Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Erectile Dysfunction clinical trials
Every US clinical trial registered for Erectile Dysfunction — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
34 US clinical trials · 14 currently recruiting
The research picture
Erectile Dysfunction has 34 registered US clinical trials, 14 of them open to new participants right now — about 41% of the total.
- 14
- recruiting participants now
- 41%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Mayo Clinic
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Actual Use Trial of Tadalafil 5 mg
Sanofi
NCT06805513
Helping Men Adhere to Sexual Rehabilitation Following Prostate Cancer Surgery
Memorial Sloan Kettering Cancer Center
NCT02706561
SAFE Nerve Sparing Guided by Micro-ultrasound (MUS)
Icahn School of Medicine at Mount Sinai
NCT06945315
Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain
The Cleveland Clinic
NCT05868668
EndoPAT Device for Endothelial Dysfunction in ED
University of California, Irvine
NCT06720597
Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
OHH-MED Medical
NCT06167733
Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
Mayo Clinic
NCT06065436
Penile Lengthening Pre-Penile Prosthesis Implantation
University of Pittsburgh
NCT07053826
The Impact of Dietary Pattern on Erectile Function
Montefiore Medical Center
NCT04349059
The Impact of a Plant-based Meat Meal Versus an Animal Meat Meal on Erectile Function in Healthy Men.
Montefiore Medical Center
NCT06273592
Prostate Stimulation for Sexual Dysfunction
Stanford University
NCT05468931
The Objective of This Phase 1 Study is to Evaluate the Food Effect of 100 mg Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fed Versus 100 mg of Hezkue Turbo® (ASP-001.1, Sildenafil) Under Fasted Conditions in Healthy Adult Male Subjects
Aspargo Labs
NCT06872866
Double-S: a Wearable Device for Erectile Dysfunction
Stanford University
NCT05451563
External Device for Erectile Dysfunction (3D-Erect)
Stanford University
NCT04624126
Collaborative Urological Prosthetics Investigation Directive Research Group
University of Chicago
NCT05100654
Low Intensity Shockwave Therapy for Erectile Dysfunction
University of Virginia
NCT04434352
Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
Rush University Medical Center
NCT06489431
Penile Injection Anxiety
Memorial Sloan Kettering Cancer Center
NCT00582231
A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction
Bayer
NCT00665496
Treatment of Erectile Dysfunction I
Warner Chilcott
NCT01037244
Treatment of Erectile Dysfunction II
Warner Chilcott
NCT01037218
Study of Sildenafil Citrate During and After Radiotherapy/Hormone Therapy for Erectile Function Versus Radiotherapy/Hormone Therapy for Prostate Cancer
Memorial Sloan Kettering Cancer Center
NCT00142506
Study to Investigate the Efficacy and Safety of Vardenafil Flexible Dose Versus Placebo in Males With Erectile Dysfunction
Bayer
NCT00657033
A Safety and Efficacy Study of Prograf in the Prevention of Erectile Dysfunction After Radical Prostatectomy
Astellas Pharma
NCT00106392
An Efficacy Study to Evaluate Alfuzosin to Treat Men With Erectile Dysfunction and Mild Lower Urinary Tract Symptoms
Chesapeake Urology Research Associates
NCT00893113
Drug Interaction Study of Avanafil and Enalapril or Amlodipine
VIVUS
NCT01117038
Evaluation of the Coloplast Titan® IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)
Coloplast A/S
NCT00731666
Autologous Bone Marrow Concentrate in Treatment of Erectile Dysfunction.
Creative Medical Health
NCT03699943
The Incidence and Treatment of Insulin Resistance Among Men With Erectile Dysfunction
Milton S. Hershey Medical Center
NCT00284960
Use of an External Erectile Device in Transgender Man Following Phalloplasty
Boston Children's Hospital
NCT03823014
Transpelvic Magnetic Stimulation to Improve Urogenital Function
VA Office of Research and Development
NCT04488068
Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)
University Hospitals Cleveland Medical Center
NCT00256399
Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction
Mayo Clinic
NCT04136288
PRP for the Treatment of Erectile Dysfunction (ED)
Mayo Clinic
NCT04350125
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 3 | 9 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Erectile Dysfunction Trial Landscape
ClinicalTrials.gov lists 34 US studies indexed under Erectile Dysfunction, and 14 of those are currently open to recruitment — roughly 41% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Erectile Dysfunction shows 10 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Erectile Dysfunction is led by Mayo Clinic with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 34 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Erectile Dysfunction?
PlainTrial tracks 34 US clinical trials for Erectile Dysfunction, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Erectile Dysfunction?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.