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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Addiction: early-phase trial registry

5 of 17 indexed Addiction trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 5 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Addiction: 17 US clinical trials tracked, 5 recruiting.

Addiction is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Yale University, running 3 of these trials.

Enrollment posture brief

Registry condition addiction

OPEN 5 | RECR 29% | LATE 0 | EARLY 4 | RANK #1004 | SPON 3

Nearest open-share peer: Arthritis, Psoriatic (29% recruiting · 17 trials)

Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Addiction (this)29%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Addiction

Addiction lists 5 open slots (29% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Addiction on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Addiction is recruiting below its size-band peers.

    5 of 17 indexed trials (29.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Addiction research.

    Yale University accounts for 3 of 17 trials (17.6%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Addiction enrolment sits around 100 participants.

    Median target enrolment is 100 among the 17 trials that report a genuine target (sentinel values excluded). 8 of those (47.1%) plan for fewer than 100 participants.

  4. Addiction research is mostly interventional.

    15 interventional and 2 observational studies make up this index (88.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 22

Open and recent trials

17 total, page 1 of 1

RECRUITING NA 400 participants

Behavioral and Functional Task Development, Implementation, and Testing

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02108054

RECRUITING NA 360 participants

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

Johns Hopkins University

NCT06103370

RECRUITING 200 participants

Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics

Yale University

NCT06624137

RECRUITING Phase 2 52 participants

Semaglutide Therapy for Alcohol Reduction (STAR)

National Institute on Drug Abuse (NIDA)

NCT06015893

RECRUITING NA 40 participants

Tdcs And cogNitive traininG cOmbined for AUD (TANGO)

University of Minnesota

NCT05062369

ACTIVE NOT RECRUITING NA 405 participants

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care

Johns Hopkins University

NCT04601064

ACTIVE NOT RECRUITING NA 100 participants

Group Activities to Support Addiction Recovery

University of Nebraska

NCT07071883

ACTIVE NOT RECRUITING NA 10 participants

Breathwork-assisted Treatment for Cannabis Use Disorder

Elias Dakwar

NCT05219825

COMPLETED 6,967 participants

Screening Protocol for the Evaluation of Potential Research Subjects

National Institute on Drug Abuse (NIDA)

NCT01036971

COMPLETED NA 2,118 participants

Providing Mental Health Precision Treatment

University of Michigan

NCT04342494

COMPLETED NA 161 participants

An Addiction-Based Mobile Health Weight Loss Intervention With Coaching

Children's Hospital Los Angeles

NCT03500835

COMPLETED Phase 2 118 participants

Perioperative Pregabalin in Ureteroscopy

University of Missouri-Columbia

NCT04122196

COMPLETED NA 81 participants

Journaling and Addiction Recovery: Piloting "Positive Recovery Journaling"

University of Minnesota

NCT04458181

COMPLETED NA 35 participants

Cognitive Effects of Atomoxetine in Humans: Genetic Moderators

Yale University

NCT01498549

COMPLETED NA 15 participants

Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App

Milton S. Hershey Medical Center

NCT03826966

COMPLETED Early Phase 1 15 participants

Reducing the Abuse Liability of Prescription Opioids

The University of Texas Health Science Center at San Antonio

NCT04587115

COMPLETED Early Phase 1 7 participants

Safety and Tolerability of Cannabidiol Among Persons With Opioid Use Disorder Receiving Methadone or Buprenorphine

Yale University

NCT05076370

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2

Named interventions

Most-linked intervention names on Addiction records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Clinic: Modified KidsNFitness Behavioral
1 trials
Coaching Behavioral
1 trials
Positive Peer Journaling (PPJ) Behavioral
1 trials
reSET Device
1 trials
Pregabalin 300mg Drug
1 trials
CBD Day 3 Drug
1 trials
CBD Day 2 Drug
1 trials
CBD Day 1 Drug
1 trials

US sites by state

Facility locations filed on Addiction trials. A trial with sites in several states counts in each.

Maryland 5 trials
Connecticut 3 trials
Minnesota 2 trials
Texas 1 trials
Pennsylvania 1 trials
New York 1 trials
Nebraska 1 trials
Missouri 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Addiction page

17 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Addiction condition card totals 17 registered trials; most-linked intervention Clinic: Modified KidsNFitness; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.