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NCT05705999 · ClinicalTrials.gov registry record · NA

Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study

A NA study of Tourette Syndrome, sponsored by West Virginia University.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT05705999 is a NA study of Tourette Syndrome that is actively recruiting participants, run by West Virginia University. The registered enrollment target is 20 participants, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05705999, a NA study of Tourette Syndrome, is actively recruiting participants, sponsored by West Virginia University.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

This pilot study will investigate the clinical and neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) followed by comprehensive behavioral intervention for tics (CBIT) in adult patients with Tourette's Syndrome (TS). Two groups of moderate disease severity will be randomized to receive active or sham rTMS targeted to the supplementary motor area (SMA) followed by eight CBIT sessions. The change in tic frequency and severity (primary outcome) and neurophysiological changes (secondary outcome) will be compared between the two groups. The central hypothesis is that low frequency rTMS will augment the effects of CBIT through favorable priming of the SMA network.

Conditions Studied

Interventions

  • DEVICE transcranial magnetic stimulation

Study Locations (1)

West Virginia

  • WVU RNI - Morgantown

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-03-12
Est. Completion 2026-12-30
Phase NA

Sponsor

West Virginia University

122 total trials

What the Registry Record Tells You About NCT05705999

The ClinicalTrials.gov registry entry for NCT05705999 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (77% lower). The listed sponsor is West Virginia University, which has 122 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Tourette Syndrome appearing as the primary indexed condition, and to 1 intervention - of which transcranial magnetic stimulation is the first listed.

NCT05705999 reports 1 study location spanning 1 distinct geographic area - top geographies include West Virginia.

Frequently Asked Questions

What is clinical trial NCT05705999 about?

NCT05705999 is a clinical study titled "Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study". This pilot study will investigate the clinical and neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) followed by comprehensive behavioral intervention for tics (CBIT) in adult patients with Tourette's Syndrome (TS). Two groups of moderate disease severity will be rand...

What is the current status of trial NCT05705999?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-03-12. Estimated completion is 2026-12-30.

What conditions does trial NCT05705999 study?

This clinical trial studies the following conditions: Tourette Syndrome.

What interventions are being tested in trial NCT05705999?

The interventions under investigation include: transcranial magnetic stimulation (DEVICE).

Who is sponsoring clinical trial NCT05705999?

This trial is sponsored by West Virginia University, which has 122 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05705999 being conducted?

This trial has 1 study location across West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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