338 participants

Low Intensity Shockwave Therapy for Erectile Dysfunction

University of Virginia

NCT04434352

ACTIVE NOT RECRUITING Phase 3 200 participants

Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement

Rush University Medical Center

NCT06489431

ACTIVE NOT RECRUITING 126 participants

Penile Injection Anxiety

Memorial Sloan Kettering Cancer Center

NCT00582231

COMPLETED Phase 3 732 participants

A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction

Bayer

NCT00665496

COMPLETED Phase 3 618 participants

Treatment of Erectile Dysfunction I

Warner Chilcott

NCT01037244

COMPLETED Phase 3 601 participants

Treatment of Erectile Dysfunction II

Warner Chilcott

NCT01037218

COMPLETED Phase 3 290 participants

Study of Sildenafil Citrate During and After Radiotherapy/Hormone Therapy for Erectile Function Versus Radiotherapy/Hormone Therapy for Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT00142506

COMPLETED Phase 3 229 participants

Study to Investigate the Efficacy and Safety of Vardenafil Flexible Dose Versus Placebo in Males With Erectile Dysfunction

Bayer

NCT00657033

COMPLETED Phase 4 131 participants

A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy

Astellas Pharma

NCT00106392

COMPLETED Phase 3 74 participants

An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms

Chesapeake Urology Research Associates

NCT00893113

COMPLETED Phase 1 48 participants

Drug Interaction Study of Avanafil and Enalapril or Amlodipine

VIVUS

NCT01117038

COMPLETED NA 40 participants

Evaluation of the Coloplast Titan® IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)

Coloplast A/S

NCT00731666

COMPLETED NA 40 participants

Autologous Bone Marrow Concentrate in Treatment of Erectile Dysfunction.

Creative Medical Health

NCT03699943

COMPLETED 30 participants

The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction

Milton S. Hershey Medical Center

NCT00284960

COMPLETED NA 15 participants

Use of an External Erectile Device in Transgender Man Following Phalloplasty

Boston Children's Hospital

NCT03823014

COMPLETED NA 12 participants

Transpelvic Magnetic Stimulation to Improve Urogenital Function

VA Office of Research and Development

NCT04488068

COMPLETED NA 6 participants

Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)

University Hospitals Cleveland Medical Center

NCT00256399

COMPLETED NA 6 participants

Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction

Mayo Clinic

NCT04136288

COMPLETED Phase 1 4 participants

PRP for the Treatment of Erectile Dysfunction (ED)

Mayo Clinic

NCT04350125

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 3 9
Phase 4 1

Named interventions

Most-linked intervention names on Erectile Dysfunction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Levitra (Vardenafil, BAY38-9456) Drug
2 trials
Udenafil Drug
2 trials
Autologous Platelet Rich Plasma Biological
1 trials
Elator Device
1 trials
MoreNova Device
1 trials
Alfuzosin 10 mg Drug
1 trials
placebo tablets and questionaires Drug
1 trials

US sites by state

Facility locations filed on Erectile Dysfunction trials. A trial with sites in several states counts in each.

California 12 trials
New York 10 trials
Florida 8 trials
Arizona 5 trials
Ohio 4 trials
Maryland 4 trials
Illinois 4 trials
Connecticut 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Erectile Dysfunction page

34 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 14 Erectile Dysfunction trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Mayo Clinic sponsors the most Erectile Dysfunction trials on record, review their full trial history before evaluating a specific study. See Mayo Clinic's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Erectile Dysfunction condition card totals 34 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.