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NCT01258790 · ClinicalTrials.gov registry record · NA

Repetitive Transcranial Magnetic Stimulation to Reduce Tics

A NA study of Tourette Syndrome, sponsored by Children's Hospital Medical Center, Cincinnati.

Completed
Registry status
NA
Development phase
12
Enrollment target
1
Study location

NCT01258790: Completed NA study of Tourette Syndrome, sponsored by Children's Hospital Medical Center, Cincinnati.

NCT01258790 is a NA study of Tourette Syndrome that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 12 participants, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01258790, a NA study of Tourette Syndrome, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Specific Aim1: Using a paradigm of Transcranial Magnetic Stimulation called Continuous Theta Burst Stimulation (cTBS) to reduce tics in Tourette Syndrome subjects Hypothesis1: cTBS, compared to sham stimulation, will reduce tic severity by at least 25% as measured by the Yale Global Tic Severity Scale Specific Aim2: Using cTBS to further understand neural correlates of tic generation Hypothesis2: Functional MRI BOLD signal activation pattern will change after cTBS and this change will correlate with clinical improvement in tic severity

Primary Outcome

The tic severity score based on Yale Global Tic Severity Scale ranges from 0 - 50. A person who has no tics would have a score of 0. High score means a person has severe tics.

Conditions Studied

Interventions

  • DEVICE Sham Repetitive Transcranial Magnetic Stimulation
  • DEVICE Active Repetitive Transcranial Magnetic Stimulation

Study Locations (1)

Ohio

  • Cincinnati Children's Medical Center - Cincinnati

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2010-11
Est. Completion 2013-03
Phase NA

What the finished NCT01258790 record still lists

NCT01258790 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 86-participant average among 33 other Tourette Syndrome trials with a reported enrollment target (86% lower).

The record links to 1 condition, with Tourette Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Sham Repetitive Transcranial Magnetic Stimulation is the first listed.

NCT01258790 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT01258790 about?

NCT01258790 is a clinical study titled "Repetitive Transcranial Magnetic Stimulation to Reduce Tics". Specific Aim1: Using a paradigm of Transcranial Magnetic Stimulation called Continuous Theta Burst Stimulation (cTBS) to reduce tics in Tourette Syndrome subjects Hypothesis1: cTBS, compared to sham stimulation, will reduce tic severity by at least 25% as measured by the Yale Global Tic Severity Sc...

What is the current status of trial NCT01258790?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2010-11. Estimated completion is 2013-03.

What conditions does trial NCT01258790 study?

This clinical trial studies the following conditions: Tourette Syndrome.

What interventions are being tested in trial NCT01258790?

The interventions under investigation include: Sham Repetitive Transcranial Magnetic Stimulation (DEVICE), Active Repetitive Transcranial Magnetic Stimulation (DEVICE).

Who is sponsoring clinical trial NCT01258790?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01258790 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Tourette Syndrome

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01258790's enrollment target sits among peer trials

12 30th of 33 higher than 3 of 33 other Tourette Syndrome trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Tourette Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01258790, the US trial registry maintained by the National Library of Medicine. NCT01258790 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.