Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05016765 · ClinicalTrials.gov registry record · NA

Open-label MNS for Tourette Syndrome

A NA study of Tourette Syndrome and Tic Disorder, Chronic Motor or Vocal, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
31
Enrollment target
1
Study location

NCT05016765: Completed NA study of Tourette Syndrome and Tic Disorder, Chronic Motor or Vocal, sponsored by Washington University School of Medicine.

NCT05016765 is a NA study of Tourette Syndrome and Tic Disorder, Chronic Motor or Vocal that has completed, run by Washington University School of Medicine. The registered enrollment target is 31 participants, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05016765, a NA study of Tourette Syndrome and Tic Disorder, Chronic Motor or Vocal, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
31 participants
Enrollment target
1
Study location

Study Summary

A recent report (Morera Maiquez et al 2020) described reduced tic severity in people with Tourette syndrome during 1-minute epochs of median nerve stimulation (MNS) at 10 Hz. Among the various questions still to be answered is the question of whether a device to administer MNS is practical for use in a chronic, real-world setting. This study will recruit participants who complete the clinic-based, blinded, randomized controlled trial, https://clinicaltrials.gov/ct2/show/NCT04731714, to determine the real-world usage and apparent utility of median nerve stimulation in people with chronic tics.

Primary Outcome

Number of minutes per day the device was used, only counting days in which the device was turned on, over the four-week period after the initial visit

Interventions

  • DEVICE Active, self-directed electrical stimulation of the median nerve

Study Locations (1)

Missouri

  • Washington University School of Medicine, Movement Disorders Center - St Louis

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2021-11-18
Est. Completion 2022-04-27
Phase NA

What the finished NCT05016765 record still lists

NCT05016765 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (64% lower).

The record links to 2 conditions, with Tourette Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Active, self-directed electrical stimulation of the median nerve is the first listed.

NCT05016765 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT05016765 about?

NCT05016765 is a clinical study titled "Open-label MNS for Tourette Syndrome". A recent report (Morera Maiquez et al 2020) described reduced tic severity in people with Tourette syndrome during 1-minute epochs of median nerve stimulation (MNS) at 10 Hz. Among the various questions still to be answered is the question of whether a device to administer MNS is practical for use i...

What is the current status of trial NCT05016765?

This trial is currently completed. It is a NA study. The enrollment target is 31 participants. The study started on 2021-11-18. Estimated completion is 2022-04-27.

What conditions does trial NCT05016765 study?

This clinical trial studies the following conditions: Tourette Syndrome, Tic Disorder, Chronic Motor or Vocal.

What interventions are being tested in trial NCT05016765?

The interventions under investigation include: Active, self-directed electrical stimulation of the median nerve (DEVICE).

Who is sponsoring clinical trial NCT05016765?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05016765 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Tourette Syndrome

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05016765's enrollment target sits among peer trials

31 23rd of 33 higher than 11 of 33 other Tourette Syndrome trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Tourette Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02932618 · 31 participants · Phase 3

    A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)

  • NCT03482297 · 31 participants · Phase 1

    Automated Abdominal Binder for Orthostatic Hypotension

  • NCT04016389 · 31 participants · NA

    FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery

  • NCT04211675 · 31 participants · Phase 1

    NK Cells Infusions With Irinotecan, Temozolomide, and Dinutuximab

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05016765, the US trial registry maintained by the National Library of Medicine. NCT05016765 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.